All Publications

  • Immunohistochemical and Histopathological Characterization of Spina Bifida Defect Tissues Removed After Prenatal and Postnatal Surgical Repair. Fetal and pediatric pathology Bardill, J. R., Laughter, M. R., Anderson, J. B., Hoffman, H., Gilani, A., Koster, M. I., Marwan, A. I. 2024: 1-9


    Background: Myelomeningocele or spina bifida is an open neural tube defect that is characterized by protrusion of the meninges and the spinal cord through a deformity in the vertebral arch and spinous process. Myelomeningocele of post-natal tissue is well described; however, pre-natal tissue of this defect has no known previous histologic characterization. We compared the histology of different forms of pre-natal myelomeningocele and post-natal myelomeningocele tissue obtained via prenatal intrauterine and postnatal surgical repairs. Methods: Pre-and post-natal tissues from spina bifida repair surgeries were obtained from lipomyelomeningocele, myeloschisis, and myelomeningocele spina bifida defects. Tissue samples were processed for H&E and immunohistochemical staining (KRT14 and p63) to assess epidermal and dermal development. Results: Prenatal skin near the defect site develops with normal epidermal, dermal, and adnexal structures. Within the grossly cystic specimens, histology shows highly dense fibrous connective tissue with complete absence of a normal epidermal development with a lack of p63 and KRT14 expression. Conclusion: Tissues harvested from prenatal and postnatal spina bifida repair surgeries appear as normal skin near the defect site. However, cystic tissues consist of highly dense fibrous connective tissue with complete absence of normal epidermal development.

    View details for DOI 10.1080/15513815.2024.2326834

    View details for PubMedID 38634787

  • Cutting edge: an analysis of United States patents for dermatologic surgery from 2012 to 2022 Anderson, J., Szeto, M., Rosander, A., Kang, J., Hamp, A., Anderson, J., Laughter, M. MOSBY-ELSEVIER. 2023: AB145
  • Sunless Tanners: An Analysis of Most Common Ingredients Hatch, J., Black, A., Laughter, M., Anderson, J. MOSBY-ELSEVIER. 2023: AB227
  • Skin Cancer, Climate Change, and Opportunities for Dermatologists CURRENT DERMATOLOGY REPORTS Flynn, M., Cooper, B. R., Rundle, C. W., Anderson, J., Laughter, M., Presley, C. L., Otchere, E., Stamey, C. 2023
  • Psychology of Aesthetics: Beauty, Social Media, and Body Dysmorphic Disorder. Clinics in dermatology Laughter, M. R., Anderson, J. B., Maymone, M. B., Kroumpouzos, G. 2023


    The perception of beauty is fluid within society and can morph based on cultural practices and societal interaction, such as social media exposure. The exposure to digital conference platforms has increased significantly, leading users to check their appearance constantly and find flaws in their perceived virtual appearance. Studies have shown that frequent social media use may lead to unrealistic body image ideals, a significant concern with appearance, and anxiety. Also, social media exposure can worsen body image dissatisfaction, social networking site addiction, and comorbidities of body dysmorphic disorder (BDD) such as depression and eating disorders. Additionally, excessive social media use can increase preoccupation with imagined image defects among BDD patients leading them to pursue minimally invasive cosmetic and plastic surgery procedures. This contribution aims to provide an overview of the evidence surrounding the perception of beauty, cultural aspects of aesthetics, and social media's consequences, especially on BDD's clinical specifics.

    View details for DOI 10.1016/j.clindermatol.2023.03.002

    View details for PubMedID 36882132

  • Utility of Interleukin-36 Immunohistochemical Staining to Differentiate Guttate Psoriasis and Pityriasis Rosea Anderson, J., Wang, L., Brown, R. ELSEVIER SCIENCE INC. 2023: S391
  • Telangiectasia-Related Social Media Posts: Cross-sectional Analysis of TikTok and Instagram. JMIR dermatology Diamond, C., Quinn, A. P., Presley, C. L., Jacobs, J., Laughter, M. R., Anderson, J., Rundle, C. 2023; 6: e41716

    View details for DOI 10.2196/41716

    View details for PubMedID 37632919

    View details for PubMedCentralID PMC10335132

  • Gua sha, Jade Roller, and Facial Massage: Are there benefits within Dermatology? Journal of cosmetic dermatology Hamp, A., Anderson, J., Laughter, M. R., Anderson, J. B., Presley, C. L., Rundle, C. W., Dellavalle, R. P. 2022

