Maternal & Child Health Research Institute (MCHRI)
Showing 601-650 of 1,222 Results
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Stephanie A. Leonard
Assistant Professor (Research) of Obstetrics and Gynecology (Maternal Fetal Medicine) and, by courtesy, of Anesthesiology, Perioperative & Pain Medicine, and of Epidemiology and Population Health
BioStephanie Leonard, PhD, MS, is an Assistant Professor in the Dunlevie Maternal-Fetal Medicine Center for Discovery, Innovation, and Clinical Impact (https://dunleviemfm.stanford.edu/) and holds courtesy appointments in Anesthesiology, Perioperative and Pain Medicine and in Epidemiology and Population Health.
The goal of Dr. Leonard’s research is to advance positive health outcomes and experiences for pregnant individuals and newborns. She is interested in applying transdisciplinary methods to perinatal health research, with a focus on studying pregnancy-related morbidities in large data sources. Currently, her primary research interests are in utilizing large electronic health record datasets to conduct multi-site studies on chronic health condition treatments during pregnancy. To this end, she co-launched the OHDSI Pregnancy and Reproductive Health Work Group (https://www.ohdsi.org/workgroups/) and collaborates closely with the Harvard Program on Perinatal and Pediatric Pharmacoepidemiology (http://www.harvardpreg.org/). She also serves as a collaborator and mentor on a variety of obstetrics studies, including clinical trials, prospective and retrospective observational studies, and qualitative studies. Dr. Leonard's research program is currently funded by NHLBI (K01) and NICHD (U54).
Dr. Leonard trained in epidemiology at UCLA (MS) and UC Berkeley (PhD), where her research focused on nutrition in pregnancy. She completed a postdoc in Neonatal and Developmental Medicine at Stanford as part of the Stanford Center for Population Health Sciences. -
Marc Levenston
Associate Professor of Mechanical Engineering and, by courtesy, of Radiology (Radiological Sciences Laboratory)
Current Research and Scholarly InterestsMy lab's research involves the function, degeneration and repair of musculoskeletal soft tissues, with a focus on meniscal fibrocartilage and articular cartilage. We are particularly interested in the complex interactions between biophysical and biochemical cues in controlling cell behavior, the roles of these interactions in degenerative conditions such as osteoarthritis, and development of tissue engineered 3D model systems for studying physical influences on primary and progenitor cells.
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Maayan Levy
Assistant Professor of Pathology
Current Research and Scholarly InterestsThe Levy Lab studies how microbiome-brain interactions influence metabolism, behavior, and disease. By investigating how microbial signals affect neural circuits, we explore mechanisms underlying obesity, diabetes, and psychiatric conditions. The lab seeks to uncover new therapeutic targets using advanced neuroscience tools like optogenetics and imaging. Our research aims to improve understanding of how microbiome imbalances contribute to disease and how restoring balance can promote health.
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David B. Lewis
Naddisy Foundation Professor of Pediatric Food Allergy, Immunology, and Asthma
Current Research and Scholarly InterestsMy laboratory is focused on defining cellular and molecular mechanisms that limit T cell responses to vaccines and pathogens during normal early postnatal development and in cases of inherited genetic immunodeficiencies. We are also determinomg how these limitations in immunity can be overcome by using novel approaches for vaccine adjuvants for influenza vaccine and by using catalytically inactive Cas proteins for inducing endogenous gene expression.
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Gordon Li, MD
Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences and of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly Interests1.) My laboratory studies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant brain tumors and translating that research into clinical trials.
2.) My clinical interests include improving surgical techniques for brain tumor surgery, immunotherapy for the treatment of glioblastoma, and novel uses for stereotactic radiosurgery. -
Jin Billy Li
Professor of Genetics
Current Research and Scholarly InterestsThe Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.
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Joseph C. Liao
Kathryn Simmons Stamey Professor
Current Research and Scholarly InterestsThe overarching theme of my scholarship is to develop precision diagnostics in imaging and biomarkers to guide the delivery of precision therapy for urological diseases including bladder cancer, urinary tract infections, and kidney stone disease.
