Tom (Geonho) Park

All Publications

• Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch. Nature biotechnology Park, G., Bian, Y., Huang, H., Zhou, S., Qin, S., Lin, M., Yang, X., Lee, A., Ramkumar, A., Tome, M., Lander, J., Chen, X., Wang, S., Bheemreddy, P., Stanton, L., Sheng, R., Guo, G., Shehada, M., Wang, R., Roa, A., Lu, C., Yue, W., Wu, R. S., Gao, X., Hu, H., Yaghi, A., Liu, M., Impey, L., Collins, S. L., Papageorghiou, A. T., Laurent, L. C., Wear, K. A., Georgieva, A., Xu, S. 2026

  Abstract

  Ultrasonography is widely used for fetal monitoring but it requires sonographers and is limited to snapshot evaluations at discrete intervals. Here we report a wearable ultrasound patch (UPatch) for continuous and autonomous fetal monitoring. The UPatch can acquire anatomical structures and blood flow velocities, demonstrating good agreement with a handheld clinical ultrasound device on 62 pregnancies. Real-time image segmentation allows autonomous tracking of target vessels to acquire continuous blood flow spectra during fetal and maternal movements without a sonographer. Continuous monitoring data from 52 pregnant women aligned with stratified perinatal conditions, including healthy, small for gestational age, large for gestational age, gestational diabetes, preeclampsia and gestational hypertension. With further technology development, integration with a miniaturized circuit could enable fully wireless operation and greater user mobility. The UPatch could provide continuous assessment of fetal compromise in high-risk pregnancies, expanding prenatal-care capabilities.

  View details for DOI 10.1038/s41587-026-03140-1

  View details for PubMedID 42191988

• Integration of chemical and physical inputs for monitoring metabolites and cardiac signals in diabetes. Nature biomedical engineering Chang, A. Y., Lin, M., Yin, L., Reynoso, M., Ding, S., Liu, R., Dugas, Y., Casanova, A., Park, G., Li, Z., Luan, H., Askarinam, N., Zhang, F., Xu, S., Wang, J. 2025

  Abstract

  The development of closed-loop systems towards effective management of diabetes requires the inclusion of additional chemical and physical inputs that affect disease pathophysiology and reflect cardiovascular risks in patients. Comprehensive glycaemic control information should account for more than a single glucose signal. Here, we describe a hybrid flexible wristband sensing platform that integrates a microneedle array for multiplexed biomarker sensing and an ultrasonic array for blood pressure, arterial stiffness and heart-rate monitoring. The integrated system provides a continuous evaluation of the metabolic and cardiovascular status towards improving glycaemic control and alerting patients to cardiovascular risks. The multimodal platform offers continuous glucose, lactate and alcohol monitoring, along with simultaneous ultrasonic measurements of blood pressure, arterial stiffness and heart rate, to support understanding of the interplay between interstitial fluid biomarkers and physiological parameters during common activities. By expanding the continuous monitoring of patients with diabetes to additional biomarkers and key cardiac signals, our integrated multiplexed chemical-physical health-monitoring platform holds promise for addressing the limitations of existing single-modality glucose-monitoring systems towards enhanced management of diabetes and related cardiovascular risks.

  View details for DOI 10.1038/s41551-025-01439-z

  View details for PubMedID 40603746

  View details for PubMedCentralID 8126822