Wu Tsai Neurosciences Institute


Showing 1-35 of 35 Results

  • Jeremy Dahl

    Jeremy Dahl

    Associate Professor of Radiology (Pediatric Radiology)
    On Partial Leave from 07/01/2024 To 06/30/2025

    Current Research and Scholarly InterestsUltrasonic beamforming, imaging methods, systems, and devices.

  • Hongjie Dai

    Hongjie Dai

    The J.G. Jackson and C.J. Wood Professor of Chemistry, Emeritus

    BioProfessor Dai’s research spans chemistry, physics, and materials and biomedical sciences, leading to materials with properties useful in electronics, energy storage and biomedicine. Recent developments include near-infrared-II fluorescence imaging, ultra-sensitive diagnostic assays, a fast-charging aluminum battery and inexpensive electrocatalysts that split water into oxygen and hydrogen fuels.

    Born in 1966 in Shaoyang, China, Hongjie Dai began his formal studies in physics at Tsinghua U. (B.S. 1989) and applied sciences at Columbia U. (M.S. 1991). He obtained his Ph.D. from Harvard U and performed postdoctoral research with Dr. Richard Smalley. He joined the Stanford faculty in 1997, and in 2007 was named Jackson–Wood Professor of Chemistry. Among many awards, he has been recognized with the ACS Pure Chemistry Award, APS McGroddy Prize for New Materials, Julius Springer Prize for Applied Physics and Materials Research Society Mid-Career Award. He has been elected to the American Academy of Arts and Sciences, National Academy of Sciences (NAS), National Academy of Medicine (NAM) and Foreign Member of Chinese Academy of Sciences.

    The Dai Laboratory has advanced the synthesis and basic understanding of carbon nanomaterials and applications in nanoelectronics, nanomedicine, energy storage and electrocatalysis.

    Nanomaterials
    The Dai Lab pioneered some of the now-widespread uses of chemical vapor deposition for carbon nanotube (CNT) growth, including vertically aligned nanotubes and patterned growth of single-walled CNTs on wafer substrates, facilitating fundamental studies of their intrinsic properties. The group developed the synthesis of graphene nanoribbons, and of nanocrystals and nanoparticles on CNTs and graphene with controlled degrees of oxidation, producing a class of strongly coupled hybrid materials with advanced properties for electrochemistry, electrocatalysis and photocatalysis. The lab’s synthesis of a novel plasmonic gold film has enhanced near-infrared fluorescence up to 100-fold, enabling ultra-sensitive assays of disease biomarkers.

    Nanoscale Physics and Electronics
    High quality nanotubes from his group’s synthesis are widely used to investigate the electrical, mechanical, optical, electro-mechanical and thermal properties of quasi-one-dimensional systems. Lab members have studied ballistic electron transport in nanotubes and demonstrated nanotube-based nanosensors, Pd ohmic contacts and ballistic field effect transistors with integrated high-kappa dielectrics.

    Nanomedicine and NIR-II Imaging
    Advancing biological research with CNTs and nano-graphene, group members have developed π–π stacking non-covalent functionalization chemistry, molecular cellular delivery (drugs, proteins and siRNA), in vivo anti-cancer drug delivery and in vivo photothermal ablation of cancer. Using nanotubes as novel contrast agents, lab collaborations have developed in vitro and in vivo Raman, photoacoustic and fluorescence imaging. Lab members have exploited the physics of reduced light scattering in the near-infrared-II (1000-1700nm) window and pioneered NIR-II fluorescence imaging to increase tissue penetration depth in vivo. Video-rate NIR-II imaging can measure blood flow in single vessels in real time. The lab has developed novel NIR-II fluorescence agents, including CNTs, quantum dots, conjugated polymers and small organic dyes with promise for clinical translation.

    Electrocatalysis and Batteries
    The Dai group’s nanocarbon–inorganic particle hybrid materials have opened new directions in energy research. Advances include electrocatalysts for oxygen reduction and water splitting catalysts including NiFe layered-double-hydroxide for oxygen evolution. Recently, the group also demonstrated an aluminum ion battery with graphite cathodes and ionic liquid electrolytes, a substantial breakthrough in battery science.