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Ronglih Liao
Douglass M. and Nola Leishman Professor of Cardiovascular Disease
BioDr. Liao is a Professor of Medicine and co-Director of Stanford Cardiac Amyloid Center. The major goal of her research program focuses on understanding the mechanisms that underlie the pathophysiology of heart failure and developing novel treatments to combat this process. Her laboratory has played an international leading role in the study of amyloid light chain (AL) cardiomyopathy, a rare and fatal form of cardiovascular disease. We have described the underlying pathophysiologic basis for amyloid cardiomyopathy and found that the circulating amyloidogenic light chain proteins that characterize this disease directly result in a specific cardiotoxic response. Consequently, our research work has redefined AL cardiomyopathy and has raised new treatment approaches. More recently, her research efforts have expanded to include transthyretin (ATTR) cardiac amyloidosis.
In line with her goal of revealing novel therapeutic strategies for patients with cardiovascular disease, our efforts have also focused on characterizing and harnessing endogenous cardiac regenerative mechanisms. Her laboratory initially demonstrated the therapeutic potential of exogenous primitive muscle cells delivered to the injured heart. This work was among the earliest milestones in the field and served as the basis for an international trial of cell-based therapy. Subsequently, Liao lab identified and characterized a population of cardiac progenitor cells and its relationship and dynamic activity following cardiac injury in the adult heart. Her laboratory aims to reveal the molecular mechanisms regulating the endogenous regenerative capacity of the heart and to harness such repair mechanisms for the treatment of cardiovascular disease. Dr. Liao has lectured extensively on both amyloid cardiomyopathy and stem cell biology, and have maintained a history of independent NIH funding in these areas for more than two decades.
Over the course of her academic career, she has taken the greatest pride in mentoring the next generation of scientists. Dr. Liao has had the privilege to supervise several dozen students, postdoctoral fellows, and junior faculty, many of whom have gone on to independent academic careers at the highest institutions. Her contribution to the advancement of scientific knowledge also includes lecturing at various university and academic institutions as well as at scores of conferences and symposia locally, nationally, and internationally. -
Y. Joyce Liao, MD, PhD
Stanford Medicine Professor of Ophthalmology and Professor of Neurology and Neurological Sciences
Current Research and Scholarly InterestsIschemic optic neuropathy
Stem cell transplantation
Optic neuropathy
Optic neuritis
Eye movement disorders
Reading
Parkinson's disease
Multiple sclerosis -
Michael Lin
Professor of Neurobiology, of Bioengineering and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur lab applies biochemical and engineering principles to the development of protein-based tools for investigating biology in living animals. Topics of investigation include fluorescent protein-based voltage indicators, synthetic light-controllable proteins, bioluminescent reporters, and applications to studying animal models of disease.
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Bruce Ling
Senior Research Scientist, Pediatrics - Neonatology
Current Research and Scholarly InterestsMy research focuses on developing AI-enabled translational medicine platforms that integrate real-world electronic health records, wearable biosensor signals, LC-MS/MS-based proteomics and metabolomics, cfDNA molecular profiling, and multimodal medical imaging. The overarching goal is to transform longitudinal clinical, physiological, and molecular data into predictive tools for early disease detection, dynamic risk stratification, digital twin modeling, and precision intervention.
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Michael Link
Lydia J. Lee Professor of Pediatric Cancer
Current Research and Scholarly InterestsHematology/Oncology, treatment of sarcomas of bone and soft tissue, biology of acute lymphoblastic leukemias, treatment of non-Hodgkin's lymphoma and Hodgkin's disease.
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Eleni Linos, MD, MPH, DrPH
Ben Davenport and Lucy Zhang Professor of Medicine, Professor, of Medicine (Center for Digital Health) and, by courtesy, of Epidemiology and Population Health
BioEleni Linos MD, MPH, DrPH, is the Director of the Stanford Center for Digital Health. Dr. Linos serves as Associate Dean for Research and Professor of Dermatology and Epidemiology at Stanford Medicine.
Dr. Linos' research focuses on the use of technology in health, dermatology, public health, cancer prevention and the care of older adults. She is dually trained in epidemiology and dermatology and is the principal investigator of several NIH funded studies aimed at improving the lives of patients worldwide. She received her undergraduate degree from Trinity College, Cambridge and medical degree from Christ Church College, Oxford University in the UK. She then received a master’s and doctoral degree from the Harvard School of Public Health and completed her residency in Dermatology at Stanford University.
Linos has been continuously funded by the NIH since 2016, as principal investigator of several studies on technology, aging and dermatology. Her scholarly output includes over 200 peer-reviewed publications, an h-index of 51, and more than 10,000 citations across disciplines. Linos was awarded the NIH Director’s New Innovator Award and received the Paul Beeson Emerging Leaders Award in Aging.
