Carl Preiksaitis

All Publications

• ChatGPT is not the solution to physicians' documentation burden. Nature medicine Preiksaitis, C., Sinsky, C. A., Rose, C. 2023

  View details for DOI 10.1038/s41591-023-02341-4

  View details for PubMedID 37169865

  View details for PubMedCentralID 7043175

• Teaching Principles of Medical Innovation and Entrepreneurship Through Hackathons: Case Study and Qualitative Analysis. JMIR medical education Preiksaitis, C., Dayton, J. R., Kabeer, R., Bunney, G., Boukhman, M. 2023; 9: e43916

  Abstract

  Innovation and entrepreneurship training are increasingly recognized as being important in medical education. However, the lack of faculty comfort with the instruction of these concepts as well as limited scholarly recognition for this work has limited the implementation of curricula focused on these skills. Furthermore, this lack of familiarity limits the inclusion of practicing physicians in health care innovation, where their experience is valuable. Hackathons are intense innovation competitions that use gamification principles to increase comfort with creative thinking, problem-solving, and interpersonal collaboration, but they require further exploration in medical innovation.To address this, we aimed to design, implement, and evaluate a health care hackathon with 2 main goals: to improve emergency physician familiarity with the principles of health care innovation and entrepreneurship and to develop innovative solutions to 3 discrete problems facing emergency medicine physicians and patients.We used previously described practices for conducting hackathons to develop and implement our hackathon (HackED!). We partnered with the American College of Emergency Physicians, the Stanford School of Biodesign, and the Institute of Design at Stanford (d.school) to lend institutional support and expertise in health care innovation to our event. We determined a location, time frame, and logistics for the competition and settled on 3 use cases for teams to work on. We planned to explore the learning experience of participants within a pragmatic paradigm and complete an abductive thematic analysis using data from a variety of sources.HackED! took place from October 1-3, 2022. In all, 3 teams developed novel solutions to each of the use cases. Our investigation into the educational experience of participants suggested that the event was valuable and uncovered themes suggesting that the learning experience could be understood within a framework from entrepreneurship education not previously described in relation to hackathons.Health care hackathons appear to be a viable method of increasing physician experience with innovation and entrepreneurship principles and addressing complex problems in health care. Hackathons should be considered as part of educational programs that focus on these concepts.

  View details for DOI 10.2196/43916

  View details for PubMedID 36826988

• Creating a Safe Space for Simulation: Is it Time to Stop Calling Them Confederates? Simulation in healthcare : journal of the Society for Simulation in Healthcare Preiksaitis, C. M., Lee, M. O., Schertzer, K. 2022

  Abstract

  Use of the term "confederate" is often used in research literature to describe an individual allied with the research team. Confederate is used in simulation research to describe participants allied with the simulation facilitator. Confederate can also refer to the Confederate States of America and has connotations of racial injustice and slavery. Use of this term in simulation may adversely affect psychological safety of learners. Use of the term within the literature is a potential driver of use during simulation sessions. We completed a rapid review of the health care simulation literature to determine the frequency of the term confederate. From 2000 to 2021, 2635 uses of confederate were identified in 765 articles. There seems to be an increased trend in use of this word. We argue that alternative terms exist and should be used to maximize psychological safety of learners.

  View details for DOI 10.1097/SIH.0000000000000710

  View details for PubMedID 36455290

• Reprint of: Approach to management of penetrating neck injuries: A case of multiple self-inflicted penetrating knife wounds. Disease-a-month : DM Liang, E., Preiksaitis, C., Wagner, A. M. 2022: 101422

  View details for DOI 10.1016/j.disamonth.2022.101422

  View details for PubMedID 35644650

• Identifying Social Media Competencies for Health Professionals: An International Modified Delphi Study to Determine Consensus for Curricular Design. Annals of emergency medicine Yilmaz, Y., Chan, T. M., Thoma, B., Luc, J. G., Haas, M., Preiksaitis, C., Tran, V., Gottlieb, M. 2022

  Abstract

  STUDY OBJECTIVE: The use of social media by health professionals is widespread. However, there is a lack of training to support the effective use of these novel platforms that account for the nuances of an effective health and research communication. We sought to identify the competencies needed by health care professionals to develop an effective social media presence as a medical professional, with the goal of building a social media curriculum.METHODS: We conducted a modified Delphi study, utilizing Kraiger's Knowledge, Skills, and Attitudes framework to identify appropriate items for inclusion in a social media curriculum targeted at health care professionals. Experts in this space were defined as health care professionals who had delivered workshops, published papers, or developed prominent social media tools/accounts. They were recruited through a multimodal campaign to complete a series of 3 survey rounds designed to build consensus. In keeping with prior studies, a threshold of 80% endorsement was used for inclusion in the final list of items.RESULTS: Ninety-eight participants met the expert criteria and were invited to participate in the study. Of the 98 participants, 92 (94%) experts completed the first round; of the 92 experts who completed the first round, 83 (90%) completed the second round; and of the 83 experts who completed the second round, 81 (98%) completed the third round of the Delphi study. Eighteen new items were suggested in the first survey and incorporated into the study. A total of 46 items met the 80% inclusion threshold.CONCLUSION: We identified 46 items that were believed to be important for health care professionals using social media. This list should inform the development of curricular activities and objectives.

