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  • Hypophosphite addition to alkenes under solvent-free and non-acidic aqueous conditions. Chemical communications (Cambridge, England) Huang, Z., Chen, Y., Kanan, M. W. 1800


    Hypophosphite adds to alkenes in high yields under solvent-free conditions at elevated temperature, including alpha,beta-unsaturated carboxylates. The reaction proceeds by a radical mediated pathway. Hypophosphite addition is also effective under non-acidic aqueous conditions employing radical initiators. These methods complement other hypophosphite addition reactions and simplify the synthesis of polyfunctional H-phosphinates.

    View details for DOI 10.1039/d1cc06831h

    View details for PubMedID 35060983