Wu Tsai Human Performance Alliance
Showing 41-60 of 213 Results
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David N. Cornfield
Anne T. and Robert M. Bass Professor of Pediatric Pulmonary Medicine and Professor, by courtesy, of Surgery
Current Research and Scholarly InterestsOver the past 20 years, the Cornfield Laboratory has focused upon basic, translational and clinical research, with a primary focus on lung biology. As an active clinician-scientist, delivering care to acutely and chronically ill infants and children, our lab focuses on significant clinical challenges and tried to use science to craft novel solutions to difficult clinical problems.
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Alia Crum
Associate Professor of Psychology and, by courtesy, of Medicine (Primary Care & Population Health)
Current Research and Scholarly InterestsOur lab focuses on how subjective mindsets (e.g., thoughts, beliefs and expectations) can alter objective reality through behavioral, psychological, and physiological mechanisms. We are interested in understanding how mindsets affect important outcomes both within and beyond the realm of medicine, in the domains such as exercise, diet and stress. https://mbl.stanford.edu/
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Francesco Nandkumar Dandekar
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Dandekar is the Associate Director of Sports Psychiatry and a Clinical Assistant Professor at Stanford University. After graduating summa cum laude from the University of Southern California with a B.S. in Biomedical Engineering, he earned a Regents Scholarship to complete his M.D. at UC San Diego, where he received the American Academy of Neurology’s Prize for Excellence. During his residency and fellowship at Stanford, Dr. Dandekar provided care to a variety of patients utilizing a combination of medication management, psychotherapy, and lifestyle changes (sleep, nutrition, exercise, recovery). Teamed with Clinical Professor Dr. Douglas Noordsy, he helped to incorporate psychiatric services into Stanford's sports psychology program, and continues to see elite athletes as part of the Stanford Sports Psychiatry Clinic. He also specializes in treating physicians, and sees many residents, fellows, and attendings in his private practice. In his free time, he enjoys playing tennis, chess, and guitar.
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Bruce Daniel
Professor of Radiology (Body Imaging) and, by courtesy, of Bioengineering
Current Research and Scholarly Interests1. MRI of Breast Cancer, particularly new techniques. Currently being explored are techniques including ultra high spatial resolution MRI and contrast-agent-free detection of breast tumors.
2. MRI-guided interventions, especially MRI-compatible remote manipulation and haptics
3. Medical Mixed Reality. Currently being explored are methods of fusing patients and their images to potentially improve breast conserving surgery, and other conditions. -
Reinhold Dauskardt
Ruth G. and William K. Bowes Professor in the School of Engineering
BioDauskardt and his group have worked extensively on integrating new materials into emerging technologies including thin-film structures for nanoscience and energy technologies, high-performance composite and laminates for aerospace, and on biomaterials and soft tissues in bioengineering. His group has pioneered methods for characterizing adhesion and cohesion of thin films used extensively in device technologies. His research on wound healing has concentrated on establishing a biomechanics framework to quantify the mechanical stresses and biologic responses in healing wounds and define how the mechanical environment affects scar formation. Experimental studies are complimented with a range of multiscale computational capabilities. His research includes interaction with researchers nationally and internationally in academia, industry, and clinical practice.
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John W. Day, MD, PhD
Professor of Neurology, of Pediatrics (Genetics) and, by courtesy, of Pathology
On Partial Leave from 05/15/2023 To 06/15/2023Current Research and Scholarly InterestsOur Neuromuscular Division coordinates a comprehensive effort to conquer peripheral nerve and muscle disorders, including the muscular dystrophies, motor neuron disorders, neuromuscular junction abnormalities, and peripheral neuropathies. With patients and families foremost in mind, we have had success defining and combating these diseases, with research focused on identifying genetic causes, developing novel treatment, and maximizing patient function by optimizing current management.
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Luis de Lecea
Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical and Translational Neurosciences Incubator)
Current Research and Scholarly InterestsMy lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction.
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Scott L. Delp, Ph.D.