  • Heike Daldrup-Link

    Heike Daldrup-Link

    Professor of Radiology (General Radiology) and, by courtesy, of Pediatrics (Hematology/Oncology)

    Current Research and Scholarly InterestsAs a physician-scientist involved in the care of pediatric patients and developing novel pediatric molecular imaging technologies, my goal is to link the fields of nanotechnology and medical imaging towards more efficient diagnoses and image-guided therapies. Our research team develops novel imaging techniques for improved cancer diagnosis, for image-guided-drug delivery and for in vivo monitoring of cell therapies in children and young adults.

  • Gary Darmstadt

    Gary Darmstadt

    Professor (Teaching) of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology
    On Partial Leave from 07/01/2024 To 08/19/2024

    Current Research and Scholarly InterestsI have extensive experience in the development of global health innovations and in working to test and scale-up health interventions. At Stanford University, I am playing a leading role in developing global women and children’s health research and educational programs, including the establishment of a Global Center for Gender Equality at Stanford University. My research focuses on advancing child health and development in low resource settings and advancing gender equality and health globally, and includes several applications of artificial intelligence. Before joining Stanford, I was Senior Fellow at the Bill & Melinda Gates Foundation (BMGF), where I led the development of initiatives to address gender inequalities and empower women and girls. Prior to this role, I served as the BMGF Director of Family Health, leading strategy development and implementation across maternal, newborn and child health, nutrition, and family planning. In this role, I was responsible for investments ranging from scientific discovery to intervention development and delivery of interventions at scale. I worked closely with the Discovery team to shape discovery and development investments and was a co-founder of the Saving Lives at Birth Development Grand Challenge, the Putting Women and Girls at the Center of Development Grand Challenge, and the Healthy Birth, Growth and Development initiative. Based on these experiences, I understand how to identify knowledge gaps and generate evidence of impact for new interventions, and how to utilize evidence to influence the policy dialogue leading to programmatic adoption and scale-up of interventions in low income settings. As Director of Family Health, I also co-led the development and implementation of the BMGF global health strategy for India, which cuts across multiple health and development sectors. Before joining BMGF, I was Associate Professor and Founding Director of the International Center for Advancing Neonatal Health in the Department of International Health at the Johns Hopkins Bloomberg School of Public Health. I led the development of newborn health research, including numerous facility- and community-based maternal and child health research trials. Before joining Johns Hopkins, I was Senior Research Advisor for the $50M Saving Newborn Lives program of Save the Children-US, where I led the development and implementation of the global research strategy for newborn health and survival.

  • Rhiju Das

    Rhiju Das

    Professor of Biochemistry

    Current Research and Scholarly InterestsOur lab seeks an agile and predictive understanding of how nucleic acids and proteins code for information processing in living systems. We develop new computational & chemical tools to enable the precise modeling, regulation, and design of RNA and RNA/protein machines.

  • Reinhold Dauskardt

    Reinhold Dauskardt

    Ruth G. and William K. Bowes Professor in the School of Engineering

    BioDauskardt and his group have worked extensively on integrating new materials into emerging technologies including thin-film structures for nanoscience and energy technologies, high-performance composite and laminates for aerospace, and on biomaterials and soft tissues in bioengineering. His group has pioneered methods for characterizing adhesion and cohesion of thin films used extensively in device technologies. His research on wound healing has concentrated on establishing a biomechanics framework to quantify the mechanical stresses and biologic responses in healing wounds and define how the mechanical environment affects scar formation. Experimental studies are complimented with a range of multiscale computational capabilities. His research includes interaction with researchers nationally and internationally in academia, industry, and clinical practice.

