Wu Tsai Neurosciences Institute


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  • Billy W Loo Jr, MD PhD FASTRO FACR

    Billy W Loo Jr, MD PhD FASTRO FACR

    Professor of Radiation Oncology (Radiation Therapy)

    Current Research and Scholarly InterestsMy clinical specialty is precision targeted radiotherapy of thoracic cancers.

    My research is on developing next-generation ultra-rapid radiotherapy technology (PHASER) and studying the radiobiological effects of FLASH treatment.

    My clinical research is on advanced 4-D image-guided radiotherapy and stereotactic ablative radiotherapy (SABR), and functional and metabolic imaging and imaging biomarkers.

  • Jaime Lopez, MD

    Jaime Lopez, MD

    Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsMy clinical interests are in the areas of Intraoperative Neurophysiologic Monitoring (IOM), clinical neurophysiology, electromyopgraphy and in the use of botulinum toxins in the treatment of neurologic disorders. Our IOM group’s research is in the development of new and innovative techniques for monitoring the nervous system during surgical and endovascular procedures and how these alter surgical management and patient outcomes. I am also active in formulating national IOM practice guidelines.

  • Irene L. Llorente

    Irene L. Llorente

    Assistant Professor of Neurosurgery

    BioOriginally from Spain, Irene L. Llorente joined the Neurosurgery Department at Stanford University in 2022. Following her undergraduate degree in Molecular Biology at the University of Leon in Spain, Dr. Llorente completed an MS in Molecular Biology and Biomedicine and a Ph.D. in Neuroscience between the Universities of Leon (Spain) and Florence (Italy). She conducted a postdoctoral fellowship in the Neurology Department at the David Geffen School of Medicine at UCLA where she also started her independent career as a Research Assistant Professor. Her research interests are largely directed toward understanding the biology of white matter repair in central nervous system disorders. She is particularly interested in leveraging the current technologies emerging in the stem cell field to develop more efficient and effective stem cell-based therapies for stroke, spinal cord injury, Traumatic brain injury, and vascular dementia patients.

  • Christopher Lowe

    Christopher Lowe

    John B. and Jean De Nault Professor of Marine Science at the Hopkins Marine Station

    Current Research and Scholarly InterestsEvolution and development, specifically the evolution of the deuterostomes

  • Bingwei Lu

    Bingwei Lu

    Professor of Pathology

    Current Research and Scholarly InterestsWe are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer’s and Parkinson’s diseases. We are using both Drosophila and mammalian models to address these fundamental questions.

  • Lu,Guolan

    Lu,Guolan

    Assistant Professor of Urology

    Current Research and Scholarly InterestsThe Lu Lab develops and integrates AI, spatial multi-omics, and advanced imaging to understand and model how cells, tissues, and therapeutic agents interact in their native spatial context, and how these interactions drive disease progression and treatment response.

  • Emma Lundberg

    Emma Lundberg

    Associate Professor of Bioengineering and of Pathology

    BioDr. Emma Lundberg is an Associate Professor of Bioengineering and Pathology at Stanford University and serves at the Director of the Cell Atlas of the Human Protein Atlas initiative in Sweden, where she is also Professor at KTH Royal Institute of Technology. At the intersection of bioimaging, proteomics, and artificial intelligence, her research aims to define the spatiotemporal organization of the human proteome at both cellular and subcellular level. Dr. Lundberg aims to develop integrated models of human cells to elucidate how variations in protein localization patterns influence cellular function, ultimately enabling the simulation of cell behavior and a systems-level understanding of how biological information is spatially encoded. The Lundberg Lab is responsible for creating the Subcellular Atlas of the Human Protein Atlas database (https://www.proteinatlas.org/). Dr. Lundberg is dedicated to building virtual cell models to simulate cell behavior, and is passionate about engaging the public in her work through citizen science games and computational challenges.

    Dr. Lundberg holds a Master’s degree in Bioengineering and a PhD in Biotechnology from KTH Royal Institute of Technology in Sweden. She has served as Secretary General of the Human Proteome Organization, and is actively involved in advisory roles for numerous open-access databases and cell mapping efforts such as the CZI AI Virtual Cell, Human Cell Atlas consortium, UniProt db, Reactome db, Human Proteome Project and various pharma and biotech companies. As a token of her leadership skills and advocate for open science, she was twice recognized as top 10 under 40 for future leaders in biopharma and omics.

  • Liqun Luo

    Liqun Luo

    Ann and Bill Swindells Professor and Professor, by courtesy, of Neurobiology

    Current Research and Scholarly InterestsWe study how neurons are organized into specialized circuits to perform specific functions and how these circuits are assembled during development. We have developed molecular-genetic and viral tools, and are combining them with transcriptomic, proteomic, physiological, and behavioral approaches to study these problems. Topics include: 1) assembly of the fly olfactory circuit; 2) assembly of neural circuits in the mouse brain; 3) organization and function of neural circuits; 4) Tool development.