Director, Wu Tsai Human Performance Alliance at Stanford, James H. Clark Professor in the School of Engineering, Professor of Bioengineering, of Mechanical Engineering and, by courtesy, of Orthopaedic Surgery
Current Research and Scholarly InterestsExperimental and computational approaches to study human movement. Development of biomechanical models to analyze muscle function, study movement abnormalities, design medical products, and guide surgery. Imaging and health technology development. Discovering the principles of peak performance to advance human health. Human performance research. Wearable technologies, video motion capture, and machine learning to enable large-scale analysis.
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Joseph M. DeSimone
Sanjiv Sam Gambhir Professor of Translational Medicine, Professor of Chemical Engineering and, by courtesy, of Chemistry, of Materials Science and Engineering, and of Operations, Information and Technology at the Graduate School of Business
BioJoseph M. DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine and Chemical Engineering at Stanford University. He holds appointments in the Departments of Radiology and Chemical Engineering with courtesy appointments in the Department of Chemistry and in Stanford’s Graduate School of Business.
The DeSimone laboratory's research efforts are focused on developing innovative, interdisciplinary solutions to complex problems centered around advanced polymer 3D fabrication methods. In Chemical Engineering and Materials Science, the lab is pursuing new capabilities in digital 3D printing, as well as the synthesis of new polymers for use in advanced additive technologies. In Translational Medicine, research is focused on exploiting 3D digital fabrication tools to engineer new vaccine platforms, enhanced drug delivery approaches, and improved medical devices for numerous conditions, with a current major focus in pediatrics. Complementing these research areas, the DeSimone group has a third focus in Entrepreneurship, Digital Transformation, and Manufacturing.
Before joining Stanford in 2020, DeSimone was a professor of chemistry at the University of North Carolina at Chapel Hill and of chemical engineering at North Carolina State University. He is also Co-founder, Board Chair, and former CEO (2014 - 2019) of the additive manufacturing company, Carbon. DeSimone is responsible for numerous breakthroughs in his career in areas including green chemistry, medical devices, nanomedicine, and 3D printing. He has published over 350 scientific articles and is a named inventor on over 200 issued patents. Additionally, he has mentored 80 students through Ph.D. completion in his career, half of whom are women and members of underrepresented groups in STEM.
In 2016 DeSimone was recognized by President Barack Obama with the National Medal of Technology and Innovation, the highest U.S. honor for achievement and leadership in advancing technological progress. He has received numerous other major awards in his career, including the U.S. Presidential Green Chemistry Challenge Award (1997); the American Chemical Society Award for Creative Invention (2005); the Lemelson-MIT Prize (2008); the NIH Director’s Pioneer Award (2009); the AAAS Mentor Award (2010); the Heinz Award for Technology, the Economy and Employment (2017); the Wilhelm Exner Medal (2019); the EY Entrepreneur of the Year Award (2019 U.S. Overall National Winner); and the Harvey Prize in Science and Technology (2020). He is one of only 25 individuals elected to all three branches of the U.S. National Academies (Sciences, Medicine, Engineering). DeSimone received his B.S. in Chemistry in 1986 from Ursinus College and his Ph.D. in Chemistry in 1990 from Virginia Tech. -
Joseph P. Donahue
Clinical Associate Professor, Orthopaedic Surgery
BioDr. Donahue is a Board Certified Orthopaedic Surgeon with Subspecialty Certification in Orthopaedic Sports Medicine. He is fellowship trained and specializes in Arthroscopic and Minimally Invasive Reconstructive Surgery of the Shoulder and Knee, and Sports Medicine.
Dr. Donahue received his undergraduate degree from Stanford University and his Doctor of Medicine from Columbia University College of Physicians and Surgeons. He completed his residency in Orthopedic Surgery at St. Luke’s-Roosevelt Hospital Center (NYC), Memorial Sloan-Kettering Cancer Center (NYC), and the Alfred I. duPont Institute (DE), and went on to a fellowship in Orthopedic Sports Medicine at the Stanford/SOAR Sports Medicine Fellowship Program.
Dr. Donahue’s interests include arthroscopic surgery of the shoulder and knee. He specializes in anterior cruciate ligament injuries, shoulder instability, and rotator cuff tears. He has done research on both shoulder instability and rotator cuff tears and has developed new techniques and medical devices for rotator cuff and all soft tissue repairs. He has started and actively serves on the medical advisory board for several surgical device companies and continues to design new surgical devices for arthroscopic procedures. He has authored several device patents and journal articles.
