Kajal Khanna

All Publications

• Analysis of guideline recommendations for treatment of asthma exacerbations in children: a Pediatric Emergency Research Networks (PERN) study. Archives of disease in childhood Craig, S., Collings, M., Gray, C., Benito, J., Velasco, R., Lyttle, M. D., Roland, D., Schuh, S., Shihabuddin, B., Kwok, M., Mahajan, P., Johnson, M., Zorc, J., Khanna, K., Fernandes, R., Yock-Corrales, A., Santhanam, I., Cheema, B., Ong, G. Y., Jaiganesh, T., Powell, C., Nixon, G., Dalziel, S., Babl, F. E., Graudins, A. 2024

  Abstract

  There is significant practice variation in acute paediatric asthma, particularly severe exacerbations. It is unknown whether this is due to differences in clinical guidelines.To describe and compare the content and quality of clinical guidelines for the management of acute exacerbations of asthma in children between geographic regions.Observational study of guidelines for the management of acute paediatric asthma from institutions across a global collaboration of six regional paediatric emergency research networks.158 guidelines were identified. Half provided recommendations for at least two age groups, and most guidelines provided treatment recommendations according to asthma severity.There were consistent recommendations for the use of inhaled short-acting beta-agonists and systemic corticosteroids. Inhaled anticholinergic therapy was recommended in most guidelines for severe and critical asthma, but there were inconsistent recommendations for its use in mild and moderate exacerbations. Other inhaled therapies such as helium-oxygen mixture (Heliox) and nebulised magnesium were inconsistently recommended for severe and critical illness.Parenteral bronchodilator therapy and epinephrine were mostly reserved for severe and critical asthma, with intravenous magnesium most recommended. There were regional differences in the use of other parenteral bronchodilators, particularly aminophylline.Guideline quality assessment identified high ratings for clarity of presentation, scope and purpose, but low ratings for stakeholder involvement, rigour of development, applicability and editorial independence.Current guidelines for the management of acute paediatric asthma exacerbations have substantial deficits in important quality domains and provide limited and inconsistent guidance for severe exacerbations.

  View details for DOI 10.1136/archdischild-2023-326739

  View details for PubMedID 38325912

• Implementation of a pediatric in situ, train-the-trainer simulation program in general emergency departments. AEM education and training Schertzer, K., Wang, N. E., Khanna, K., Lee, M. O. 2023; 7 (1): e10843

  Abstract

  Background: Most children receive emergency care in general emergency departments (EDs). Pediatric resuscitations require specific equipment and weight-based dosing that may be less familiar to general ED healthcare professionals. In situ simulation (ISS) improves teamwork and problem solving, and it may identify latent safety threats. This innovative program brought academic faculty to participating hospitals and taught simulation principles in a small-group environment. This format removed many of the barriers to implementing simulations for general EDs and was intended to teach principles for utilizing simulation to meet unique departmental needs.Methods: Using the Consolidated Framework for Implementation Research (CFIR) framework, ED teams at eight hospitals participated in a train-the-trainer program from 2016 to 2020intended to help them implement their own ISSs. Training covered benefits of ISS, use of simulation for identifying latent safety threats, debriefing principles, and potential safety risks of ISS. Faculty also provided on-site mentoring during the implementation phase. We identified factors and barriers that contributed to the successful adoption of an ISS program.Results: Most hospitals continued their ISS program after the study ended. Several themes emerged as pearls and pitfalls to implementing a train-the-trainer program. Successful teams had strong nursing and physician leadership participation, and team members had positive working relationships with early positive feedback which encouraged future ISS implementation. Barriers to simulation included high staff turnover of nurses and physicians as well as social distancing protocols related to infection control.Conclusions: Academic EDs can partner with general EDs to implement a train-the-trainer simulation program. We describe facilitators and barriers to implementing a train-the-trainer ISS program in general EDs to improve emergency care for high-risk, low-frequency events.