    View details for DOI 10.1111/jocd.15421

    View details for PubMedID 36170573

  • Altmetric scoring in dermatopathology: How do these high-scoring articles differ with other citation metrics? Anderson, J. B., Laughter, M. R., Saleem, A. MOSBY-ELSEVIER. 2022: AB16
  • Influence of Twitter on dermatopathology: What makes an influencer Anderson, J. B., Laughter, M. R., Presley, C. L., Gardner, J. M., High, W. MOSBY-ELSEVIER. 2022: AB176
  • Blockchain, Bitcoin, and Cryptocurrency: The new frontier within dermatology. Journal of the American Academy of Dermatology Anderson, J. B., Laughter, M. R. 2022

    View details for DOI 10.1016/j.jaad.2022.08.020

    View details for PubMedID 35987398

  • Top Skin-of-Color Publications in Dermatology. JMIR dermatology Cooper, B. R., Anderson, J. B., Laughter, M. R., Presley, C. L., Albrecht, J. M., Dellavalle, R. P. 2022; 5 (2): e37256

    View details for DOI 10.2196/37256

    View details for PubMedID 37632864

    View details for PubMedCentralID PMC10334886

  • Social Media as a Medium for Dermatologic Education. Current dermatology reports Cooper, B. R., Concilla, A., Albrecht, J. M., Bhukhan, A., Laughter, M. R., Anderson, J. B., Rundle, C. W., McEldrew, E. C., Presley, C. L. 2022: 1-7


    We explore the utility of social media platforms as educational tools in dermatology, providing a summary of how these sites are used by the public and dermatologists alike, and demonstrating ways these findings may be applied for educational purposes.Over half of the world's population utilizes social media platforms. More recently, these platforms have increasingly been used for educational purposes. In the field of dermatology, a large portion of the educational content is coming from users with no formal medical or dermatologic training.Each of the top five social media platforms in the world (Twitter, Instagram, TikTok, YouTube, and Facebook) has unique qualities which people may utilize to educate fellow users. As more of the population seeks online health information and education, it is important that dermatologists, while taking ethical considerations into account, become more comfortable facilitating educational content on social media.

    View details for DOI 10.1007/s13671-022-00359-4

    View details for PubMedID 35493063

    View details for PubMedCentralID PMC9036500

  • The Dermatologist on Social Media: When the Pros Outweigh the Cons. Comment on "Risks and Benefits of Using Social Media in Dermatology: Cross-sectional Questionnaire Study". JMIR dermatology Concilla, A., Laughter, M. R., Presley, C. L., Anderson, J., Rundle, C. W. 2022; 5 (1): e31943

    View details for DOI 10.2196/31943

    View details for PubMedID 37632875

    View details for PubMedCentralID PMC10334899

  • An Analysis of Sunscreen-Related Hashtags on Instagram. Photodermatology, photoimmunology & photomedicine Harp, T., Rundle, C. W., Anderson, J., Presley, C., Concilla, A., Laughter, M., Dellavalle, R. P. 1800

    View details for DOI 10.1111/phpp.12771

    View details for PubMedID 34984732

  • Type III Cutaneous Atypical Meningioma of the Scalp. Journal of cutaneous pathology Anderson, J. D., Anderson, J. B., Alhatem, A., Walter, A., Langston, L. 2022


    Cutaneous meningiomas can be a diagnostic challenge, as they are not only found very rarely in extracranial sites, including the skin, but also because of the histopathologic overlap with several other spindle cell tumors. Cutaneous meningiomas are divided into type I (congenital), type II (ectopic) and type III (via a direct extension) lesions. We present a rare case of atypical meningioma of the skin in a 71-year-old female. A patient presented with a painful and enlarging lesion on the left central frontal scalp. Biopsy showed bone and soft tissue with involvement of a spindle cell neoplasm, consisting of whorled nests with atypical features, including variably increased mitotic index, areas of hypercellularity, and sheeted architecture. The overall findings were consistent with an atypical meningioma (WHO grade 2). Atypical meningiomas constitute only 5 - 15% of all meningiomas. A skull MRI was later performed, which demonstrated a left frontal tumor consistent with an atypical meningioma that had eroded through the skull. Dermatopathologists should consider cutaneous meningioma as a differential diagnosis of spindle cell neoplasms of the skin and subcutaneous tissue in head and neck. This article is protected by copyright. All rights reserved.