As the Director of the Stanford Center for Digital Health, she has built and led infrastructure bringing together scientists and industry leaders across all Stanford schools to catalyze research across the fields of medicine, computer science, engineering, robotics, policy and public health.
Dr. Linos is committed to mentorship and training of the next generation of scientists in translational research. She has personally mentored over 60 physician-scientists, many of whom are now independently-funded investigators and leaders in academic medicine. She also serves as the co-PI of Stanford CTSA’s K12 Program, responsible for mentorship and training of 10 translational science faculty each year. Over the last seven years, she is funded by an NIH K24 mentorship grant award to mentor the next generation of physician-scientists in dermatology. In addition, Linos is committed to mentorship and supporting students across all levels of education to pursue their passions including students in high school and undergraduates.
Clinically, Dr. Linos is a Board Certified Dermatologist and cares for patients with skin disease in the Stanford Dermatology teaching clinics. -
Joseph (Joe) Lipsick
Professor of Pathology and of Genetics
Current Research and Scholarly InterestsFunction and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.
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Jonathan Samuel Litt
Associate Professor of Pediatrics (Neonatal and Developmental Medicine) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsMy research program has two distinct though closely related areas of focus. The first concerns understanding pathways through which chronic health problems impact behavioral development and functional outcomes among preterm infants. I am particularly interested in how neonatal multimorbidity and associated markers of epigenetic aging can help improve risk-prediction for long-term functional outcomes. My second area of academic focus is bringing health services research and improvement science approaches to studying the delivery of high-risk infant follow-up and developing innovative models of post-discharge care. This work includes a focus on population health management, value-based care, and equity-focused quality improvement.
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Anne Liu
Clinical Professor, Pediatrics - Immunology
Clinical Associate Professor (By courtesy), Medicine - Pulmonary, Allergy & Critical Care MedicineBioDr. Liu is a board-certified, fellowship-trained specialist in allergy/immunology and infectious disease. She is also a clinical associate professor in the Department of Medicine, Division of Infectious Diseases and the Department of Pediatrics, Division of Allergy, Immunology, and Rheumatology at Stanford University School of Medicine.
Dr. Liu treats infections in patients with compromised immune systems, whether due to a primary immune deficiency or a condition like cancer or organ transplant. She helps patients to develop tolerance to medications they are allergic to so that they can receive the best, and sometimes the only, treatments available to them. She also treats allergies to antibiotics, aspirin, NSAIDs, chemotherapy, and more. She sees patients both long term and for urgent referrals, such as in cases of perioperative anaphylaxis. Dr. Liu also helps pediatric patients manage drug and food allergies.
One of Dr. Liu’s areas of focus is helping patients with allergies to antibiotics determine when they have lost an allergy, what antibiotics they can tolerate, and when to induce tolerance to an antibiotic. This not only can benefit the patient, but also have a positive public health impact, as labeling patients with a penicillin allergy may negatively affect their care and increase use
of broad-spectrum antibiotics.
She collaborates closely with colleagues from other disciplines, including pulmonology, otolaryngology, oncology, cardiology, dermatology, anesthesiology, and surgery. Her key objective in working with referring physicians is to help them safely deliver the best care for their patients.
For patients and families, Dr. Liu strives to help them navigate their care journey with as much ease and dignity as possible during what may be the most challenging time of their life. Her goal is to offer patients options, even when it may appear that they have no options left.
Dr. Liu’s research interests include optimizing care of patients with antibiotic allergies, including through use of decision support tools.
Dr. Liu has authored articles in the New England Journal of Medicine, Journal of Immunology, Journal of Allergy and Clinical Immunology in Practice, Clinical and Experimental Allergy, Mucosal Immunology, Diagnostic Microbiology and Infectious Disease, Science, and other publications. Dr. Liu authored the book chapter “Hypersensitivity Reactions to Monoclonal Antibodies” in Drug Allergy Testing.
Dr. Liu is certified in infectious disease by the American Board of Internal Medicine and in allergy and immunology by the American Board of Allergy and Immunology. She is also a member of the American College of Physicians, Infectious Diseases Society of America, and American Academy of Allergy, Asthma, and Immunology.