  View details for DOI 10.1002/aet2.10843

  View details for PubMedID 36743260

• Race, Racism and Antiracism in Emergency Medicine: A Scoping Review of the Literature and Research Agenda for the Future. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Darby, A., Cleveland Manchanda, E. C., Janeway, H., Samra, S., Hicks, M. N., Long, R., Gipson, K. A., Chary, A. N., Adjei, B. A., Khanna, K., Pierce, A., Kaltiso, S. O., Spadafore, S., Tsai, J., Dekker, A., Thiessen, M. E., Foster, J., Diaz, R., Mizuno, M., Schoenfeld, E. 2022

  Abstract

  STUDY OBJECTIVES: To conduct a scoping review of the literature and develop consensus-derived research priorities for future research inquiry in an effort to 1) identify and summarize existing research related to race, racism and antiracism in emergency medicine (EM) and adjacent fields, and 2) set the agenda for EM research in these topic areas.METHODS: A scoping review of the literature using PubMed and EMBASE databases, as well as review of citations from included articles, formed the basis for discussions with community stakeholders, who in turn helped to inform and shape the discussion and recommendations of participants in the Society for Academic Emergency Medicine (SAEM) Consensus Conference. Through electronic surveys and two virtual meetings held in April 2021, consensus was reached on terminology, language and priority research questions, which were rated on importance or impact (highest, medium, lower), and feasibility or ease of answering (easiest, moderate, difficult).RESULTS: A total of 344 articles were identified through the literature search, of which 187 met inclusion criteria; an additional 34 were identified through citation review. Findings of racial inequities in EM and related fields were grouped in 28 topic areas, from which emerged 44 key research questions. A dearth of evidence for interventions to address manifestations of racism in EM was noted throughout.CONCLUSIONS: Evidence of racism in EM emerged in nearly every facet of our literature. Key research priorities identified through consensus processes provide a roadmap for addressing and eliminating racism and other systems of oppression in emergency medicine.

  View details for DOI 10.1111/acem.14601

  View details for PubMedID 36200540

• Omphalitis and Concurrent Serious Bacterial Infection. Pediatrics Kaplan, R. L., Cruz, A. T., Freedman, S. B., Smith, K., Freeman, J., Lane, R. D., Michelson, K. A., Marble, R. D., Middelberg, L. K., Bergmann, K. R., McAneney, C., Noorbakhsh, K. A., Pruitt, C., Shah, N., Badaki-Makun, O., Schnadower, D., Thompson, A. D., Blackstone, M. M., Abramo, T. J., Srivastava, G., Avva, U., Samuels-Kalow, M., Morientes, O., Kannikeswaran, N., Chaudhari, P. P., Strutt, J., Vance, C., Haines, E., Khanna, K., Gerard, J., Bajaj, L. 2022

  Abstract

  OBJECTIVE: Describe the clinical presentation, prevalence of concurrent serious bacterial infection (SBI), and outcomes among infants with omphalitis.METHODS: Within the Pediatric Emergency Medicine Collaborative Research Committee, 28 sites reviewed records of infants ≤90 days of age with omphalitis seen in the emergency department from January 1, 2008, to December 31, 2017. Demographic, clinical, laboratory, treatment, and outcome data were summarized.RESULTS: Among 566 infants (median age 16 days), 537 (95%) were well-appearing, 64 (11%) had fever at home or in the emergency department, and 143 (25%) had reported fussiness or poor feeding. Blood, urine, and cerebrospinal fluid cultures were collected in 472 (83%), 326 (58%), and 222 (39%) infants, respectively. Pathogens grew in 1.1% (95% confidence interval [CI], 0.3%-2.5%) of blood, 0.9% (95% CI, 0.2%-2.7%) of urine, and 0.9% (95% CI, 0.1%-3.2%) of cerebrospinal fluid cultures. Cultures from the site of infection were obtained in 320 (57%) infants, with 85% (95% CI, 80%-88%) growing a pathogen, most commonly methicillin-sensitive Staphylococcus aureus (62%), followed by methicillin-resistant Staphylococcus aureus (11%) and Escherichia coli (10%). Four hundred ninety-eight (88%) were hospitalized, 81 (16%) to an ICU. Twelve (2.1% [95% CI, 1.1%-3.7%]) had sepsis or shock, and 2 (0.4% [95% CI, 0.0%-1.3%]) had severe cellulitis or necrotizing soft tissue infection. There was 1 death. Serious complications occurred only in infants aged <28 days.CONCLUSIONS: In this multicenter cohort, mild, localized disease was typical of omphalitis. SBI and adverse outcomes were uncommon. Depending on age, routine testing for SBI is likely unnecessary in most afebrile, well-appearing infants with omphalitis.