  • M Bruce MacIver

    M Bruce MacIver

    Professor (Research) of Anesthesiology, Perioperative and Pain Medicine, Emeritus

    Current Research and Scholarly InterestsWe study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.

  • Sean Mackey, M.D., Ph.D.

    Sean Mackey, M.D., Ph.D.

    Redlich Professor, Professor of Anesthesiology, Perioperative, and Pain Medicine (Adult Pain) and, by courtesy, of Neurology and Neurological Sciences
    On Leave from 01/25/2026 To 03/06/2026

    Current Research and Scholarly InterestsMultiple NIH funded projects to characterize CNS mechanisms of human pain. Comparative effectiveness of cognitive behavioral therapy and chronic pain self-management within the context of opioid reduction (PCORI funded). Single session pain catastrophizing treatment: comparative efficacy & mechanisms (NIH R01). Development and implementation of an open-source learning healthcare system, CHOIR (http://choir/stanford.edu), to optimize pain care and innovative research in real-world patients.

  • Daniel V. Madison

    Daniel V. Madison

    Member, Wu Tsai Neurosciences Institute

    Current Research and Scholarly InterestsOur underlying forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression, and in particular the function and plasticity of Parvalbumin-containing interneurons in neocortex. In the past few years, we have used a combinatorial approach to comparing physiological and anatomical plasticity-induced changes in synapses using electrode recording and Array Tomography in the same neurons.

  • Merritt Maduke

    Merritt Maduke

    Professor of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsMolecular mechanisms of ion chnanels & transporters studied by integration of structural and electrophysiological methods.

  • Holden Maecker

    Holden Maecker

    Professor (Research) of Microbiology and Immunology

    Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.

  • Vinit B. Mahajan, MD, PhD

    Vinit B. Mahajan, MD, PhD

    Professor of Ophthalmology

    Current Research and Scholarly InterestsOur focus is the development of personalized medicine for eye diseases through translation of our discoveries in proteomics, genomics, and phenomics in humans, mice and tissue culture models.

  • Joshua Makower

    Joshua Makower

    Yock Family Professor and Professor of Bioengineering

    Current Research and Scholarly InterestsDr. Josh Makower is the Boston Scientific Applied Bioengineering Professor of Medicine and of Bioengineering at the Stanford University Schools of Medicine and Engineering and the Director of the Stanford Byers Center for Biodesign, the program he co-founded with Dr. Paul Yock twenty years ago. Josh helped create the fundamental structure of the Center’s core curriculum and is the chief architect of what is now called “The Biodesign Process.” Over the past 20 years since Josh and Paul founded Biodesign, this curriculum and the associated textbook has been used at Stanford and across the world to train hundreds of thousands of students, faculty and industry leaders on the Biodesign process towards the advancement of medical innovation for the improvement of patient care. Josh has practiced these same techniques directly as the Founder & Executive Chairman of ExploraMed, a medical device incubator, creating 9 companies since 1995. Transactions from the ExploraMed portfolio include NeoTract, acquired by Teleflex, Acclarent, acquired by J&J, EndoMatrix, acquired by C.R. Bard & TransVascular, acquired by Medtronic. Other ExploraMed/NEA ventures include Moximed, NC8 and Willow. Josh is also a Special Partner at NEA where he supports the healthcare team and medtech/healthtech investing practice. Josh serves on the boards of Allay Therapeutics, Revelle Aesthetics, Setpoint Medical, DOTS Technologies, Eargo, ExploraMed, Intrinsic Therapeutics, Moximed, Willow and Coravin. Josh holds over 300 patents and patent applications. He received an MBA from Columbia University, an MD from the NYU School of Medicine, a bachelor’s degree in Mechanical Engineering from MIT. Josh is a Member of the National Academy of Engineering and the College of Fellows of The American Institute for Medical and Biological Engineering and was awarded the Coulter Award for Healthcare Innovation by the Biomedical Engineering Society in 2018.

  • Robert Malenka

    Robert Malenka

    Nancy Friend Pritzker Professor of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsLong-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy.

  • Rachel Manber, PhD

    Rachel Manber, PhD

    Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)

    Current Research and Scholarly InterestsRecent and current projects include
    Treatment of insomnia during pregnancy
    Treatment of insomnia comorbid with sleep apnea
    Use of digital interventions for insomnia among middle age and older adults
    Mobile intervention for insomnia among those with alcohol use