She has given presentations on antibiotic allergies, drug desensitization, and aspirin-exacerbated respiratory disease, among other topics. Dr. Liu’s honors include recognition from the American Academy of Asthma, Allergy, and Immunology, the American Medical Women’s Association, and the National Institutes of Health. -
Lili Liu
Postdoctoral Scholar, Epidemiology
BioLili (Larry) Liu, PhD, is a postdoctoral fellow in the Department of Epidemiology and Population Health at Stanford University. Dr. Liu is an integrative epidemiologist whose research is unified by a consistent methodological approach rather than a single disease area. Across his master’s, doctoral, and postdoctoral training, he has repeatedly developed or operationalized epidemiologic frameworks and analytic programs and applied them to important public health questions spanning rare diseases, chronic disease, cancer, mortality, microbiome, and women’s health. His work brings together molecular biomarkers, large-scale population cohorts, and real-world health data to generate coherent, hypothesis-driven research on how genetic variation, lifestyle, pharmacologic factors, and early-life exposures shape inflammation, biological aging, and chronic disease risk across the life course.
During his master’s training at Peking University, Dr. Liu developed expertise in literature synthesis, national claims-based study, rare disease burden estimation, patient-centered health information research, cohort-based analysis, and vaccine effectiveness evaluation. He helped build and apply claims-based analytic algorithms to estimate incidence and prevalence for multiple rare diseases in China, led first-author studies on online health information and patient information needs in rare disease populations, and established an analytic framework for CHARLS-based cohort studies that supported multiple downstream projects. During his PhD training at Vanderbilt University, he expanded into population genetics, molecular and cancer epidemiology, mortality and health disparities research, gut microbiome, and pooled multi-study analyses. His doctoral work included a multi-ancestry GWAS of urinary prostaglandin E2 metabolite (PGE-M), development of PGE-M-derived dietary and lifestyle scores, and Mendelian randomization analyses linking lipid-related pathways to colorectal cancer risk. He also led several first-author studies in the Southern Community Cohort Study on poverty, sitting time, physical activity, walking and mortality, and alcohol intake and the gut microbiome, several of which received substantial public health and media attention.
At Stanford, Dr. Liu has developed an independent research program centered on women’s health and life-course epidemiology using U.S. national claims data. He has built large nationwide pregnancy and mother-baby cohorts from MarketScan to study adverse obstetric outcomes, long-term cardiometabolic and hepatic outcomes, and early-onset cancer risk. His first corresponding-author paper at Stanford examined gestational diabetes in relation to subsequent type 2 diabetes and metabolic dysfunction-associated steatotic liver disease, and his ongoing work extends this framework to cardiovascular, kidney, metabolic, and reproductive health outcomes, including PCOS and endometriosis. He also received a Stanford MCHRI fellowship grant to study prenatal and early-life antibiotic exposure in relation to pediatric inflammatory bowel disease and celiac disease. In parallel, his collaborative work includes placental and maternal-fetal research on extracellular vesicles and angiogenic signaling.
Methodologically, Dr. Liu works at the interface of causal inference, pharmacoepidemiology, molecular epidemiology, and scalable real-world data science, using reproducible analytic pipelines in R, Python, SQL, and high-performance computing environments. Across all stages of his training, the central theme of his work has been to build scalable analytic infrastructure and apply it to high-impact epidemiologic questions with broad public health relevance, with the overarching goal of translating rigorous population science into actionable strategies for chronic disease prevention in diverse populations. -
Lin Liu
Postdoctoral Scholar, Chemistry
BioI finished my undergraduate study in general chemistry at Shandong Normal University in 2014. Later, I continued to my master’s studies in organic chemistry at Lanzhou University. In 2018, I moved to Baylor University conducting research under the mentorship of Professor John L. Wood. During my graduate studies, I mainly focused on the total syntheses of natural products. In 2024, I joined the Khosla lab and Cui lab as a joint postdoc. Outside the lab, I like cooking, playing basketball, and watching movies
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Wendy Liu, MD, PhD
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsDr. Liu's research interests include the role of mechanosensation in the eye as it relates to the pathophysiology of glaucoma, with the goal of finding new druggable targets in glaucoma treatment.
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Nathan Lo
Assistant Professor of Medicine (Infectious Diseases) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsOur research group is interested in studying the transmission of infectious diseases and impact of public health interventions with an ultimate goal of informing public health policy. We study a diverse set of pathogens, both domestically and internationally, including vaccine-preventable infections (including COVID-19) and neglected parasitic diseases (such as schistosomiasis). Our group applies diverse computational methodologies, including tools from fields of epidemiology, mathematical and statistical modeling, simulation, and policy analysis.
A large emphasis of our work is translating scientific evidence into public health policy. Our track record includes multiple studies that have changed policy in the fields of neglected parasitic diseases and COVID-19. We work closely with policy organizations like the World Health Organization and the California Department of Public Health. Nathan was the lead writer of the World Health Organization guidelines on schistosomiasis (2022) and strongyloidiasis (2024).