  View details for DOI 10.1542/peds.2021-054189

  View details for PubMedID 35441224

• Guiding Fellows to Independent Practice: Current Trends in Pediatric Emergency Medicine Fellow Supervision. Pediatric emergency care Kou, M., Baghdassarian, A., Khanna, K., Jamal, N., Carney, M., Fein, D. M., Kim, I., Langhan, M. L., Rose, J. A., Zuckerbraun, N. S., Roskind, C. G., AAP Section on Emergency Medicine Fellowship Program Director's Committee 2022

  Abstract

  BACKGROUND: Recent studies highlight the importance of physician readiness to practice beyond graduate training. The Accreditation Council for Graduate Medical Education mandates that pediatric emergency medicine (PEM) fellows be prepared for independent practice by allowing "progressive responsibility for patient care." Prior unpublished surveys of program directors (PDs) indicate variability in approaches to provide opportunities for more independent practice during fellowship training.OBJECTIVES: The aims of the study were to describe practices within PEM fellowship programs allowing fellows to work without direct supervision and to identify any barriers to independent practice in training.DESIGN/METHODS: An anonymous electronic survey of PEM fellowship PDs was performed. Survey items were developed using an iterative modified Delphi process and pilot tested. Close-ended survey responses and demographic variables were summarized with descriptive statistics. Responses to open-ended survey items were reviewed and categorized by theme.RESULTS: Seventy two of 84 PDs (88%) responded to the survey; however, not all surveys were completed. Of the 68 responses to whether fellows could work without direct supervision (as defined by the Accreditation Council for Graduate Medical Education) during some part of their training, 31 (45.6%) reported that fellows did have this opportunity. In most programs, clinical independence was conditional on specific measures including the number of clinical hours completed, milestone achievement, and approval by the clinical competency committee. Reported barriers to fellow practice without direct oversight included both regulatory and economic constraints.CONCLUSIONS: Current training practices that provide PEM fellows with conditional clinical independence are variable. Future work should aim to determine best practices of entrustment, identify ideal transition points, and mitigate barriers to graduated responsibility.

  View details for DOI 10.1097/PEC.0000000000002676

  View details for PubMedID 35353795

• The Path Forward: Using Metrics to Promote Equitable Work Environments. Pediatrics Cansino, C., Khanna, K., Johnson Bhembe, X., Overholser, B., Burstin, H. R., Spector, N. D. 2021; 148 (Suppl 2)

  Abstract

  Women continue to be underrepresented in medicine, especially in senior leadership positions, and they experience challenges related to gender bias and sexual harassment. Women who are members of multiple groups that experience marginalization, including, for example, women who are American Indian, Alaskan native, indigenous, Black, or Hispanic, face a compounded challenge. In this article, we explore how institutions and professional organizations in medicine can use metrics to better understand the structural disparities that create and promote gender inequity in the work environment and how to employ these metrics to track progress in narrowing these gaps. Examples in health care (clinical medicine, scientific organizations, scientific publishing), business, and law are used to illustrate how impactful metrics can promote accountability when coupled with transparent reporting.

  View details for DOI 10.1542/peds.2021-051440G

  View details for PubMedID 34873627

• The Path Forward: Using Metrics to Promote Equitable Work Environments. Pediatrics Cansino, C., Khanna, K., Johnson Bhembe, X., Overholser, B., Burstin, H. R., Spector, N. D. 2021; 148 (Suppl 2)

  Abstract

  Women continue to be underrepresented in medicine, especially in senior leadership positions, and they experience challenges related to gender bias and sexual harassment. Women who are members of multiple groups that experience marginalization, including, for example, women who are American Indian, Alaskan native, indigenous, Black, or Hispanic, face a compounded challenge. In this article, we explore how institutions and professional organizations in medicine can use metrics to better understand the structural disparities that create and promote gender inequity in the work environment and how to employ these metrics to track progress in narrowing these gaps. Examples in health care (clinical medicine, scientific organizations, scientific publishing), business, and law are used to illustrate how impactful metrics can promote accountability when coupled with transparent reporting.

  View details for DOI 10.1542/peds.2021-051440G

  View details for PubMedID 34470882

• Neonatal Mastitis and Concurrent Serious Bacterial Infection. Pediatrics Kaplan, R. L., Cruz, A. T., Michelson, K. A., McAneney, C., Blackstone, M. M., Pruitt, C. M., Shah, N., Noorbakhsh, K. A., Abramo, T. J., Marble, R. D., Middelberg, L., Smith, K., Kannikeswaran, N., Schnadower, D., Srivastava, G., Thompson, A. D., Lane, R. D., Freeman, J. F., Bergmann, K. R., Morientes, O., Gerard, J., Badaki-Makun, O., Avva, U., Chaudhari, P. P., Freedman, S. B., Samuels-Kalow, M., Haines, E., Strutt, J., Khanna, K., Vance, C., Bajaj, L. 2021