Dr. Donahue has been a member of the American Academy of Orthopedic Surgeons and a Diplomat of the American Board of Orthopedic Surgery. He is also member of the Arthroscopy Association of North America, the American Orthopedic Society of Sports Medicine, the California Orthopedic Association, The International Knee Society, the California Medical Association, and the Santa Clara Medical Society.
Dr. Donahue has served as the Program Director of the SOAR Orthopedic Sports Medicine Fellowship Program. He has served as the Director of Santa Clara University’s Sports Medicine Program and the Head Team Physician for all of Santa Clara University’s athletic teams, a team physician for the San Francisco 49ers, the San Francisco Giants, the Stanford Athletic Department, and many other area collegiate and high school teams. -
Alfredo Dubra, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsOur lab seeks to help the early diagnosing and monitoring progression of ocular, vascular, neurodegenerative and systemic diseases through novel non-invasive optical ophthalmic imaging. We pursue this goal through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines.
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Johannes C. Eichstaedt
Assistant Professor (Research) of Psychology
Current Research and Scholarly InterestsI use large-scale language analyses and machine learning to characterize disease risk, measure subjective well-being and mental health of populations, and enrich and test psychological theory. I focus on applications of these methods that inform public health and public policy, and to create health systems that are more responsive to mental illness.
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Antoine Falisse
Postdoctoral Scholar, Bioengineering
BioDr. Falisse is a postdoctoral fellow in Bioengineering working on computational approaches to study human movement disorders. He primarily uses optimization methods, biomechanical modeling, and data from various sources (wearables, videos, medical images) to get insights into movement abnormalities and design innovative treatments and rehabilitation protocols.
Dr. Falisse received his PhD from KU Leuven (Belgium) where he worked on modeling and simulating the locomotion of children with cerebral palsy. His research was supported by the Research Foundation Flanders (FWO) through a personal fellowship. Dr. Falisse received several awards for his PhD work, including the David Winter Young Investigator Award, the Andrzej J. Komor Young Investigator Award, the VPHi Thesis Award in In Silico Medicine, and the KU Leuven Research Council Award in Biomedical Sciences. -
Chelsea Finn
Assistant Professor of Computer Science and of Electrical Engineering
BioChelsea Finn is an Assistant Professor in Computer Science and Electrical Engineering at Stanford University, and the William George and Ida Mary Hoover Faculty Fellow. Professor Finn's research interests lie in the ability to enable robots and other agents to develop broadly intelligent behavior through learning and interaction. Her work lies at the intersection of machine learning and robotic control, including topics such as end-to-end learning of visual perception and robotic manipulation skills, deep reinforcement learning of general skills from autonomously collected experience, and meta-learning algorithms that can enable fast learning of new concepts and behaviors. Professor Finn received her Bachelors degree in Electrical Engineering and Computer Science at MIT and her PhD in Computer Science at UC Berkeley. Her research has been recognized through the ACM doctoral dissertation award, an NSF graduate fellowship, a Facebook fellowship, the C.V. Ramamoorthy Distinguished Research Award, and the MIT Technology Review 35 under 35 Award, and her work has been covered by various media outlets, including the New York Times, Wired, and Bloomberg. Throughout her career, she has sought to increase the representation of underrepresented minorities within CS and AI by developing an AI outreach camp at Berkeley for underprivileged high school students, a mentoring program for underrepresented undergraduates across three universities, and leading efforts within the WiML and Berkeley WiCSE communities of women researchers.