    View details for DOI 10.1111/cup.14200

    View details for PubMedID 35001422

  • Social Media and Clinical Research in Dermatology. Current dermatology reports Geist, R., Militello, M., Albrecht, J. M., Presley, C. L., Anderson, J. B., Laughter, M., Rundle, C. W. 2021: 1-7


    The immense growth of social media has afforded new opportunities in dermatology clinical research. This review serves to outline how social media has impacted clinical research and to explore future avenues for which social media can make a significant impact in dermatology clinical research.Recent clinical trials augmented by social media have demonstrated increased participant enrollment, shortened recruitment timelines, and decreased recruitment cost. The incorporation of social media into clinical research has also afforded greater access to teledermatology and the initiation of virtual clinical trials.Clinical research serves as a primary source of evidence for refining healthcare practices by expanding the understanding of patient demographics, methods for improving patient care, and new therapeutic discoveries. Since its initiation, social media has played an integral and ever-expanding role in clinical research.

    View details for DOI 10.1007/s13671-021-00350-5

    View details for PubMedID 34840860

    View details for PubMedCentralID PMC8603896

  • Social Media and Ethical Challenges for the Dermatologist CURRENT DERMATOLOGY REPORTS Militello, M., Yang, R. A., Anderson, J. B., Szeto, M. D., Presley, C. L., Laughter, M. R. 2021: 1-8


    The purpose of review is to provide guidance on the use of social media within the context of dermatology and discuss its ethical, professional, and legal implications in education, mentorship, networking, business, and clinical settings.Despite its fundamental value as a means of communication and knowledge sharing, social media carries legal, ethical, and professional challenges. Healthcare providers have run into issues such as misinformation, conflicts of interest, and overstepping patient-physician boundaries when using social media. An interesting finding is that dermatologists commonly engage with an online audience through social media marketing or being an influencer to improve business and extend their reach to clients; however, this warrants formal training and the need to monitor their own online presence to prevent legal consequences.Social media has become integral in everyday life; billions of people now receive information and stay connected with each other through social platforms. Within medicine, social media has enhanced various aspects of healthcare, such as professional networking, patient care, and patient education. In dermatology, social media allows dermatologists to promote their businesses and services through patient testimonials, posting advice on blogs, and networking with a large audience of potential patients. However, having a social media presence must be exercised with care, purpose, and transparency to maximize benefits and minimize harmful consequences. This is especially important when inappropriate social media posts by physicians can be scrutinized for breaching patient confidentiality, violating privacy, financial conflicts of interest, and possibly disseminating incorrect information.

    View details for DOI 10.1007/s13671-021-00340-7

    View details for Web of Science ID 000695481000001

    View details for PubMedID 34540357

    View details for PubMedCentralID PMC8435566

  • Indoor tanning: Evidence surrounding advertised health claims CLINICS IN DERMATOLOGY Laughter, M. R., Anderson, J. B., Aguilera, M. N., Sadeghpour, M., Pugliano-Mauro, M. 2021; 39 (5): 865-872


    Indoor tanning continues to remain common, despite evidence of an increased risk of skin cancer from artificial ultraviolet (UV) radiation. In the hopes of gaining customers, the tanning bed industry has marketed health benefits of indoor tanning such as increased vitamin D production, development of a base tan, enhanced mood, and treatment of certain dermatologic conditions. To better educate their patients, providers need a comprehensive reference reviewing the evidence that support or oppose these claims. In this work, we conducted an evidence-based review of the literature to identify and grade studies that investigate health claims related to UV exposure. Results indicate that there is little evidence to support each of these proposed health benefits. Tanning beds emit primarily UVA radiation, which is relatively ineffective at activating vitamin D or mood enhancing pathways, and the effects are minimal in regard to tanning beds generating a protective base tan or treating dermatologic conditions compared with the increased risk of skin cancer. Health care providers must continue to warn and educate patients about the misleading information propagated by the tanning bed industry as well as about the dangers of artificial UV radiation.