  Abstract

  OBJECTIVES: Describe the clinical presentation, prevalence, and outcomes of concurrent serious bacterial infection (SBI) among infants with mastitis.METHODS: Within the Pediatric Emergency Medicine Collaborative Research Committee, 28 sites reviewed records of infants aged ≤90 days with mastitis who were seen in the emergency department between January 1, 2008, and December 31, 2017. Demographic, clinical, laboratory, treatment, and outcome data were summarized.RESULTS: Among 657 infants (median age 21 days), 641 (98%) were well appearing, 138 (21%) had history of fever at home or in the emergency department, and 63 (10%) had reported fussiness or poor feeding. Blood, urine, and cerebrospinal fluid cultures were collected in 581 (88%), 274 (42%), and 216 (33%) infants, respectively. Pathogens grew in 0.3% (95% confidence interval [CI] 0.04-1.2) of blood, 1.1% (95% CI 0.2-3.2) of urine, and 0.4% (95% CI 0.01-2.5) of cerebrospinal fluid cultures. Cultures from the site of infection were obtained in 335 (51%) infants, with 77% (95% CI 72-81) growing a pathogen, most commonly methicillin-resistant Staphylococcus aureus (54%), followed by methicillin-susceptible S aureus (29%), and unspecified S aureus (8%). A total of 591 (90%) infants were admitted to the hospital, with 22 (3.7%) admitted to an ICU. Overall, 10 (1.5% [95% CI 0.7-2.8]) had sepsis or shock, and 2 (0.3% [95% CI 0.04-1.1]) had severe cellulitis or necrotizing soft tissue infection. None received vasopressors or endotracheal intubation. There were no deaths.CONCLUSIONS: In this multicenter cohort, mild localized disease was typical of neonatal mastitis. SBI and adverse outcomes were rare. Evaluation for SBI is likely unnecessary in most afebrile, well-appearing infants with mastitis.

  View details for DOI 10.1542/peds.2021-051322

  View details for PubMedID 34187909

• Protecting the emergency physician workforce during the coronavirus disease 2019 pandemic through precision scheduling at an academic tertiary care trauma center. Journal of the American College of Emergency Physicians open Lee, M. O., Ribeira, R., Fang, A., Cantwell, L., Khanna, K., Smith, C., Gharahbaghian, L. 2021; 2 (1): e12221

  Abstract

  The coronavirus disease 2019 (COVID-19) pandemic created new emergency physician staffing challenges. Emergency physicians may be taken out of the workforce because of respiratory symptoms or pending severe acute respiratory syndrome coronavirus 2 test results. Vulnerable emergency physician populations with increased risk of serious disease and death from COVID-19 include physicians at older ages; those with chronic medical conditions, including cardiac and pulmonary diseases and immunosuppression; and potentially pregnancy. We present our approach to planning for staffing issues through precision scheduling. We describe the actions taken to protect our vulnerable physicians and maximize our physician coverage. Measures include optimizing workforce; increasing backup call system; adjusting shifts based on patient arrival times, volume, and surge predictions; minimizing exposure to COVID-19 and reduce personal protective equipment use through telemedicine, huddles, and, creating lower risk emergency department care areas; and standardizing intubations to limit exposure.

  View details for DOI 10.1002/emp2.12221

  View details for PubMedID 33615307

• Invasive Bacterial Infections in Afebrile Infants Diagnosed With Acute Otitis Media. Pediatrics McLaren, S. H., Cruz, A. T., Yen, K., Lipshaw, M. J., Bergmann, K. R., Mistry, R. D., Gutman, C. K., Ahmad, F. A., Pruitt, C. M., Thompson, G. C., Steimle, M. D., Zhao, X., Schuh, A. M., Thompson, A. D., Hanson, H. R., Ulrich, S. L., Meltzer, J. A., Dunnick, J., Schmidt, S. M., Nigrovic, L. E., Waseem, M., Velasco, R., Ali, S., Cullen, D. L., Gomez, B., Kaplan, R. L., Khanna, K., Strutt, J., Aronson, P. L., Taneja, A., Sheridan, D. C., Chen, C. C., Bogie, A. L., Wang, A., Dayan, P. S., PEDIATRIC EMERGENCY MEDICINE COLLABORATIVE RESEARCH COMMITTEE 2020

