All Publications

  • Deep Learning-Based Reconstruction for Cardiac MRI: A Review. Bioengineering (Basel, Switzerland) Oscanoa, J. A., Middione, M. J., Alkan, C., Yurt, M., Loecher, M., Vasanawala, S. S., Ennis, D. B. 2023; 10 (3)


    Cardiac magnetic resonance (CMR) is an essential clinical tool for the assessment of cardiovascular disease. Deep learning (DL) has recently revolutionized the field through image reconstruction techniques that allow unprecedented data undersampling rates. These fast acquisitions have the potential to considerably impact the diagnosis and treatment of cardiovascular disease. Herein, we provide a comprehensive review of DL-based reconstruction methods for CMR. We place special emphasis on state-of-the-art unrolled networks, which are heavily based on a conventional image reconstruction framework. We review the main DL-based methods and connect them to the relevant conventional reconstruction theory. Next, we review several methods developed to tackle specific challenges that arise from the characteristics of CMR data. Then, we focus on DL-based methods developed for specific CMR applications, including flow imaging, late gadolinium enhancement, and quantitative tissue characterization. Finally, we discuss the pitfalls and future outlook of DL-based reconstructions in CMR, focusing on the robustness, interpretability, clinical deployment, and potential for new methods.

    View details for DOI 10.3390/bioengineering10030334

    View details for PubMedID 36978725

  • Semi-Supervised Learning of MRI Synthesis Without Fully-Sampled Ground Truths IEEE TRANSACTIONS ON MEDICAL IMAGING Yurt, M., Dalmaz, O., Dar, S., Ozbey, M., Tinaz, B., Oguz, K., Cukur, T. 2022; 41 (12): 3895-3906


    Learning-based translation between MRI contrasts involves supervised deep models trained using high-quality source- and target-contrast images derived from fully-sampled acquisitions, which might be difficult to collect under limitations on scan costs or time. To facilitate curation of training sets, here we introduce the first semi-supervised model for MRI contrast translation (ssGAN) that can be trained directly using undersampled k-space data. To enable semi-supervised learning on undersampled data, ssGAN introduces novel multi-coil losses in image, k-space, and adversarial domains. The multi-coil losses are selectively enforced on acquired k-space samples unlike traditional losses in single-coil synthesis models. Comprehensive experiments on retrospectively undersampled multi-contrast brain MRI datasets are provided. Our results demonstrate that ssGAN yields on par performance to a supervised model, while outperforming single-coil models trained on coil-combined magnitude images. It also outperforms cascaded reconstruction-synthesis models where a supervised synthesis model is trained following self-supervised reconstruction of undersampled data. Thus, ssGAN holds great promise to improve the feasibility of learning-based multi-contrast MRI synthesis.

    View details for DOI 10.1109/TMI.2022.3199155

    View details for Web of Science ID 000907324600035

    View details for PubMedID 35969576