Wu Tsai Neurosciences Institute
Showing 301-320 of 672 Results
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Peter S. Kim
Virginia and D. K. Ludwig Professor of Biochemistry
Current Research and Scholarly InterestsOur research focuses on developing new strategies for vaccine creation. We also aim to generate vaccines targeting infectious agents that have eluded efforts to date. We integrate experimental approaches with protein language models to guide artificial evolution and enable efficient antibody and protein engineering. Our interdisciplinary approach aims to address critical global health challenges.
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Seung K. Kim M.D., Ph.D.
KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
Current Research and Scholarly InterestsPancreatic islets are essential for human health. We study the development and function of islet cells using modern methods in several model systems, including mice, pigs, human pancreas, primates, embryonic stem cells, and fruit flies. We have discovered critical factors required for islet development and mature islet cell function. These approaches have informed efforts to generate replacement islets, and provide immune protection of transplanted islets for diabetes.
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Benyam Z. Kinde, MD, PhD
Assistant Professor of Ophthalmology
BioDr. Kinde is a board-certified, fellowship-trained ophthalmologist and ophthalmic plastic and reconstructive surgeon at Stanford Health Care Byers Eye Institute. He is also an assistant professor in the Department of Ophthalmology at Stanford University School of Medicine. Dr. Kinde completed the American Society of Ophthalmic and Plastic Reconstructive Surgery (ASOPRS) fellowship in ophthalmic plastic surgery through the Bascom Palmer Eye Institute at the University of Miami.
Dr. Kinde diagnoses and treats a wide range of conditions related to the eyelid and other eye structures, including facial nerve palsy, skin cancer, and thyroid eye disease. He also provides care for patients who wish to enhance their appearance through surgical and nonsurgical interventions. Dr. Kinde offers many types of treatments, including cosmetic surgery, eyelid surgery (including upper and lower eyelid blepharoplasty and ptosis surgery), reconstructive surgery, tear duct (lacrimal) surgery, and orbital surgery.
Dr. Kinde is a physician-scientist whose research interests focus on developing new tools to promote survival of retinal ganglion cells after optic nerve injury. He has investigated how modulating the DNA damage response in mouse models of traumatic optic neuropathy (symptoms of nerve damage) may promote and improve optic nerve function after injury. His previous work focused on increasing the resilience of neurons (messaging nerve cells) in mouse models of glaucoma and in humans with glaucoma. He completed his MD and PhD in neuroscience at Harvard Medical School, where his thesis work revealed a new understanding of Rett syndrome, a rare genetic disorder that affects body movement.
Dr. Kinde has published in many peer-reviewed journals, including Nature, Science, Cell, Ophthalmology, and Facial Plastic Surgery & Aesthetic Medicine. He has presented to his peers at international and national meetings, including the Association for Research in Vision and Ophthalmology, American Society of Ophthalmic Plastic and Reconstructive Surgery, and Inter-American Course in Clinical Ophthalmology. -
David Kingsley
Rudy J. and Daphne Donohue Munzer Professor in the School of Medicine
Current Research and Scholarly InterestsWe use mice, stickleback fish, and humans to study the molecular basis of evolution and common diseases. By combining genetics and genomics, we have identified key DNA changes that control bone formation, limb patterning, hair color, brain evolution, and susceptibility to arthritis, schizophrenia, and bipolar disorder. We find that the same genetic mechanisms are often used repeatedly in nature, providing new insights into the origin of key traits in many different species, including ourselves.
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Amanda Kirane, MD, PhD, FACS, FSSO
Associate Professor of Surgery (General Surgery)
BioDr. Kirane is a fellowship-trained, board-certified specialist in complex general surgical oncology. She is an Associate Professor in the Department of Surgery, Section of Surgical Oncology, at Stanford University School of Medicine. Dr. Kirane serves as Director of Cutaneous Surgical Oncology and Surgical Lead of Solid Tumor Cell Therapy at the Stanford Cancer Institute and her clinical practice focuses on the diagnosis and treatment of melanoma and other skin cancers. She partners closely with patients and families to provide the most effective treatment approach possible. For each patient, she tailors an evidence-based, personalized care plan that is innovative, comprehensive, and compassionate.
Dr. Kirane is Principal Investigator of multiple studies in melanoma and mechanisms of resistance to immunotherapy, with focus on myeloid biology. Her current interests include immune response and novel therapies in melanoma, predictive modeling of patient responses using organoid technology, and translational biomarker development. She has led research into immune therapy for earlier stage melanoma using regionally directed therapy to augment immune response in melanoma and trials in surgical care in melanoma.
The National Institutes of Health, American Society of Clinical Oncology, the Melanoma Research Alliance, and others have funded her research. She has co-authored articles on her discoveries in the Journal of Clinical Investigation, Nature Communications, Nature Genetics, Cancer Research, Journal of Surgical Oncology, Annals of Surgery, Annals of Surgical Oncology, and elsewhere. Topics include intratumoral therapy, biomarker development, macrophage biology in melanoma and immunotheraputic resistance, and patient-derived organoid modeling. Dr. Kirane has presented updates on the management of melanoma and other cancers to her peers at meetings of the American College of Surgeons, Society of Surgical Oncology, and Society for Immunotherapy in Cancer.