  Abstract

  OBJECTIVES: To determine the prevalence of invasive bacterial infections (IBIs) and adverse events in afebrile infants with acute otitis media (AOM).METHODS: We conducted a 33-site cross-sectional study of afebrile infants ≤90 days of age with AOM seen in emergency departments from 2007 to 2017. Eligible infants were identified using emergency department diagnosis codes and confirmed by chart review. IBIs (bacteremia and meningitis) were determined by the growth of pathogenic bacteria in blood or cerebrospinal fluid (CSF) culture. Adverse events were defined as substantial complications resulting from or potentially associated with AOM. We used generalized linear mixed-effects models to identify factors associated with IBI diagnostic testing, controlling for site-level clustering effect.RESULTS: Of 5270 infants screened, 1637 met study criteria. None of the 278 (0%; 95% confidence interval [CI]: 0%-1.4%) infants with blood cultures had bacteremia; 0 of 102 (0%; 95% CI: 0%-3.6%) with CSF cultures had bacterial meningitis; 2 of 645 (0.3%; 95% CI: 0.1%-1.1%) infants with 30-day follow-up had adverse events, including lymphadenitis (1) and culture-negative sepsis (1). Diagnostic testing for IBI varied across sites and by age; overall, 278 (17.0%) had blood cultures, and 102 (6.2%) had CSF cultures obtained. Compared with infants 0 to 28 days old, older infants were less likely to have blood cultures (P < .001) or CSF cultures (P < .001) obtained.CONCLUSION: Afebrile infants with clinician-diagnosed AOM have a low prevalence of IBIs and adverse events; therefore, outpatient management without diagnostic testing may be reasonable.

  View details for DOI 10.1542/peds.2020-1571

  View details for PubMedID 33288730

• Using In Situ Simulations to Improve Pediatric Patient Safety in Emergency Departments. Academic medicine : journal of the Association of American Medical Colleges Lee, M. O., Schertzer, K., Khanna, K., Wang, N. E., Camargo, C. A., Sebok-Syer, S. S. 2020

  Abstract

  PROBLEM: Given the complex interaction between patients, individual providers, health care teams, and the clinical environment, patient safety events with serious consequences are most likely to occur in intensive care units, operating rooms, and emergency departments (EDs). With low-frequency, high-risk events such as pediatric resuscitations, health care teams working in EDs may not have the clinical opportunity to identify deficiencies, review and reinforce knowledge and skills, and problem solve in authentic clinical conditions. Without creating opportunities to safely practice, hospitals run the risk of having health care teams and environments that are not prepared to provide optimal patient care.APPROACH: Researchers employed a case series design and used a train-the-trainer model for in situ simulation. They trained health care professionals (instructors) in 3 general, non-academic EDs in the San Francisco Bay area of California to perform pediatric resuscitation in situ simulations in 2018-2019. In situ simulations occur in the clinical work environment with simulation participants (teams) who are health care professionals taking care of actual patients.OUTCOMES: Teams made up of physicians, nurses, and ED technicians were evaluated for clinical performance, teamwork, and communication during in situ simulations conducted by instructors at baseline, 6 months, and 12 months. Debriefing after the simulations identified multiple latent safety threats (i.e., unidentified potential safety hazards) that were previously unknown. Each ED's pediatric readiness-their ability to provide emergency care for children-was evaluated at baseline and 12 months.NEXT STEPS: The authors will continue to monitor and examine the impact and sustainability of the pediatric in situ simulation program on pediatric readiness scores and its possible translation to other high-risk clinical settings, as well as explore the relationship between in situ simulations and patient outcomes.

  View details for DOI 10.1097/ACM.0000000000003807

  View details for PubMedID 33116057

• Gender balance at oncology conferences in China LANCET ONCOLOGY Biskup, E., Xin, Z., Khanna, K., Leung, T., Zhang, H. 2020; 21 (9): 1138–40

  View details for Web of Science ID 000568490900029

• Gender balance at oncology conferences in China. The Lancet. Oncology Biskup, E., Xin, Z., Khanna, K., Leung, T. I., Zhang, H. 2020; 21 (9): 1138–40

