Hypophosphite addition to alkenes under solvent-free and non-acidic aqueous conditions.
Chemical communications (Cambridge, England)
Hypophosphite adds to alkenes in high yields under solvent-free conditions at elevated temperature, including alpha,beta-unsaturated carboxylates. The reaction proceeds by a radical mediated pathway. Hypophosphite addition is also effective under non-acidic aqueous conditions employing radical initiators. These methods complement other hypophosphite addition reactions and simplify the synthesis of polyfunctional H-phosphinates.
View details for DOI 10.1039/d1cc06831h
View details for PubMedID 35060983