Dr. Kirane has earned awards for her achievements in clinical care, research, and scholarship. The Society for Immunotherapy of Cancer, Society of Surgical Oncology, Memorial Sloan Kettering Cancer Center, and other prestigious organizations have honored her work. She is a fellow of the American College of Surgeons (FACS) and Society of Surgical Oncology (FSSO). She is a member of the Society for Immunotherapy of Cancer, American Association of Cancer Research, Society for Melanoma Research, Connective Tissue Oncology Society, Association of Academic Surgeons, and Association of Women Surgeons.
She volunteers her time and expertise on behalf of the Melanoma Research Foundation, members of her community in need, STEM programs for girls, and other initiatives. She also is fellowship trained in Physician Wellness and Wellbeing and teaches somatic technique, mindfulness-based stress reduction, meditation, and breathwork. -
Juliet Klasing Knowles
Assistant Professor of Neurology and Neurological Sciences (Pediatric Neurology) and of Pediatrics
Current Research and Scholarly InterestsThe Knowles lab studies how white matter structure changes in different forms of epilepsy, and how aberrant white matter structure, in turn, shapes neuronal network function. In mouse models, we use a variety of innovative tools including neurophysiology, quantitative EEG, behavior, histological measures of white matter structure and MR imaging. We also conduct clinical research to study white matter abnormalities in children with epilepsy.
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Eric I. Knudsen
Edward C. and Amy H. Sewall Professor in the School of Medicine, Emeritus
Current Research and Scholarly InterestsCellular mechanisms of spatial attention and learning, studied in the central nervous system in birds, using behavioral, systems, cellular and molecular techniques.
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Brian Knutson
Professor of Psychology
Current Research and Scholarly InterestsMy lab and I seek to elucidate the neural basis of emotion (affective neuroscience), and explore implications for decision-making (neuroeconomics) and psychopathology (neurophenomics).
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Brian Kobilka
Hélène Irwin Fagan Chair of Cardiology
Current Research and Scholarly InterestsStructure, function and physiology of adrenergic receptors.
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Mykel Kochenderfer
Associate Professor of Aeronautics and Astronautics, Senior Fellow at the Stanford Institute for Human-Centered AI and Associate Professor, by courtesy, of Computer Science
BioMykel Kochenderfer is Associate Professor of Aeronautics and Astronautics at Stanford University. Prior to joining the faculty, he was at MIT Lincoln Laboratory where he worked on airspace modeling and aircraft collision avoidance, with his early work leading to the establishment of the ACAS X program. He received a Ph.D. from the University of Edinburgh and B.S. and M.S. degrees in computer science from Stanford University. Prof. Kochenderfer is the director of the Stanford Intelligent Systems Laboratory (SISL), conducting research on advanced algorithms and analytical methods for the design of robust decision making systems. Of particular interest are systems for air traffic control, unmanned aircraft, and other aerospace applications where decisions must be made in uncertain, dynamic environments while maintaining safety and efficiency. Research at SISL focuses on efficient computational methods for deriving optimal decision strategies from high-dimensional, probabilistic problem representations. He is an author of "Decision Making under Uncertainty: Theory and Application" (2015), "Algorithms for Optimization" (2019), and "Algorithms for Decision Making" (2022), all from MIT Press. He is a third generation pilot.
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Eric Kool
George A. and Hilda M. Daubert Professor of Chemistry
Current Research and Scholarly Interests• Design of cell-permeable reagents for profiling, modifying, and controlling RNAs
• Developing fluorescent probes of DNA repair pathways, with applications in cancer, aging, and neurodegenerative disease
• Discovery and development of small-molecule modulators of DNA repair enzymes, with focus on cancer and inflammation -
Ron Kopito
Professor of Biology
Current Research and Scholarly InterestsOur laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.
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Lorrin Koran
Professor (Clinical) of Psychiatry and Behavioral Sciences, Emeritus
Current Research and Scholarly Interestsobsessive-compulsive disorder, depressive disorders, psychopharmacology, cost-effectiveness studies, trichotillomania, compulsive buying, pathological gambling,kleptomania.
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Roger Kornberg
Mrs. George A. Winzer Professor of Medicine
Current Research and Scholarly InterestsWe study the regulation of transcription, the first step in gene expression. The main lines of our work are 1) reconstitution of the process with more than 50 pure proteins and mechanistic analysis, 2) structure determination of the 50 protein complex at atomic resolution, and 3) studies of chromatin remodelling, required for transcription of the DNA template in living cells
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Andrea Lora Kossler, MD, FACS
Associate Professor of Ophthalmology and, by courtesy, of Otolaryngology - Head & Neck Surgery
Current Research and Scholarly InterestsThyroid Eye Disease
Adenoid Cystic Carcinoma of the Lacrimal Gland
Lacrimal Gland Stimulation for the Treatment of Dry Eyes
Neurostimulation
Orbital Tumors
Floppy Eyelid Syndrome and Obstructive Sleep Apnea -
Gregory Kovacs
Professor of Electrical Engineering, Emeritus
Current Research and Scholarly InterestsHis present research areas include instruments for biomedical and biological applications including space flight, solid-state sensors and actuators, cell-based sensors for toxin detection and pharmaceutical screening, microfluidics, electronic interfaces to tissue, and biotechnology, all with emphasis on solving practical problems.