  View details for DOI 10.1016/j.annemergmed.2022.02.016

  View details for PubMedID 35339286

• Symptomatic Respiratory Virus Infection and Chronic Lung Allograft Dysfunction. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Fisher, C. E., Preiksaitis, C. M., Lease, E. D., Edelman, J., Kirby, K. A., Leisenring, W. M., Raghu, G., Boeckh, M., Limaye, A. P. 2016; 62 (3): 313-319

  Abstract

  Chronic lung allograft dysfunction (CLAD) is a major cause of allograft loss post-lung transplantation. Prior studies have examined the association between respiratory virus infection (RVI) and CLAD were limited by older diagnostic techniques, study design, and case numbers. We examined the association between symptomatic RVI and CLAD using modern diagnostic techniques in a large contemporary cohort of lung transplant recipients (LTRs).We retrospectively assessed clinical variables including acute rejection, cytomegalovirus pneumonia, upper and lower RVI, and the primary endpoint of CLAD (determined by 2 independent reviewers) in 250 LTRs in a single university transplantation program. Univariate and multivariate Cox models were used to analyze the relationship between RVI and CLAD in a time-dependent manner, incorporating different periods of risk following RVI diagnosis.Fifty patients (20%) were diagnosed with CLAD at a median of 95 weeks post-transplantation, and 79 (32%) had 114 episodes of RVI. In multivariate analysis, rejection and RVI were independently associated with CLAD (adjusted hazard ratio [95% confidence interval]) 2.2 (1.2-3.9), P = .01 and 1.9 (1.1-3.5), P = .03, respectively. The association of RVI with CLAD was stronger the more proximate the RVI episode: 4.8 (1.9-11.6), P < .01; 3.4 (1.5-7.5), P < .01; and 2.4 (1.2-5.0), P = .02 in multivariate analysis for 3, 6, and 12 months following RVI, respectively.Symptomatic RVI is independently associated with development of CLAD, with increased risk at shorter time periods following RVI. Prospective studies to characterize the virologic determinants of CLAD and define the underlying mechanisms are warranted.

  View details for DOI 10.1093/cid/civ871

  View details for PubMedID 26565010

  View details for PubMedCentralID PMC4706632

• A patient self-collection method for longitudinal monitoring of respiratory virus infection in solid organ transplant recipients. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Preiksaitis, C. M., Kuypers, J. M., Fisher, C. E., Campbell, A. P., Jerome, K. R., Huang, M. L., Boeckh, M., Limaye, A. P. 2015; 62: 98-102

  Abstract

  Methods for the longitudinal study of respiratory virus infections are cumbersome and limit our understanding of the natural history of these infections in solid organ transplant (SOT) recipients.To assess the feasibility and patient acceptability of self-collected foam nasal swabs for detection of respiratory viruses in SOT recipients and to define the virologic and clinical course.We prospectively monitored the course of symptomatic respiratory virus infection in 18 SOT patients (14 lung, 3 liver, and 1 kidney) using patient self-collected swabs.The initial study sample was positive in 15 patients with the following respiratory viruses: rhinovirus (6), metapneumovirus (1), coronavirus (2), respiratory syncytial virus (2), parainfluenza virus (2), and influenza A virus (2). One hundred four weekly self-collected nasal swabs were obtained, with a median of 4 samples per patient (range 1-17). Median duration of viral detection was 21 days (range 4-77 days). Additional new respiratory viruses detected during follow-up of these 15 patients included rhinovirus (3), metapneumovirus (2), coronavirus (1), respiratory syncytial virus (1), parainfluenza virus (1), and adenovirus (1). Specimen collection compliance was good; 16/18 (89%) patients collected all required specimens and 79/86 (92%) follow-up specimens were obtained within the 7 ± 3 day protocol-defined window. All participants agreed or strongly agreed that the procedure was comfortable, simple, and 13/14 (93%) were willing to participate in future studies using this procedure.Self-collected nasal swabs provide a convenient, feasible, and patient-acceptable methodology for longitudinal monitoring of upper respiratory virus infection in SOT recipients.

  View details for DOI 10.1016/j.jcv.2014.10.021

  View details for PubMedID 25464966

  View details for PubMedCentralID PMC4629250

• Correspondence on the paper by Bridevaux et al. Thorax Preiksaitis, C. M., Limaye, A. P. 2014; 69 (1): 82

  View details for DOI 10.1136/thoraxjnl-2013-204610

  View details for PubMedID 24253835