  View details for DOI 10.1016/S1470-2045(20)30463-0

  View details for PubMedID 32888449

• Acute severe paediatric asthma: study protocol for the development of a core outcome set, a Pediatric Emergency Reserarch Networks (PERN) study. Trials Craig, S., Babl, F. E., Dalziel, S. R., Gray, C., Powell, C., Al Ansari, K., Lyttle, M. D., Roland, D., Benito, J., Velasco, R., Hoeffe, J., Moldovan, D., Thompson, G., Schuh, S., Zorc, J. J., Kwok, M., Mahajan, P., Johnson, M. D., Sapien, R., Khanna, K., Rino, P., Prego, J., Yock, A., Fernandes, R. M., Santhanam, I., Cheema, B., Ong, G., Chong, S., Graudins, A., Pediatric Emergency Research Networks (PERN), Kupperman, N., Dalziel, S., Babl, F., Chamberlain, J., Johnson, D., Lyttle, M., Mintegi, S., Mistry, R., Nigrovic, L., Plint, A., Roland, D., Van de Van de Voorde, P. 2020; 21 (1): 72

  Abstract

  BACKGROUND: Acute severe childhood asthma is an infrequent, but potentially life-threatening emergency condition. There is a wide range of different approaches to this condition, with very little supporting evidence, leading to significant variation in practice. To improve knowledge in this area, there must first be consensus on how to conduct clinical trials, so that valid comparisons can be made between future studies. We have formed an international working group comprising paediatricians and emergency physicians from North America, Europe, Asia, the Middle East, Africa, South America, Central America, Australasia and the United Kingdom.METHODS/DESIGN: A 5-stage approach will be used: (1) a comprehensive list of outcomes relevant to stakeholders will be compiled through systematic reviews and qualitative interviews with patients, families, and clinicians; (2) Delphi methodology will be applied to reduce the comprehensive list to a core outcome set; (3) we will review current clinical practice guidelines, existing clinical trials, and literature on bedside assessment of asthma severity. We will then identify practice differences in tne clinical assessment of asthma severity, and determine whether further prospective work is needed to achieve agreement on inclusion criteria for clinical trials in acute paediatric asthma in the emergency department (ED) setting; (4) a retrospective chart review in Australia and New Zealand will identify the incidence of serious clinical complications such as intubation, ICU admission, and death in children hospitalized with acute severe asthma. Understanding the incidence of such outcomes will allow us to understand how common (and therefore how feasible) particular outcomes are in asthma in the ED setting; and finally (5) a meeting of the Pediatric Emergency Research Networks (PERN) asthma working group will be held, with invitation of other clinicians interested in acute asthma research, and patients/families. The group will be asked to achieve consensus on a core set of outcomes and to make recommendations for the conduct of clinical trials in acute severe asthma. If this is not possible, the group will agree on a series of prioritized steps to achieve this aim.DISCUSSION: The development of an international consensus on core outcomes is an important first step towards the development of consensus guidelines and standardised protocols for randomized controlled trials (RCTs) in this population. This will enable us to better interpret and compare future studies, reduce risks of study heterogeneity and outcome reporting bias, and improve the evidence base for the management of this important condition.

  View details for DOI 10.1186/s13063-019-3785-6

  View details for PubMedID 31931862

• Emergency department implementation of abbreviated magnetic resonance imaging for pediatric traumatic brain injury. Journal of the American College of Emergency Physicians open Lumba-Brown, A. n., Lee, M. O., Brown, I. n., Cornwell, J. n., Dannenberg, B. n., Fang, A. n., Ghazi-Askar, M. n., Grant, G. n., Imler, D. n., Khanna, K. n., Lowe, J. n., Wang, E. n., Wintermark, M. n. 2020; 1 (5): 994–99

  Abstract

  Pediatric head injury is a common presenting complaint in the emergency department (ED), often requiring neuroimaging or ED observation for diagnosis. However, the traditional diagnostic neuroimaging modality, head computed tomography (CT), is associated with radiation exposure while prolonged ED observation impacts patient flow and resource utilization. Recent scientific literature supports abbreviated, or focused and shorter, brain magnetic resonance imaging (MRI) as a feasible and accurate diagnostic alternative to CT for traumatic brain injury. However, this is a relatively new application and its use is not widespread. The aims of this review are to describe the science and applications of abbreviated brain MRI and report a model protocol's development and ED implementation in the evaluation of children with head injury for replication in other institutions.

