Jennifer Mattler Guzman
Industrial Hygienist/Chemical Hygiene Officer, Environmental Health and Safety (EH&S)
All Publications
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A Laboratory Accident of Acryloyl Chloride, Its Consequences, Treatment, and Safety Measures: An Arduous Lesson to All Researchers (vol 29, pg 405, 2022)
ACS CHEMICAL HEALTH & SAFETY
2023: 98-99
View details for DOI 10.1021/acs.chas.3c00019
View details for Web of Science ID 000960510300001
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Studies on the regio- and diastereo-selective epoxidation of daphnanes and tiglianes
TETRAHEDRON LETTERS
2015; 56 (23): 3423-3427
Abstract
Daphnanes and tiglianes are diterpenes with a shared tricyclic 5-7-6 ring system. Many members exhibit significant biological activities often associated with protein kinase C signaling. Many of these natural products (~100) have a C6-C7 α-epoxide whose influence on biological activity is little studied. Using the more readily available phorbol ester PDBu as a test substrate, we report an efficient, and potentially general, α-epoxidation method based on a vanadium-catalyzed asymmetric epoxidation with bishydroxamic acid (BHA) ligands.
View details for DOI 10.1016/j.tetlet.2015.01.126
View details for Web of Science ID 000356544800113
View details for PubMedCentralID PMC4449265