    View details for DOI 10.1016/j.clindermatol.2021.08.015

    View details for Web of Science ID 000719473300014

    View details for PubMedID 34785014

  • Usage and engagement with Instagram by dermatology residency programs during the COVID-19 pandemic compared with Twitter and Facebook. Journal of the American Academy of Dermatology Harp, T., Szeto, M. D., Presley, C. L., Meckley, A. L., Geist, R., Anderson, J., Laughter, M. R., Rundle, C. W., Husayn, S. S., Dellavalle, R. P. 2021

    View details for DOI 10.1016/j.jaad.2021.05.071

    View details for PubMedID 34418516

  • Commonly Used Over the Counter Therapies for Hair Growth in Skin of Color: An Evidence-Based Review JOURNAL OF DRUGS IN DERMATOLOGY Laughter, M. R., Anderson, J. B., Ugonabo, N., Mohammodu, Z., Sadeghpour, M., Shapiro, J., Lo Sicco, K. 2021; 20 (7): 726-731


    Given the immense psychosocial effects of hair loss as well as patient preference for treatment type, it is common for patients to turn to alternative medicine to improve their conditions. However, the commonly used alternative treatments can vary greatly between patients and particularly among skin of color populations.In this work, we performed a scoping review of the evidence behind alternative topical treatments for hair loss used by skin of color patients. Methods & Materials: We conducted a comprehensive search using PubMed to identify relevant studies.Results show a diverse variety of hair growth products used; however, only a few are supported by randomized controlled trials, case reports, pilot studies, and animal studies with some important limitations.This information will be exceedingly useful for physicians so they may relay accurate evidence on these haircare practices to their skin of color patients. J Drugs Dermatol. 2021;20(7):726-731. doi:10.36849/JDD.5689.

    View details for DOI 10.36849/JDD.5689

    View details for Web of Science ID 000677732600002

    View details for PubMedID 34231986

  • Emerging topical therapies to treat pigmentary disorders: an evidence-based approach JOURNAL OF DERMATOLOGICAL TREATMENT Hu, S., Laughter, M. R., Anderson, J. B., Sadeghpour, M. 2021: 1-7


    Hyperpigmentation disorders are commonly encountered in dermatology clinics. The use of prescription-grade and over-the-counter topical lightening agents has increased in popularity, leading to a substantial growth of research over the past decade.We seek to review clinical studies evaluating the use of different Rx-grade and OTC ingredients in treating hyperpigmentation.A comprehensive search on PubMed was conducted to identify patient-based evidence on the most common ingredients used as topical lightening agents: arbutin, ascorbic acid, cysteamine, hydroquinone, kojic acid, niacinamide, retinoids, and triple-combination therapy. The topicals were classified as either prescription-grade or over-the-counter.Varying levels of evidence support the use of topicals in treating hyperpigmentation. There were more clinical trials examining Rx-grade products than OTC products. Mild but tolerated side effects are noted in many of these agents.Careful monitoring and adjustment of doses will be needed to maximize skin lightening benefits and minimize side effects.

    View details for DOI 10.1080/09546634.2021.1940811

    View details for Web of Science ID 000665718000001

    View details for PubMedID 34114938

  • Scoping Review of Therapeutic Strategies for Keloids and Hypertrophic Scars PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN Anderson, J. B., Foglio, A., Harrant, A. B., Huang, C. A., Hultman, C., Mathes, D. W., Chong, T. W. 2021; 9 (3): e3469


    Keloids are an abnormal proliferation of scars that can involve large areas of tissue beyond the original injury site. Hypertrophic scars are similar clinically, but do not exceed the original scar limits. These scarring abnormalities can cause noxious symptoms such as pain, tenderness, itching, and ulcerations. The aim of this review is to discuss current therapies for both types of abnormal scarring, and to determine if guidelines can be provided for excisional treatment with adjuvant therapies versus non-excisional methods.A systematic literature search was performed through the Web of Science database. The search revolved around keywords such as "keloid," "hypertrophic scars," and "treatment." Articles were reviewed and screened for inclusion and exclusion criteria. The review focuses on an analysis and summarization of randomized control trials regarding keloid or hypertrophic scar treatments.The original searches produced 1161 and 1275 articles for keloid and hypertrophic scars, respectively. In total, 316 duplicates were found. After accounting for 2014-2019 publication time, 655 keloid and 893 hypertrophic scar articles were reviewed. This resulted in 15 articles that pertained to treatment and randomized control trials.Keloids and hypertrophic scars present a clinical challenge. Based on qualitative review of recurrence, neither excision plus adjuvant therapy or nonsurgical treatments can be recommended preferentially at this time. More research is needed to determine if recurrence rate bias exists between the treatment regimens, as excisional treatment plus adjuvant therapy is reserved for refractory scars.