  View details for DOI 10.1002/emp2.12055

  View details for PubMedID 33145550

  View details for PubMedCentralID PMC7593499

• 2018 Academic Emergency Medicine Consensus Conference: A Workforce Development Research Agenda for Pediatric Care in the Emergency Department Merritt, C., Dietrich, A. M., Bogie, A. L., Wu, F., Khanna, K., Ballasiotes, M., Gerardi, M., Ishimine, P. T., Denninghoff, K. R., Saidinejad, M. WILEY. 2019: 1063–73

  View details for DOI 10.1111/acem.13638

  View details for Web of Science ID 000484991400010

• 2018 Academic Emergency Medicine Consensus Conference: A Workforce Development Research Agenda for Pediatric Care in the Emergency Department. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Merritt, C., Dietrich, A. M., Bogie, A. L., Wu, F., Khanna, K., Ballasiotes, M. K., Gerardi, M., Ishimine, P. T., Denninghoff, K. R., Saidinejad, M. 2018

  Abstract

  Each year, more than 30 million children visit US emergency departments (EDs). Though the number of pediatric emergency medicine specialists continues to rise, the vast majority of children are cared for in general EDs outside of children's hospitals. The diverse workforce of care providers for children must possess the knowledge, experience, skills and systemic support necessary to deliver excellent pediatric emergency care. There is a crucial need to understand the factors that drive the professional development and support systems of this diverse workforce. Through the iterative process culminating with the 2018 Academic Emergency Medicine consensus conference, we have identified 5 key research themes and prioritized a specific research agenda. These themes represent critical gaps in our understanding of the development and maintenance of the pediatric emergency care workforce and allow for a prioritization of future research efforts. Only by more fully understanding the gaps in workforce needs, and the necessary steps to address these gaps, can outcomes be optimized for children in need of emergency care. This article is protected by copyright. All rights reserved.

  View details for PubMedID 30338608

• Identifying the Components of a Core Health Services Package from a Human Rights Perspective to Inform Progress Toward Universal Health Coverage HUMAN RIGHTS QUARTERLY Chapman, A. R., Forman, L., Lamprea, E., Khanna, K. 2018; 40 (2): 342–68

  View details for DOI 10.1353/hrq.2018.0018

  View details for Web of Science ID 000432961300006

• Acute Rheumatic Fever: An Evidence-Based Approach To Diagnosis And Initial Management. Pediatric emergency medicine practice Khanna, K., Liu, D. R. 2016; 13 (8): 1-23

  Abstract

  Acute rheumatic fever is an inflammatory reaction involving the joints, heart, and nervous system that occurs after a group A streptococcal infection. It typically presents as a febrile illness with clinical manifestations that could include arthritis, carditis, skin lesions, or abnormal movements. Of these, the cardiac manifestations of acute rheumatic fever are most concerning, as children may present in acute heart failure and may go on to develop valvular insufficiency or stenosis. Because this is a rare presentation to emergency departments in developed countries, it is crucial for clinicians to keep a broad differential when presented with clinical presentations suspicious for acute rheumatic fever. This issue focuses on the clinical evaluation and treatment of patients with acute rheumatic fever by offering a thorough review of the literature on diagnosis and recommendations on appropriate treatment.

  View details for PubMedID 27462838

• The Greater Good: How Supervising Physicians Make Entrustment Decisions in the Pediatric Emergency Department ACADEMIC PEDIATRICS Tiyyagura, G., Balmer, D., Chaudoin, L., Kessler, D., Khanna, K., Srivastava, G., Chang, T. P., Auerbach, M. 2014; 14 (6): 597-602

  View details for Web of Science ID 000344966800012

• Global Health and Emergency Care: A Postgraduate Medical Education Consensus-based Research Agenda ACADEMIC EMERGENCY MEDICINE Martin, I. B., Jacquet, G. A., Levine, A. C., Douglass, K., Pousson, A., Dunlop, S., Khanna, K., Bentley, S., Tupesis, J. P. 2013; 20 (12): 1233-1240

  Abstract

  Global emergency medicine (EM) is a rapidly growing field within EM, as evidenced by the increasing number of trainees and clinicians pursuing additional experiences in global health and emergency care. In particular, many trainees now desire opportunities at the postgraduate level by way of global EM fellowship programs. Despite this growing popularity, little is known of the effects of postgraduate training in global health and emergency care on learners and patients in the United States and abroad. During the 2013 Academic Emergency Medicine consensus conference on global health and emergency care, a group of leading educators at the postgraduate medical education level convened to generate a research agenda of pressing questions to be answered in this area. The consensus-based research agenda is presented in this article.

