Natali Murad Barakat
MD Student with Scholarly Concentration in Biomedical Ethics & Medical Humanities, expected graduation Spring 2028
All Publications
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Sustaining cardiac surgery in low-resource settings: Financial and training lessons from Tenwek Hospital, Kenya.
JTCVS open
2026; 31: 101734
Abstract
To examine how a mission-based teaching hospital in rural Kenya has evolved into a high-volume regional training hub, evaluate its financing and cost-control mechanisms, and derive lessons for scaling advanced care in sub-Saharan Africa.Institutional financial records, clinical volumes, and stakeholder interviews (2008-2025) were reviewed across 3 domains: (1) funding streams, (2) cost-containment mechanisms, and (3) long-term sustainability strategies. Themes were analyzed descriptively for relevance to other low-resource settings.Tenwek, a 400-bed mission referral hospital serving more than a million residents in Southwest Kenya, inaugurated a new cardiothoracic center in 2024 with capacity for 2000 cases per year-one of the largest in sub-Saharan Africa. This expansion is expected to multiply Kenya's national cardiac surgery volume several-fold, substantially reducing delays in care. Since the program began, the hospital has performed more than 1500 operations, of which 436 (27.7%) were for congenital diseases. Perioperative 30-day mortality was 4.4%, whereas overall all-cause mortality during the study period was 9.6%. The program relies on a mixed funding model-public health insurance, philanthropic funds (eg, Compassionate Cardiac Fund), mission partnerships, and community sponsorships-that collectively support supplies, equipment, and training. Locally, Tenwek's social work department manages patient sponsorships through church networks, charitable foundations, and individual donors to ensure fair access for patients who are indigent. Sustainability has been enhanced through employing more than 300 local staff, bulk-purchasing agreements, and safe reuse protocols. The program's fellowship is gradually localizing expertise by graduating some of the first cardiothoracic surgeons from multiple African countries, equipped with the infrastructure to support their future practice in their respective nations. This effectively shapes the continent's future workforce and reduces dependence on external expertise.Tenwek's experience demonstrates that sustained cardiac surgery in low-resource settings is achievable through (1) diversified funding, (2) cost control with gradual workforce localization, and (3) social equity mechanisms protecting patients from catastrophic expenditure. These principles offer a pragmatic framework for developing self-sustaining cardiac surgical programs across the Global South.
View details for DOI 10.1016/j.xjon.2026.101734
View details for PubMedID 42381959
View details for PubMedCentralID PMC13316347
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Sustaining Cardiac Surgery in Low-Resource Settings: Financial and Training Lessons from Tenwek Hospital, Kenya
MOSBY-ELSEVIER. 2026: S74-S75
View details for DOI 10.1016/j.jtcvs.2026.03.176
View details for Web of Science ID 001765327200009
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A MUC1-overexpressing epithelial population is associated with CDH1 loss-of-function gastric adenocarcinoma.
AMER ASSOC CANCER RESEARCH. 2026
View details for DOI 10.1158/1538-7445.AM2026-2270
View details for Web of Science ID 001734175500036