Institute for Computational and Mathematical Engineering (ICME)

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  • Ali Mani

    Ali Mani

    Associate Professor of Mechanical Engineering

    BioAli Mani is an associate professor of Mechanical Engineering at Stanford University. He is a faculty affiliate of the Institute for Computational and Mathematical Engineering at Stanford. He received his PhD in Mechanical Engineering from Stanford in 2009. Prior to joining the faculty in 2011, he was an engineering research associate at Stanford and a senior postdoctoral associate at Massachusetts Institute of Technology in the Department of Chemical Engineering. His research group builds and utilizes large-scale high-fidelity numerical simulations, as well as methods of applied mathematics, to develop quantitative understanding of transport processes that involve strong coupling with fluid flow and commonly involve turbulence or chaos. His teaching includes the undergraduate engineering math classes and graduate courses on fluid mechanics and numerical analysis.

  • Alison Marsden

    Alison Marsden

    Douglass M. and Nola Leishman Professor of Cardiovascular Diseases, Professor of Pediatrics (Cardiology) and of Bioengineering and, by courtesy, of Mechanical Engineering

    Current Research and Scholarly InterestsThe Cardiovascular Biomechanics Computation Lab at Stanford develops novel computational methods for the study of cardiovascular disease progression, surgical methods, and medical devices. We have a particular interest in pediatric cardiology, and use virtual surgery to design novel surgical concepts for children born with heart defects.

  • Michaëlle Ntala Mayalu

    Michaëlle Ntala Mayalu

    Assistant Professor of Mechanical Engineering and, by courtesy, of Bioengineering

    BioDr. Michaëlle N. Mayalu is an Assistant Professor of Mechanical Engineering. She received her Ph.D., M.S., and B.S., degrees in Mechanical Engineering at the Massachusetts Institute of Technology. She was a postdoctoral scholar at the California Institute of Technology in the Computing and Mathematical Sciences Department. She was a 2017 California Alliance Postdoctoral Fellowship Program recipient and a 2019 Burroughs Wellcome Fund Postdoctoral Enrichment Program award recipient. She is also a 2023 Hypothesis Fund Grantee.

    Dr. Michaëlle N. Mayalu's area of expertise is in mathematical modeling and control theory of synthetic biological and biomedical systems. She is interested in the development of control theoretic tools for understanding, controlling, and predicting biological function at the molecular, cellular, and organismal levels to optimize therapeutic intervention.

    She is the director of the Mayalu Lab whose research objective is to investigate how to optimize biomedical therapeutic designs using theoretical and computational approaches coupled with experiments. Initial project concepts include: i) theoretical and experimental design of bacterial "microrobots" for preemptive and targeted therapeutic intervention, ii) system-level multi-scale modeling of gut associated skin disorders for virtual evaluation and optimization of therapy, iii) theoretical and experimental design of "microrobotic" swarms of engineered bacteria with sophisticated centralized and decentralized control schemes to explore possible mechanisms of pattern formation. The experimental projects in the Mayalu Lab utilize established techniques borrowed from the field of synthetic biology to develop synthetic genetic circuits in E. coli to make bacterial "microrobots". Ultimately the Mayalu Lab aims to develop accurate and efficient modeling frameworks that incorporate computation, dynamical systems, and control theory that will become more widespread and impactful in the design of electro-mechanical and biological therapeutic machines.

  • Parviz Moin

    Parviz Moin

    Franklin P. and Caroline M. Johnson Professor in the School of Engineering

    BioMoin is the founding director of the Center for Turbulence Research. Established in 1987 as a research consortium between NASA and Stanford, Center for Turbulence Research is devoted to fundamental studies of turbulent flows. Center of Turbulence Research is widely recognized as the international focal point for turbulence research, attracting diverse groups of researchers from engineering, mathematics and physics. He was the founding director of the Institute for Computational and Mathematical Engineering at Stanford.

    Professor Moin pioneered the use of direct and Large Eddy Simulation techniques for the study of turbulence physics, control and modelling concepts and has written widely on the structure of turbulent shear flows. His current interests include: Computational physics, Physics and control of turbulent boundary layers, hypersonic flows, propulsion, flow control, large eddy simulation for aerospace applications and aircraft icing.

  • Walter Murray

    Walter Murray

    Professor (Research) of Management Science and Engineering, Emeritus

    BioProfessor Murray's research interests include numerical optimization, numerical linear algebra, sparse matrix methods, optimization software and applications of optimization. He has authored two books (Practical Optimization and Optimization and Numerical Linear Algebra) and over eighty papers. In addition to his University work he has extensive consulting experience with industry, government, and commerce.