  • Jenna Davis

    Jenna Davis

    Associate Dean for Integrative Initiatives in Institutes and International Partnerships, Professor of Civil and Environmental Engineering, at the Stanford Doerr School of Sustainability and Higgins-Magid Senior Fellow at the Woods Institute

    Current Research and Scholarly InterestsProfessor Davis’ research and teaching deals broadly with the role that water plays in promoting public health and economic development, with particular emphasis on low- and middle-income countries. Her group conducts applied research that utilizes theory and analytical methods from public and environmental health, engineering, microeconomics, and planning. They have conducted field research in more than 20 countries, most recently including Zambia, Bangladesh, and Kenya.

  • Mark M. Davis

    Mark M. Davis

    Director, Stanford Institute for Immunity, Transplantation and Infection and the Burt and Marion Avery Family Professor

    Current Research and Scholarly InterestsMolecular mechanisms of lymphocyte recognition and differentiation; Systems immunology and human immunology; vaccination and infection.

  • Vinicio de Jesus Perez MD

    Vinicio de Jesus Perez MD

    Associate Dean of Stanford MD Admissions and Professor of Medicine (PACCM)

    Current Research and Scholarly InterestsMy work is aimed at understanding the molecular mechanisms involved in the development and progression of pulmonary arterial hypertension (PAH). I am interested in understanding the role that the BMP and Wnt pathways play in regulating functions of pulmonary endothelial and smooth muscle cells both in health and disease.

  • Charles DeBattista

    Charles DeBattista

    Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology - Adult)

    Current Research and Scholarly InterestsTreatment resistant depression.

    Novel biological interventions in the treatment of mental illness.

    Anti-glucocorticoid drugs in the treatment of mood disorders.

    Augmentation strategies in the treatment of depression.

  • Thomas Dee

    Thomas Dee

    Barnett Family Professor, Professor of Education, Senior Fellow at the Stanford Institute for Economic Policy Research and, by courtesy, at the Hoover Institution

    BioThomas S. Dee, Ph.D., is the Barnett Family Professor at Stanford University’s Graduate School of Education (GSE), a Research Associate at the National Bureau of Economic Research (NBER), a Senior Fellow at the Stanford Institute for Economic Policy Research (SIEPR) and the Faculty Director of the John W. Gardner Center for Youth and Their Communities. His research focuses largely on the use of quantitative methods to inform contemporary issues of public policy and practice. The Association for Public Policy Analysis and Management (APPAM) awarded his collaborative research the Raymond Vernon Memorial Award in 2015 and again in 2019. He currently serves on the editorial boards of the American Educational Research Journal, the Journal of Policy Analysis and Management, and Education Finance and Policy.

  • Karl Deisseroth

    Karl Deisseroth

    D. H. Chen Professor, Professor of Bioengineering and of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsKarl Deisseroth's laboratory created and developed optogenetics, hydrogel-tissue chemistry (beginning with CLARITY), and a broad range of enabling methods. He also has employed his technologies to discover the neural cell types and connections that cause adaptive and maladaptive behaviors.

  • Scott L. Delp, Ph.D.

    Scott L. Delp, Ph.D.

    Director, Wu Tsai Human Performance Alliance at Stanford, James H. Clark Professor in the School of Engineering, Professor of Bioengineering, of Mechanical Engineering and, by courtesy, of Orthopaedic Surgery

    Current Research and Scholarly InterestsExperimental and computational approaches to study human movement. Development of biomechanical models to analyze muscle function, study movement abnormalities, design medical products, and guide surgery. Imaging and health technology development. Discovering the principles of peak performance to advance human health. Human performance research. Wearable technologies, video motion capture, and machine learning to enable large-scale analysis.

  • Utkan Demirci

    Utkan Demirci

    Professor of Radiology (Canary Cancer Center) and, by courtesy, of Electrical Engineering
    On Partial Leave from 02/26/2024 To 02/25/2025

    BioUtkan Demirci is a tenured professor in the School of Medicine at Stanford University and serves as the Interim Division Chief and Director of the Canary Center at Stanford for Cancer Early Detection in the Department of Radiology. Prior to Stanford, he was an Associate Professor of Medicine at the Brigham and Women’s Hospital, Harvard Medical School, and a faculty member of the Harvard-MIT Health Sciences and Technology division.