Website: https://ai.stanford.edu/~cbfinn -
Michael Fischbach
Associate Professor of Bioengineering and of Medicine (Microbiology and Immunology)
Current Research and Scholarly InterestsThe human microbiome is linked to a range of phenotypes in the host, but it remains difficult to test causality and explore the mechanisms of these interactions. Our lab focuses on two research areas that share a common goal of studying host-microbiota interactions at the level of molecular mechanism:
1) Technology development. Much of what we know about biology has been learned by deleting individual genes from mice, worms, flies and yeast. The ability to do single-strain and single-gene deletion in the microbiome would be transformative but does not yet exist. We are developing technology in three areas to make this possible:
Synthetic ecology: There is a pressing need for model systems for the microbiome that are defined, but of an order of complexity that approaches the native state. Key experiments in the field often show that a host phenotype can be transferred to a germ-free mouse via fecal transplant. If these phenomena could be recapitulated with a defined, high-complexity community, then reductionist experiments to probe mechanism would be possible. We are developing the technology required to build highly complex defined communities (100-200 bacterial species), make them stable upon transplantation into mice, and probe their function in vitro and in vivo.
Genetics: It is difficult to probe mechanism without genetics, and genetic tools exist for only ~10% of the bacterial species in the gut and skin microbiome. We are developing technologies that will make it possible to delete and insert genes, and build mutant libraries, in many of the most common bacterial strains in the gut and skin microbiome.
Computation: In previous work from the lab, we have developed computational algorithms that identify small-molecule-producing genes in bacterial genomes. In current work, we are devising algorithms for genome mining that are specific to the microbiome, and new tools for predicting the chemical structures of small molecules from untargeted metabolomics data.
2) Molecular mechanisms. Many of the early findings in microbiome research are correlative or associative. We are applying the tools described above to explore the mechanisms underlying these phenomena:
Small molecules: Our lab has had a long-standing interest in small molecules from the microbiota. These include: 1) host-derived molecules metabolized by the microbiome, like bile acids; 2) characteristic components of the bacterial membrane and cell wall, including LPS and capsular polysaccharides; and 3) hundreds of other diffusible small molecules (e.g., the products of polysaccharide and amino acid metabolism) that are present in the bloodstream at high concentrations. Our work in this area seeks to establish the mechanisms by which these molecules modulate host biology, especially by deleting them one at a time in the background of a complex community; and to discover new microbiome-derived metabolites present in the bloodstream and host tissues.
Ecology of complex communities: Synthetic ecology at the 100+ strain scale is entirely unexplored, and the emergent properties of complex communities are not well understood. Our work in this area seeks to understand basic principles outlined by the following questions: How many meaningful interactions exist in a community of hundreds of strains? What constitutes a niche, molecularly and spatially, and how do strains map to niches? What are the molecular correlates of stability, and how does a community reconfigure in response to a perturbation? How rare or common are stable states, and how predictable is the process by which a consortium will evolve toward a stable state? To what extent do priority effects (early colonists and events) determine the outcome of ecosystem development? Can the results of ecosystem competition be predicted or engineered? -
Michael Fredericson, MD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsMy research focuses on the etiology, prevention, and treatment of overuse sports injuries in athletes and lifestyle medicine practices for improved health and longevity.
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Michael T. Freehill, MD, FAOA
Associate Professor of Orthopaedic Surgery
BioDr. Freehill is a board-certified, double fellowship-trained specialist in orthopaedic surgery with a sub-specialty certification in sports medicine. His concentration is in shoulder and elbow. Dr. Freehill is a team physician for the Stanford University athletics program and head physician for the Stanford University baseball team. Dr. Freehill also teaches in the Department of Orthopaedic Surgery at Stanford University School of Medicine.
Dr. Freehill’s practice focuses on all shoulder conditions. He treats rotator cuff tears, shoulder instability, shoulder arthritis, sports shoulder, arthropathy, complex shoulder pathology, and sports related shoulder injury. In addition, he is also passionate about sports- related elbow injuries, with an emphasis on thrower’s elbow.
Professional and amateur athletes, as well as non-athletes, come to Dr. Freehill for expert care. His sports medicine training and specialization in shoulder replacement procedures enable him to treat patients across the lifespan. Depending on factors including the patient’s condition and occupation, he may recommend treatment ranging from non-operative solutions (such as physical therapy) to cutting-edge biologics procedures or complex surgery.
In addition to his positions within the Stanford University athletics program, Dr. Freehill serves as assistant team physician for the Oakland A’s. Previously, he was a team physician for the Detroit Tigers and the Winston-Salem Dash (affiliated with the Chicago White Sox); he assisted with the Baltimore Orioles. He has also served as Director of Sports Medicine for Wake Forest University Athletics.