Our current research focuses on the following areas:
(1) Vaccine-preventable infectious diseases (including COVID-19 and measles) in the United States, with a focus on studying vaccines, transmission dynamics, and re-emergence of vaccine-eliminated diseases
(2) Public health strategies for control and elimination of globally important neglected infectious diseases, such as helminths infections (schistosomiasis, strongyloidiasis) and typhoid fever
Our current NIH funded projects include:
(1) Real-time predictive modeling for public health departments to control infectious diseases (DP2 AI170485, PI: Lo)
(2) Precision mapping of Schistosoma mansoni risk for targeted public health control and elimination (R01 AI179771, PI: Lo)
Hiring
We are seeking to fill multiple research positions at all levels. Candidates interested in working on computational public health research related to infectious diseases with a strong quantitative background are highly encouraged to apply. If you an interested, please submit a cover letter, CV, and names of two references to Nathan.Lo@stanford.edu. -
James Lock
Eric Rothenberg, MD Professor and Professor, by courtesy, of Pediatrics
Current Research and Scholarly InterestsJames Lock, MD, Ph.D. is Professor of Child Psychiatry and Pediatrics in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine where he has taught since 1993. He is board certified in adult as well as child and adolescent psychiatry. He directs the eating disorder program in Child Psychiatry and is active in treatment research for children and adolescents with eating disorders.
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Kyle Loh
Associate Professor of Developmental Biology (Stem Cell)
BioHow the richly varied cell-types in the human body arise from one embryonic cell is a marvel and mystery. We have mapped how human embryonic stem cells develop into over twenty different types of cells. This roadmap allowed us to generate enriched populations of human brain, blood, blood vessel, bone, and other cells in a Petri dish from embryonic stem cells, with implications for developmental biology, stem cell biology, and regenerative medicine. Additionally, we have an emerging interest in exploring deadly biosafety level 4 viruses together with our collaborators.
Kyle attended the County College of Morris and Rutgers, and received his Ph.D. from Stanford (working with Irving Weissman), with fellowships from the Hertz Foundation, National Science Foundation and Davidson Institute for Talent Development. He then continued as a Siebel Investigator, and later, as an faculty member at Stanford. Kyle is a Packard Fellow, Pew Scholar, Human Frontier Science Program Young Investigator and Baxter Foundation Faculty Scholar. His research has been recognized by the NIH Director's Early Independence Award, ISSCR Early Career Impact Award, Forbes 30 Under 30, Harold Weintraub Graduate Award, Hertz Foundation Thesis Prize and A*STAR Investigatorship. -
Adrienne H. Long, MD, PhD
Instructor, Pediatrics - Hematology & Oncology
BioAdrienne H. Long, MD, PhD is an Instructor and Physician-Scientist in the Division of Pediatric Hematology and Oncology at the Lucile Packard Children's Hospital, Stanford. Clinically, she completed her MD at Northwestern University, her pediatrics residency at Boston Children’s Hospital, and her oncology fellowship training at Stanford University. Dr. Long sees patients with leukemias/lymphomas, and has a clinical interest in T cell malignancies.
Dr. Long received her PhD in Microbiology/Immunology through a National Institutes of Health (NIH) – Northwestern University partnership, where she worked with Dr. Crystall Mackall to advance CAR T cell therapies. Her influential thesis work was the first to identify T cell exhaustion as a critical factor limiting efficacy of CAR therapies (Long et al., Nature Medicine, 2015). She continued her research training with Dr. Nicholas Haining at the Dana Farber Cancer Institute during residency and is currently conducting her post-doctoral research with Dr. Mark Davis at Stanford.
Dr. Long’s research interests lie at the intersection of the immune system and cancer therapies. She is currently studying how thymic selection, designed to prevent auto-immunity, may also inhibit anti-tumor immunity in children. She is also interested in how immunotherapies that have revolutionized how we treat cancer can impact the developing pediatric immune system long term. -
Jonathan Z. Long
Associate Professor of Pathology
BioDr. Jonathan Long is an Associate Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). His laboratory studies the molecular mechanisms of mammalian energy homeostasis. Dr. Long is the recipient of the Alfred P. Sloan Research Fellowship in Chemistry, the Breakthrough Sciences Award from the Ono Pharma Foundation, and the NIDDK Catalyst Award. Prior to arriving to Stanford, Dr. Long completed his Ph.D. in Chemistry at Scripps Research and his postdoctoral work at Harvard Medical School.