    View details for DOI 10.1097/GOX.0000000000003469

    View details for Web of Science ID 000639595600028

    View details for PubMedID 33786262

    View details for PubMedCentralID PMC7994010

  • Comorbidities and health care systems differences among states as it relates to COVID-19 JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE Anderson, J. B., Laughter, M. R., Nguyen, A., Erlandson, K. M. 2021; 5 (1)
  • From the Cochrane Library: Probiotics for Treating Eczema. Journal of the American Academy of Dermatology Szeto, M. D., Hassan, S., Hamp, A., Anderson, J., Sivesind, T. E., Anderson, J. B., Laughter, M. R., Makrygeorgou, A., Boyle, R. J., Dellavalle, R. P. 2021

    View details for DOI 10.1016/j.jaad.2021.10.032

    View details for PubMedID 34748863

  • Biomimetic scaffold for efficient in vitro skin engineering Laughter, M., Anderson, J. B., Bardill, J. R., Marwan, R., Park, D. MOSBY-ELSEVIER. 2020: AB109
  • Changes to Venous Flow Coupler Signal during DIEP Flap Inset Can Be Predictive of Poor Clinical Outcomes in Autologous Breast Reconstruction JOURNAL OF RECONSTRUCTIVE MICROSURGERY Colakoglu, S., Johnson, A., Anderson, J., Mathes, D., Chong, T. 2020; 36 (6): 466-470


     Venous flow couplers are typically used to monitor free flaps during the postoperative period, with a continuous venous signal available immediately after completion of the anastomosis. Intraoperative loss of the coupler signal is not uncommon and may require adjustments in free flap inset and even flap thickness to get the venous signal to return. The effects of intraoperative coupler signal loss and the role of this technology on flap outcomes have not been evaluated. We hypothesized that the use of intraoperative coupler can be protective of both early and late flap complications by preventing unfavorable flap insets. All patients who underwent free flap breast reconstruction between January 2018 and June 2019 by single microsurgery team were included. Flap inset and inset changes based on flow coupler signal problems were reviewed in the procedure notes. Patient demographics data and clinical outcomes were analyzed with comprehensive chart review. Forty-four consecutive patients with 69 free flaps were identified. There were no significant differences in patient characteristics or venous coupler size used in venous anastomosis. Although the number of operating room take backs for venous insufficiency was not significantly different between two groups, the free flaps with inset change had significantly higher complications that required later surgical intervention (p = 0.0464). Surgeons should be aware that intraoperative coupler signal loss can be associated with poor clinical outcomes postoperatively and these flaps may require more perfusion imaging, flap debulking, or even additional venous anastomosis.

    View details for DOI 10.1055/s-0040-1703014

    View details for Web of Science ID 000541964000011

    View details for PubMedID 32172526

  • Characterization of immune cells found in keloid versus normal skin tissue Anderson, J. B., Harrant, A. B., Navarro-Alvarez, N., Wang, Z., van Bokhoven, A., High, W., Chong, T. W., Huang, C. A. AMER ASSOC IMMUNOLOGISTS. 2020
  • Unattainable Standards of Beauty: Temporal Trends of Victoria's Secret Models from 1995 to 2018 AESTHETIC SURGERY JOURNAL Maymone, M. C., Laughter, M., Anderson, J. B., Secemsky, E. A., Vashi, N. A. 2020; 40 (2): NP72-NP76

    View details for DOI 10.1093/asj/sjz271

    View details for Web of Science ID 000515092700005

    View details for PubMedID 31872253

  • Synthetic investigations of 3,4-dihydroquinoxalin-2(1H)-one and quinoxalin-2(1H)-one under varied experimental conditions Kurttila, J., Emery, T., Kellen-Yuen, C. AMER CHEMICAL SOC. 2015