Wu Tsai Neurosciences Institute
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Assistant Professor of Psychology and, by courtesy, of Computer Science
Current Research and Scholarly InterestsOur lab's research lies at intersection of neuroscience, artificial intelligence, psychology and large-scale data analysis. It is founded on two mutually reinforcing hypotheses:
H1. By studying how the brain solves computational challenges, we can learn to build better artificial intelligence algorithms.
H2. Through improving artificial intelligence algorithms, we'll discover better models of how the brain works.
We investigate these hypotheses using techniques from computational modeling and artificial intelligence, high-throughput neurophysiology, functional brain imaging, behavioral psychophysics, and large-scale data analysis.
Associate Professor of Orthopaedic Surgery and of Bioengineering
Current Research and Scholarly InterestsOur research seeks to understand how microenvironmental cues regulate stem cell fate, and to develop novel biomaterials and stem cell-based therapeutics for tissue engineering and regenerative medicine. Our work spans from fundamental science, technology development, to translational research.We are particularly interested in developing better therapies for treating musculoskeletal diseases, cardiovascular diseases and cancer.
Associate Professor of Neurology
Current Research and Scholarly InterestsElucidate biological functions of cytoskeletal associated proteins in neurons. Define the cellular and molecular mechanisms underlying neurodegeneration in null mice.
Yunzhi Peter Yang
Associate Professor of Orthopaedic Surgery and, by courtesy, of Materials Science and Engineering
Current Research and Scholarly InterestsYangs research interests are based on bio-inspired biomaterials and approaches for re-creating a suitable microenvironment for cell growth and tissue regeneration, including enabling technology for bone regeneration, nanotechnology for dental and orthopedic implant devices, and naturally-based biomaterials for cancer treatment.
David C. Yeomans
Associate Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsPhysiology of different pain types; Biomarkers of pain and inflammation; Gene Therapy for Pain
Jared and Mae Tinklenberg Professor and Professor, by courtesy, of Neurology
Current Research and Scholarly InterestsWe study cognitive processes and aging in our research center. Studies range from molecular biology to neuropsychology of cognitive processes.
Jong H. Yoon
Associate Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult) at the Palo Alto Veterans Affairs Health Care System
Current Research and Scholarly InterestsMy research seeks to discover the brain mechanisms responsible for schizophrenia and to translate this knowledge into the clinic to improve how we diagnose and treat this condition. Towards these ends, our group has been developing cutting-edge neuroimaging tools to identify neurobiological abnormalities and test novel systems-level disease models of psychosis and schizophrenia directly in individuals with these conditions.
We have been particularly interested in the role of neocortical-basal ganglia circuit dysfunction. A working hypothesis is that some of the core symptoms of schizophrenia are attributable to impairments in neocortical function that results in disconnectivity with components of the basal ganglia and dysregulation of their activity. The Yoon Lab has developed new high-resolution functional magnetic resonance imaging methods to more precisely measure the function of basal ganglia components, which given their small size and location deep within the brain has been challenging. This includes ways to measure the activity of nuclei that store and control the release of dopamine throughout the brain, a neurochemical that is one of the most important factors in the production of psychosis in schizophrenia and other neuropsychiatric conditions.