As executive director of the Stanford Baseball Science CORE, Dr. Freehill draws on his previous experience as a professional baseball player to help athletes of all skill levels. In the lab, he conducts cutting edge research on the biomechanics of overhead throwers in order to support advances in throwing performance. He has conducted a study on pitch counts in adolescent players funded by Major League Baseball. Dr. Freehill was also awarded a research grant from the National Institutes of Health to investigate stromal vascular fractionated mesenchymal cells and their potential for healing rotator cuff tendon tears.
Dr. Freehill has pioneered the use of some of the latest techniques and technology for leading-edge care. Among the advanced technologies he utilizes is a virtual reality (VR) system that enables him to perform a simulated shoulder arthroplasty procedure prior to entering the operating room with a patient. The system also enables him to predict and order customized implants if needed, which is believed to enable a more positive outcome for patients.
Peer-reviewed articles authored by Dr. Freehill explore rotator cuff injuries, shoulder arthroplasty, baseball-related injuries and performance interests, and more. His work has been featured in the American Journal of Sports Medicine, the Orthopedic Journal of Sports Medicine, Journal of Shoulder and Elbow Surgery, Arthroscopy, and elsewhere. He has written numerous book chapters and made over 200 presentations at conferences around the world.
Dr. Freehill’s honors include an Orthopaedic Residency Research Award while at Johns Hopkins University. He is also a Neer Award winner, denoting the highest research award selected annually by the American Shoulder and Elbow Society.
Currently, he serves on the Medical Publishing Board of Trustees for the American Orthopaedic Society for Sports Medicine. He is a member of the American Orthopaedic Association, and the Major League Baseball Team Physician Association. He is a committee member for the American Shoulder and Elbow Surgeons Society, International Congress of Arthroscopy and Sports Traumatology, the Arthroscopy Association of North America, and the American Academy of Orthopaedic Surgeons. -
Lawrence Fung MD PhD
Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories & Clinical Translational Neurosciences Incubator)
Current Research and Scholarly InterestsDr. Lawrence Fung an assistant professor in the Department of Psychiatry and Behavioral Sciences at Stanford University. He is the director of the Stanford Neurodiversity Project, director of the Neurodiversity Clinic, and principal investigator at the Fung Lab. His work, which focuses on autism and neurodiversity, traverses from multi-modal neuroimaging studies to new conceptualization of neurodiversity and its application to clinical, education, and employment settings. His lab advances the understanding of neural bases of human socio-communicative and cognitive functions by using novel neuroimaging and bioanalytical technologies. Using community-based participatory research approach, his team devises and implements novel interventions to improve the lives of neurodiverse individuals by maximizing their potential and productivity. His work has been supported by various agencies including the National Institutes of Health, Autism Speaks, California Department of Developmental Services, California Department of Rehabilitation, as well as philanthropy. He received his PhD in chemical engineering from Cornell University, and MD from George Washington University. He completed his general psychiatry residency, child and adolescent psychiatry fellowship, and postdoctoral research fellowship at Stanford.
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Ansgar Furst
Clinical Associate Professor (Affiliated), Psych/Public Mental Health & Population Sciences
Staff, Psych/Public Mental Health & Population SciencesBioDr. Furst is a Clinical Associate Professor (affiliated) of Psychiatry and Behavioral Sciences and of Neurology and Neurological Sciences at Stanford University School of Medicine. He is a Principal Investigator and Director of the California War Related Illness and Injury Study Center (WRIISC) Advanced Fellowship Post-Doctoral program and Associate Director of Neuroimaging. He is also a Senior Research Scientist at the Polytrauma System of Care (PSC) at VA Palo Alto Health Care System. Dr. Furst serves as Associate Editor for the journal Frontiers in Neurology and is a member of the editorial board of NEUROLOGY. His research focuses on diagnostics and interventions related to traumatic brain injury, sleep, pain and Alzheimer's disease.
For more information please visit:
https://med.stanford.edu/furstlab.html
