Vice Provost and Dean of Research


Showing 91-95 of 95 Results

  • Carla Pugh, MD, PhD

    Carla Pugh, MD, PhD

    Thomas Krummel Professor

    Current Research and Scholarly InterestsThe Technology Enabled Clinical Improvement (T.E.C.I.) Center is a multidisciplinary team of researchers dedicated to the design and implementation of advanced engineering technologies that facilitate data acquisition relating to clinical performance.

  • Elisabetta Viani Puglisi

    Elisabetta Viani Puglisi

    Associate Professor (Research) of Structural Biology

    Current Research and Scholarly InterestsViral infections and subsequent host response depend on multiple RNA-protein interaction. My research focuses on the structural and functional characterization of RNA-protein complexes involved in viral infection. Current research aims to understand how the Human Immunodeficiency Virus (HIV) initiates its replication upon host infection. We use NMR spectroscopy and x-ray crystallography to study the structure of the initiation complex, formed by a host tRNA and HIV genomic RNA, coupled with biochemical and biophysical methods to understand functional properties. The goal of this research is to gain a molecular view of HIV replication initiation, and use this information to develop new therapeutic approaches to combat HIV.

  • Joseph (Jody) Puglisi

    Joseph (Jody) Puglisi

    Jauch Professor and Professor of Structural Biology

    Current Research and Scholarly InterestsThe Puglisi group investigates the role of RNA in cellular processes and disease. We investigate dynamics using single-molecule approaches. Our goal is a unified picture of structure, dynamics and function. We are currently focused on the mechanism and regulation of translation, and the role of RNA in viral infections. A long-term goal is to target processes involving RNA with novel therapeutic strategies.

  • Patrick Lee Purdon

    Patrick Lee Purdon

    Professor of Anesthesiology, Perioperative and Pain Medicine (Department Research) and, by courtesy, of Bioengineering

    BioMy research integrates neuroimaging, biomedical signal processing, and the systems neuroscience of general anesthesia and sedation.

    We are a neuroengineering lab focused on brain dynamics, brain health, and the neural mechanisms of anesthesia. Our research aims to understand the brain dynamics of aging, Alzheimer’s disease, child development, sleep, anesthesia, and consciousness. We use this knowledge to develop novel technologies for brain monitoring and physiological control. We also teach anesthesiologists how to use EEG to provide personalized anesthesia care.