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Dr. Michael T. Longaker
Deane P. and Louise Mitchell Professor in the School of Medicine and Professor, by courtesy, of Materials Science and Engineering
Current Research and Scholarly InterestsWe have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2) Distraction Osteogenesis, 3) Fibroblast heterogeneity and fibrosis repair, 4) Scarless Fetal Wound Healing, 5) Skeletal Stem Cells, 6) Novel Gene and Stem Cell Therapeutic Approaches.
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Billy W Loo Jr, MD PhD FASTRO FACR
Professor of Radiation Oncology (Radiation Therapy)
Current Research and Scholarly InterestsMy clinical specialty is precision targeted radiotherapy of thoracic cancers.
My research is on developing next-generation ultra-rapid radiotherapy technology (PHASER) and studying the radiobiological effects of FLASH treatment.
My clinical research is on advanced 4-D image-guided radiotherapy and stereotactic ablative radiotherapy (SABR), and functional and metabolic imaging and imaging biomarkers. -
Alarice Cheng-Yi Lowe
Associate Professor of Pathology
BioDr. Lowe joined the School of Medicine faculty in 2019. She received her undergraduate degree in Biology from MIT and her medical degree at UCSD, prior to residency and cytology fellowship at UCLA. In 2011, she joined the faculty at Brigham and Women's Hospital where she developed a research focus on Circulating Tumor Cells (CTCs) and the application of new technology to improve clinical and molecular diagnostics. Clinically, her interests focus on Cytopathology and Genitourinary Pathology.
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Lu,Guolan
Assistant Professor of Urology
Current Research and Scholarly InterestsThe Lu Lab develops and integrates AI, spatial multi-omics, and advanced imaging to understand and model how cells, tissues, and therapeutic agents interact in their native spatial context, and how these interactions drive disease progression and treatment response.
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Sydney X. Lu
Assistant Professor of Medicine (Hematology)
BioSydney Lu is an assistant professor and physician-scientist in the Division of Hematology, Department of Medicine with a broad interest in both normal and abnormal RNA processing in the context of normal physiology and disease states. The laboratory studies translational questions regarding the mechanistic basis of RNA processing abnormalities in malignant blood disorders, their implications for leukemogenesis and cancer biology, as well as resultant therapeutic opportunities.
As a physician, Sydney’s group is particularly focused on dissecting RNA processing abnormalities in primary patient samples and disease-relevant preclinical model systems. Lab members employ a variety of ‘wet-lab’ and computational approaches to study transcriptome abnormalities in (1) states of immune dysfunction, (2) myeloid blood cancers such as myelodysplastic syndromes and acute myeloid leukemia, and (3) lymphoid blood cancers such as chronic lymphocytic leukemia. Additional projects are focused on novel therapeutics, including multiple targeted agents which modulate RNA processing, for the selective treatment of these diseases.
Sydney’s research is/has been supposed by grant funding from the National Cancer Institute, Parker Institute for Cancer Immunotherapy, Leukemia & Lymphoma Society, Aplastic Anemia & Myelodysplastic Syndromes International Foundation, the American Society for Clinical Oncology, the American Society of Hematology, the American Association for Cancer Research, the Paula and Rodger Riney Foundation, the Doris Duke Charitable Foundation, The Gabrielles Angel Foundation for Cancer Research, and the Stanford Cancer Institute. -
Stephen Luby
Lucy Becker Professor of Medicine, Senior Fellow at the Woods Institute for the Environment, Freeman Spogli Institute for International Studies and Professor, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsDr. Luby’s research interests include identifying and interrupting environmental pathways of disease in low- and middle-income countries.
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Chase A. Ludwig, MD, MS
Assistant Professor of Ophthalmology (Research/Clinical Trials)
Current Research and Scholarly InterestsMy research focuses on understanding high and pathologic myopia and their retinal sequelae, including retinal detachments, myopic traction maculopathy, and myopic macular degeneration. By leveraging informatics and big data analytics, I aim to uncover strategies that prevent and treat the progression of these complex and devastating conditions. My work takes advantage of the retina’s unique role as the only visible portion of the central nervous system, allowing for discoveries in ophthalmology that have the potential to impact broader fields of medicine.
I am actively seeking medical students and residents interested in ophthalmology or vitreoretinal surgery to assist with writing projects and data analytics. If you are passionate about advancing the understanding and management of myopia, I invite you to join me in tackling one of the most pressing global challenges in eye care.