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Sanmi Koyejo
Associate Professor of Computer Science
BioSanmi Koyejo is an Assistant Professor in the Department of Computer Science at Stanford University and an adjunct Associate Professor at the University of Illinois at Urbana-Champaign. He leads the Stanford Trustworthy AI Research (STAIR) lab, which develops measurement-theoretic foundations for trustworthy AI systems, spanning AI evaluation science, algorithmic accountability, and privacy-preserving machine learning, with applications to healthcare and scientific discovery. His research on AI capabilities evaluation has challenged conventional understanding in the field, including work on measurement frameworks cited in the 2024 Economic Report of the President.
Koyejo has received the Presidential Early Career Award for Scientists and Engineers (PECASE), Skip Ellis Early Career Award, Alfred P. Sloan Research Fellowship, NSF CAREER Award, and multiple outstanding paper awards at flagship venues, including NeurIPS and ACL. He has delivered keynote presentations at major conferences, including ECCV and FAccT. He serves in key leadership roles, including Board President of Black in AI, Board of Directors of the Neural Information Processing Systems Foundation, and other leadership positions in professional organizations advancing AI research and broadening participation in the field. -
Elizabeth Bailey Kozleski
Affiliate, SAL Learning Differences
BioI engage in systems change and research on equity and justice issues in inclusive education in schools, school systems as well as state and national education organizations and agencies. My research interests include the analysis of systems change in education, how teachers learn in practice in complex, diverse school settings, including how educational practices improve student learning. Awards include the 2023 Luminary Award from the Division of Culturally and Linguistically Diverse Exceptional Children, Council of Exceptional Children; the 2018 Budig Award for Teaching Excellence in Special Education at the University of Kansas; the 2017 Boeing-Allan Visiting Endowed Chair at Seattle University; the University of Kansas 2016 Woman of Distinction award; the 2013 Scholar of the Century award from the University of Northern Colorado; the 2011 TED-Merrill award for leadership in special education teacher education in 2011; and the UNESCO Chair in Inclusive International Research. I co-lead the World Education Research Association International Research Network on Student Voice for Promoting Equity and Inclusion in Schools along with Professor Kyriaki Messiou of the University of South Hampton, UK.
A number of my articles focus on the design and development of teacher education programs that involve extensive clinical practice in general education settings. I have led the development of such programs in three universities, and continue to do research and development work in teacher education. I have also offered technical assistance as well as conducted research on the impact of technical assistance on individuals, as well as local, state, and national systems in the U.S. and abroad.
I have received funding for more than $35 million in federal, state, and local grants. I serve on the Board of Editors for the book series Inclusive Education and Partnerships, an international book series produced by Deep University. Recent books include Ability, Equity, and Culture (with co-author Kathleen King Thorius) published by Teachers College Press in ‘14 and Equity on Five Continents (with Alfredo Artiles and Federico Waitoller) published in ‘11 by Harvard Education Press. -
Mark Krasnow
Paul and Mildred Berg Professor
Current Research and Scholarly Interests- Lung development and stem cells
- Neural circuits of breathing and speaking
- Lung diseases including lung cancer
- New genetic model organism for biology, behavior, health and conservation -
Siddharth Krishnan
Assistant Professor of Electrical Engineering, and by courtesy, of Bioengineering and of Materials Science and Engineering
Current Research and Scholarly InterestsThe Krishnan Lab develops bioelectronic devices, tools and systems for closed loop disease management. Our work is divided into the following broad areas:
1. Biohybrid electronics for therapy and sensing: we combine living cells as functional parts of implantable devices, leveraging their ability to produce complex biologic therapeutics in a constitutive or triggerable manner, and their ability to sense their complex dynamic environment. These efforts are focused on developed functional cures for diseases like Type I Diabetes and other conditions requiring the regular infusion of proteins, peptides or antibody drugs.
2. Digital drug release systems for particulate forms of biologic drugs: Many complex protein and peptide drugs are not stable in solution, thereby frustrating the ability to delivery them through pumps and autoinjectors. This need is particularly acute for drugs that need to be administered as emergency rescue therapies, such as glucagon in the context of type 1 Diabetes. We develop implantable, miniaturized microelectromechanical devices that can store particulate (powders, pills) forms of these drugs and release them in a close loop manner based on wireless inputs from sensors.
3. Wearable sensors: Wearables to detect biophysical (temperature, flow, cardiac activity) and biochemical markers of health are gaining importance for closed-loop disease management and personalized medicine. We design hardware for on-chip molecular profiling based on sampling biofluids in noninvasive or minimally invasive formats.
4. New wireless power architectures for implantable bioelectronics: We develop high-power, high-efficiency strongly coupled power harvesting system to power battery-free implant systems.