  View details for DOI 10.1111/acem.12258

  View details for Web of Science ID 000328566800004

  View details for PubMedID 24341578

• The Role of Graduate Medical Education in Global Health: Proceedings From the 2013 Academic Emergency Medicine Consensus Conference ACADEMIC EMERGENCY MEDICINE Tupesis, J. P., Jacquet, G. A., Hilbert, S., Pousson, A., Khanna, K., Ross, J., Butteris, S., Martin, I. B. 2013; 20 (12): 1216-1223

  Abstract

  The past 40 years have seen expanded development of emergency medicine (EM) postgraduate residency training programs worldwide. An important part of this educational experience is the ability of resident trainees to participate in experiences abroad. However, little is known about how these experiences shape trainees and the populations they serve. During the 2013 Academic Emergency Medicine consensus conference, a group of educators met to define and outline current trends in graduate medical education (GME) emergency care research. The authors discuss future research questions bridging the gap of GME and global health.

  View details for DOI 10.1111/acem.12260

  View details for Web of Science ID 000328566800002

  View details for PubMedID 24341576

• Qualitative Evaluation of Just-in-Time Simulation-Based Learning The Learners' Perspective SIMULATION IN HEALTHCARE-JOURNAL OF THE SOCIETY FOR SIMULATION IN HEALTHCARE Kamdar, G., Kessler, D. O., Tilt, L., Srivastava, G., Khanna, K., Chang, T. P., Balmer, D., Auerbach, M. 2013; 8 (1): 43-48

  Abstract

  Just-in-time training (JITT) is an educational strategy where training occurs in close temporal proximity to a clinical encounter. A multicenter study evaluated the impact of simulation-based JITT on interns' infant lumbar puncture (LP) success rates. Concurrent with this multicenter study, we conducted a qualitative evaluation to describe learner perceptions of this modality of skills training.Eleven interns from a single institution participated in a face-to-face semistructured interview exploring their JITT experience. Interviews were audio-recorded and transcribed. Two investigators reviewed the transcripts, assigned codes to the data, and categorized the codes. Categories were modified by 4 emergency physicians. As a means of data triangulation, we performed focus groups at a second institution.Benefits of JITT included review of anatomic landmarks, procedural rehearsal, and an opportunity to ask questions. These perceived benefits improved confidence with infant LP. Deficits of the training included lack of mannequin fidelity and unrealistic context when compared with an actual LP. An unexpected category, which emerged from our analysis, was that of barriers to JITT performance. Barriers included lack of time in a busy clinical setting and various instructor factors. The focus group findings confirmed and elaborated the benefits and deficits of JITT and the barriers to JITT performance.Just-in-time training improved procedural confidence with infant LP, but work place busyness and instructor lack of support or unawareness were barriers to JITT performance. Optimal LP JITT would occur with improved contextual fidelity. More research is needed to determine optimal training strategies that are effective for the learner and maximize clinical outcomes for the patient.

  View details for DOI 10.1097/SIH.0b013e31827861e8

  View details for Web of Science ID 000314807500008

  View details for PubMedID 23299050

• Epididymo-Orchitis Fleisher and Ludwig's 5-Minute Pediatric Emergency Medicine Consult Khanna, K., Liu, D. . Wolters Kluwer, Lippincott, Williams and Wilkings. 2011
• Emergency Department Surge: Models and Practical Implications National Summit on Pediatric Disaster and Emergency Services Nager, A. L., Khanna, K. LIPPINCOTT WILLIAMS & WILKINS. 2009: S96–S99

  Abstract

  Emergency Department crowding has long been described. Despite the daily challenges of managing emergency department volume and acuity; a surge response during a disaster entails even greater challenges including collaboration, intervention, and resourcefulness to effectively carry out pediatric disaster management. Understanding surge and how to respond with appropriate planning will lead to success. To achieve this, we sought to analyze models of surge; review regional and national data outlining surge challenges and factors that impact surge; and to outline potential solutions.We conducted a systemic review and included articles and documents that best described the theoretical and practical basis of surge response. We organized the systematic review according to the following questions: What are the elements and models that are delineated by the concept of surge? What is the basis for surge response based on regional and national published sources? What are the broad global solutions? What are the major lessons observed that will impact effective surge capacity?Multiple models of surge are described including public health, facility-based and community-based; a 6-tiered response system; and intrinsic or extrinsic surge capacity. In addition, essential components (4 S's of surge response) are described along with regional and national data outlining surge challenges, impacting factors, global solutions, and lesions observed.There are numerous shortcomings regionally and nationally affecting our ability to provide an effective and coordinated surge response. Planning, education, and training will lead to an effective pediatric disaster management response.

  View details for DOI 10.1097/TA.0b013e3181ad2aaa

  View details for Web of Science ID 000268898600009

  View details for PubMedID 19667863