All Publications

  • A Laboratory Accident of Acryloyl Chloride, Its Consequences, Treatment, and Safety Measures: An Arduous Lesson to All Researchers (vol 29, pg 405, 2022) ACS CHEMICAL HEALTH & SAFETY Reidy, J., Guzman, J., Vleck, S., Ahmad, I., Patel, H. 2023: 98-99
  • Studies on the regio- and diastereo-selective epoxidation of daphnanes and tiglianes TETRAHEDRON LETTERS Boudreault, P., Mattler, J. K., Wender, P. A. 2015; 56 (23): 3423-3427


    Daphnanes and tiglianes are diterpenes with a shared tricyclic 5-7-6 ring system. Many members exhibit significant biological activities often associated with protein kinase C signaling. Many of these natural products (~100) have a C6-C7 α-epoxide whose influence on biological activity is little studied. Using the more readily available phorbol ester PDBu as a test substrate, we report an efficient, and potentially general, α-epoxidation method based on a vanadium-catalyzed asymmetric epoxidation with bishydroxamic acid (BHA) ligands.

    View details for DOI 10.1016/j.tetlet.2015.01.126

    View details for Web of Science ID 000356544800113

    View details for PubMedCentralID PMC4449265