Honors & Awards

  • Outstanding Internal Medicine Professional Research Award, University of California Davis (2018)
  • First Place Award, 11th Annual Spotlight on Junior Investigators Cancer Research Symposium, UC Davis Comprehensive Cancer Center (2017)
  • Graduate Research Grant, School of Veterinary Medicine, UC Davis (2016)
  • Graduate Fellowship, Integrative Pathobiology Graduate Group, UC Davis (2015)
  • Graduate Student Travel Award, UC Davis (2015)
  • Outstanding Poster Award, 6th Annual Lung Research Symposium, UC Davis (2015)
  • Scholarship Award, American Thoracic Society 2015 International Conference (2015)
  • Graduate Research Grant, School of Veterinary Medicine, UC Davis (2014)
  • Graduate Fellowship, Comparative Pathology Graduate Group, UC Davis (2013)
  • The Scholarship for Overseas Study, Ministry of Education, Taiwan (2012)

Professional Education

  • Doctor of Veterinary Medicine, National Chung Hsing University (1998)
  • Master of Science, National Chung Hsing University (2007)
  • Doctor of Philosophy, University of California Davis (2018)
  • Ph.D., University of California Davis (2018)

Stanford Advisors

Contact

  • Academic
    chuchiu@stanford.edu
    University - Scholar Department: Urology - Divisions Position: Postdoctoral Scholar

Additional Info

All Publications

  • Sialylated glycoproteins as biomarkers and drivers of progression in prostate cancer. Carbohydrate research Wen, R., Zhao, H., Zhang, D., Chiu, C., Brooks, J. D. 2022; 519: 108598

    Abstract

    Sialic acids have been implicated in cancer initiation, progression, and immune evasion in diverse human malignancies. Sialylation of terminal glycans on cell surface and secreted glycoproteins is a long-recognized feature of cancer cells. Recently, immune checkpoint inhibitor immunotherapy has tremendously improved the outcomes of patients with various cancers. However, available immunotherapy approaches have had limited efficacy in metastatic castration-resistant prostate cancer. Sialic acid modified glycoproteins in prostate cancers and their interaction with Siglec receptors on tumor infiltrating immune cells might underlie immunosuppressive signaling in prostate cancer. Here, we summarize the function of sialic acids and relevant glycosynthetic enzymes in cancer initiation and progression. We also discuss the possible uses of sialic acids as biomarkers in prostate cancer and the potential methods for targeting Siglec-sialic acid interactions for prostate cancer treatment.

    View details for DOI 10.1016/j.carres.2022.108598

    View details for PubMedID 35691122

https://orcid.org/0000-0001-7514-9676