    Professor Demirci received his PhD from Stanford University in Electrical Engineering in 2005 and holds M.S. degrees in Electrical Engineering, and in Management Science and Engineering. He has published over 200 peer-reviewed journal articles, 24 book chapters, 7 edited books, and several hundred abstracts and proceedings, as well as having over 25 patents and disclosures pending or granted. He has mentored and trained hundreds of successful scientists, entrepreneurs and academicians and fostered research and industry collaborations around the world. Dr. Demirci was awarded the NSF CAREER Award, and IEEE EMBS Early Career Award. He is currently a fellow of the the American Institute for Medical and Biological Engineering (AIMBE, 2017), and Distinguished Investigator of the Academy for Radiology and Biomedical Imaging Research and serves as an editorial board member for a number of peer-reviewed journals.

    The BAMM Lab group focuses on developing innovative extracellular vesicle isolation tools, point-of-care technologies and creating microfluidic platforms for early cancer detection with broad applications to multiple diseases including infertility and HIV. Dr. Demirci’s lab has collaborated with over 50 research groups and industry partners around the world. His seminal work in microfluidics has led to the development of innovative FDA-approved platform technologies in medicine and many of his inventions have been industry licensed. He holds several FDA-approved and CE-marked technologies that have been widely used by fertility clinics with assisted reproductive technologies leading to over thousands of live births globally and in the US.

    Dr. Demirci is a serial academic entrepreneur and co-founder of DxNow, Zymot, Levitas Bio, Mercury Biosciences and Koek Biotech and serves as an advisor, consultant and/or board member to some early stage companies and investment groups.

  • Huiqiong Deng, MD, PhD

    Huiqiong Deng, MD, PhD

    Clinical Associate Professor, Psychiatry and Behavioral Sciences

    BioDr. Huiqiong Deng is a clinical associate professor of psychiatry. In addition to a medical degree, she earned a PhD, with a major in rehabilitation science and a minor in neuroscience. Specializing in the treatment of alcohol/substance addiction, interventional and cultural psychiatry, her goal is to help each patient along the journey to achieve optimal health and quality of life.

    As the co-author of more than a dozen scholarly articles, Dr. Deng’s work has appeared in Psychiatry Research, Journal of Studies on Alcohol and Drugs, American Journal on Addictions, Brain Stimulation, and other publications.

    Dr. Deng has won numerous honors and awards such as the National Institute on Drug Abuse Young Investigator Travel Award, the Ruth Fox Scholarship from the American Society of Addiction Medicine, and College on the Problems of Drug Dependence Travel Award for Early Career Investigators. In addition, she was selected to attend the Annual American Psychiatry Association Research Colloquium for Junior Investigators. Since she joined faculty at Stanford, Dr. Deng has received research grant support by the Department of Psychiatry and Behavioral Sciences Innovator Grant Program.

  • Jun Ding

    Jun Ding

    Associate Professor of Neurosurgery and of Neurology
    On Leave from 02/01/2024 To 07/31/2024

    Current Research and Scholarly InterestsNeural circuits of movement control in health and movement disorders

  • Jennifer Dionne

    Jennifer Dionne

    Professor of Materials Science and Engineering

    BioJennifer Dionne is the Senior Associate Vice Provost of Research Platforms/Shared Facilities and an Associate Professor of Materials Science and Engineering and of Radiology (by courtesy) at Stanford. Jen received her Ph.D. in Applied Physics at the California Institute of Technology, advised by Harry Atwater, and B.S. degrees in Physics and Systems & Electrical Engineering from Washington University in St. Louis. Prior to joining Stanford, she served as a postdoctoral researcher in Chemistry at Berkeley, advised by Paul Alivisatos. Jen's research develops nanophotonic methods to observe and control chemical and biological processes as they unfold with nanometer scale resolution, emphasizing critical challenges in global health and sustainability. Her work has been recognized with the Alan T. Waterman Award (2019), an NIH Director's New Innovator Award (2019), a Moore Inventor Fellowship (2017), the Materials Research Society Young Investigator Award (2017), Adolph Lomb Medal (2016), Sloan Foundation Fellowship (2015), and the Presidential Early Career Award for Scientists and Engineers (2014), and was featured on Oprah’s list of “50 Things that will make you say ‘Wow!'"

