Independent Labs, Institutes, and Centers (Dean of Research)
Showing 121-130 of 171 Results
-
John Mitchell
Mary and Gordon Crary Family Professor in the School of Engineering, and Professor, by courtesy, of Electrical Engineering and of Education
Current Research and Scholarly InterestsProgramming languages, computer security and privacy, blockchain, machine learning, and technology for education
-
Anish Mitra
Assistant Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology)
BioAnish Mitra is a neuroscientist and psychiatrist interested in understanding how neural activity in large-scale networks causes mental illness.
-
Daria Mochly-Rosen
George D. Smith Professor of Translational Medicine
Current Research and Scholarly InterestsTwo areas: 1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling. Focus: protein kinase C in heart and large GTPases regulating mitochondrial dynamics in neurodegdenration. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, and glucose-6-phoshate dehydrogenase, in normal cells and in models of human diseases.
-
W. E. Moerner
Harry S. Mosher Professor and Professor, by courtesy, of Applied Physics
Current Research and Scholarly InterestsLaser spectroscopy and microscopy of single molecules to probe biological systems, one biomolecule at a time. Primary thrusts: fluorescence microscopy far beyond the optical diffraction limit (PALM/STORM/STED), methods for 3D optical microscopy in cells, and trapping of single biomolecules in solution for extended study. We explore protein localization patterns in bacteria, structures of amyloid aggregates in cells, signaling proteins in the primary cilium, and dynamics of DNA and RNA.
-
Matteo Amitaba Mole'
Assistant Professor of Obstetrics and Gynecology (Reproductive & Stem Cell Biology)
Current Research and Scholarly InterestsThe research focus of our laboratory is centered on investigating the complex process of human embryo implantation. Due to the limited availability of suitable model systems and inability to directly observe this process in vivo, this has been traditionally referred to as the enigmatic stage of human embryonic development.
The successful implantation of an embryo is crucial for the establishment of a healthy pregnancy. During the transition between the first and second week of gestation, the human embryo must securely implant into the maternal uterus, initiating development of the placenta to receive necessary nutrients and oxygen for its growth until birth.
However, the process of implantation in humans is highly susceptible to failure, with a significant percentage of embryos unable to develop beyond this stage leading to early miscarriages. This clinically observed "implantation barrier" often requires patients to undergo numerous cycles of IVF treatment, with no guarantee of a successful pregnancy outcome.
The primary objective is to increase the understanding of maternal-embryo interactions initiated at implantation, with the goal of developing clinical interventions to address the high incidence of implantation failures underlying pre-clinical miscarriages.