  • Scott Dixon

    Scott Dixon

    Associate Professor of Biology

    Current Research and Scholarly InterestsMy lab is interested in the relationship between cell death and metabolism. Using techniques drawn from many disciplines my laboratory is investigating how perturbation of intracellular metabolic networks can result in novel forms of cell death, such as ferroptosis. We are interested in applying this knowledge to find new ways to treat diseases characterized by insufficient (e.g. cancer) or excessive (e.g. neurodegeneration) cell death.

  • Diana Do, MD

    Diana Do, MD

    Professor of Ophthalmology

    Current Research and Scholarly InterestsDr. Do's research focuses on collaborative clinical trials to investigate novel treatments for retinal vascular diseases and ocular inflammation. She performs research to develop state of the art therapies for age-related macular degeneration, diabetic eye disease, retinal vein occlusion, retinal inflammation, and retinal detachment.

  • Sebastian Doniach

    Sebastian Doniach

    Professor of Applied Physics and of Physics, Emeritus

    Current Research and Scholarly InterestsStudy of changes in conformation of proteins and RNA using x-ray scattering

  • Les Dorfman, MD

    Les Dorfman, MD

    Professor of Neurology and Neurological Sciences, Emeritus

    Current Research and Scholarly InterestsClinical electrophysiology of the peripheral and central nervous systems, including nerve conduction velocity; electromyography (EMG); and visual, auditory and somatosensory evoked potentials. Multiple sclerosis (MS) diagnosis and treatment. Neurological education.

  • Anthony G. Doufas, M.D., Ph.D.

    Anthony G. Doufas, M.D., Ph.D.

    Professor of Anesthesiology, Perioperative and Pain Medicine

    Current Research and Scholarly InterestsMy research focuses on the relationship between sleep abnormalities and pain behavior and opioid pharmacology in the postoperative, as well as chronic pain setting. More specifically, I am interested in delineating the effect of the different components of sleep-diosordered breathing, like nocturnal recurrent hypoxemia and sleep fragmentation on pain behavior in the acute and/or chronic care setting.

  • Ron Dror

    Ron Dror

    Cheriton Family Professor and Professor, by courtesy, of Structural Biology and of Molecular & Cellular Physiology

    Current Research and Scholarly InterestsMy lab’s research focuses on computational biology, with an emphasis on 3D molecular structure. We combine two approaches: (1) Bottom-up: given the basic physics governing atomic interactions, use simulations to predict molecular behavior; (2) Top-down: given experimental data, use machine learning to predict molecular structures and properties. We collaborate closely with experimentalists and apply our methods to the discovery of safer, more effective drugs.

  • David Drover

    David Drover

    Professor of Anesthesiology, Perioperative and Pain Medicine
    On Partial Leave from 05/01/2024 To 01/31/2025

    Current Research and Scholarly InterestsField of clinical pharmacology. This involves analysis of what the body does to a drug (pharmacokinetics) and how exactly a specific drug affects the body (pharmacodynamics). His research starts at the level of new drug development with detailed analysis of the pharmacokinetics and pharmacodynamics of a medication.

  • Shaul Druckmann

    Shaul Druckmann

    Associate Professor of Neurobiology, of Psychiatry and Behavioral Sciences and, by courtesy, of Electrical Engineering

    Current Research and Scholarly InterestsOur research goal is to understand how dynamics in neuronal circuits relate and constrain the representation of information and computations upon it. We adopt three synergistic strategies: First, we analyze neural circuit population recordings to better understand the relation between neural dynamics and behavior, Second, we theoretically explore the types of dynamics that could be associated with particular network computations. Third, we analyze the structural properties of neural circuits.

  • Justin Du Bois

    Justin Du Bois

    Henry Dreyfus Professor of Chemistry and Professor, by courtesy, of Chemical and Systems Biology

    BioResearch and Scholarship

    Research in the Du Bois laboratory spans reaction methods development, natural product synthesis, and chemical biology, and draws on expertise in molecular design, molecular recognition, and physical organic chemistry. An outstanding goal of our program has been to develop C–H bond functionalization processes as general methods for organic chemistry, and to demonstrate how such tools can impact the logic of chemical synthesis. A second area of interest focuses on the role of ion channels in electrical conduction and the specific involvement of channel subtypes in the sensation of pain. This work is enabled in part through the advent of small molecule modulators of channel function.

    The Du Bois group has described new tactics for the selective conversion of saturated C–H to C–N and C–O bonds. These methods have general utility in synthesis, making possible the single-step incorporation of nitrogen and oxygen functional groups and thus simplifying the process of assembling complex molecules. To date, lab members have employed these versatile oxidation technologies to prepare natural products that include manzacidin A and C, agelastatin, tetrodotoxin, and saxitoxin. Detailed mechanistic studies of metal-catalyzed C–H functionalization reactions are performed in parallel with process development and chemical synthesis. These efforts ultimately give way to advances in catalyst design. A long-standing goal of this program is to identify robust catalyst systems that afford absolute control of reaction selectivity.

    In a second program area, the Du Bois group is exploring voltage-gated ion channel structure and function using the tools of chemistry in combination with those of molecular biology, electrophysiology, microscopy and mass spectrometry. Much of this work has focused on studies of eukaryotic Na and Cl ion channels. The Du Bois lab is interested in understanding the biochemical mechanisms that underlie channel subtype regulation and how such processes may be altered following nerve injury. Small molecule toxins serve as lead compounds for the design of isoform-selective channel modulators, affinity reagents, and fluorescence imaging probes. Access to toxins and modified forms thereof (including saxitoxin, gonyautoxin, batrachotoxin, and veratridine) through de novo synthesis drives studies to elucidate toxin-receptor interactions and to develop new pharmacologic tools to study ion channel function in primary cells and murine pain models.

  • Alfredo Dubra, PhD

    Alfredo Dubra, PhD

    Professor of Ophthalmology

    Current Research and Scholarly InterestsOur lab seeks to help the early diagnosing and monitoring progression of ocular, vascular, neurodegenerative and systemic diseases through novel non-invasive optical ophthalmic imaging. We pursue this goal through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines.

  • Laramie Duncan

    Laramie Duncan

    Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)

    Current Research and Scholarly InterestsWe study genetic and environmental effects on mental health. Much of our work is computational and it relies upon genetic data, collected from millions of individuals, from around the world. We use genetic approaches because the overall goal of the lab is to discover fundamental information about psychiatric disorders, and ultimately to build more rational approaches to classification, prevention, and treatment.

  • Alexander Dunn

    Alexander Dunn

    Professor of Chemical Engineering

    Current Research and Scholarly InterestsMy lab is deeply interested in uncovering the physical principles that underlie the construction of complex, multicellular animal life.

  • James Dunn

    James Dunn

    Professor of Surgery (Pediatric Surgery) and, by courtesy, of Bioengineering

    Current Research and Scholarly InterestsIntestinal lengthening for short bowel syndrome
    Intestinal stem cell therapy for intestinal failure
    Skin derived precursor cell therapy for enteric neuromuscular dysfunction
    Intestinal tissue engineering

  • Emmanuel During, MD

    Emmanuel During, MD

    Clinical Associate Professor, Neurology & Neurological Sciences

    Current Research and Scholarly InterestsImproving diagnostics and therapeutics in RBD, using home ambulatory devices including wearable actigraphy, dry-EEG, to power clinical trials based on objective outcomes of RBD activity.

    Controlling symptoms of RBD testing drugs rigorously.

    Predicting the course of neurodegeneration using deep phenotyping using clinical and serum biomarkers, measures of autonomic impairment, skin biopsy, microbiome