Maternal & Child Health Research Institute (MCHRI)
Showing 481-490 of 1,229 Results
-
John Huguenard
Professor of Neurology and Neurological Sciences (Neurology Research), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology
Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.
-
Wouter Huiting
Postdoctoral Scholar, Chemical and Systems Biology
BioWouter received his training at the University of Groningen, the Netherlands. Here he obtained a B.Sc.and M.Sc. in Human Movement Sciences (2008-2015), followed by a M.Sc. in Clinical and Molecular Neurosciences (2014-2016). He performed his doctoral research at the University of Groningen, obtaining his PhD degree in Molecular Cell Biology in 2021. Wouter continued his research in 2022 with a position as postdoctoral scholar at the Jarosz lab, at the department of Chemical and Systems Biology. Here he pursues his interest in the molecular forces underlying proteomic adaptation of cells and systems in development and disease. Outside of Stanford, Wouter is an avid sportsman, and likes cooking, hiking, birding, and in general loves to enjoy nature and wildlife with his wife and son.
-
Noor A. Hussein
Postdoctoral Scholar, Medicine
Current Research and Scholarly InterestsMy current work aims to increase the understanding of pediatric acute onset neuropsychiatric disorder (PANS) disease mechanism and to improve the treatment options. It focuses on studying the alteration of regulatory T cells (Tregs), which are key inhibitors of autoimmunity and main regulator of inflammation, in PANS.
-
Duc Tan Huynh
Postdoctoral Scholar, Neurosurgery
BioAs a cell biologist interested in neuroscience, I am fascinated about the molecular basis of nervous system disorders that reveal therapeutic targets and/or biomarkers. My long-term research goal is to identify strategies that revert dysregulation in aging or neurodegeneration. For my postdoctoral training in the Zuchero lab (Neurosurgery), I will investigate how myelination, an essential developmental process, contributes to intelligence and neurodegeneration at the biochemical, cellular, and physiological level. I received my BSc at UCLA and my PhD at Duke University.
-
Irogue I Igbinosa
Assistant Professor of Obstetrics and Gynecology (Maternal Fetal Medicine & Obstretrics)
BioIrogue Igbinosa, MD, MS, is a Maternal-Fetal Medicine physician at Stanford University. Her research focus includes iron deficiency anemia in pregnancy, severe maternal morbidity and mortality, and health equity. She is a NIH Women's Reproductive Health Scholar (K12) and recently, she was also recognized as the Duan Family Faculty Scholar in Maternal-Fetal Medicine.
She graduated from the University of Houston and earned her medical degree at Baylor College of Medicine. She subsequently completed her residency in Obstetrics and Gynecology Residency at Louisiana State University School of Medicine Baton Rouge. After residency, she was an AAMC-CDC Public Health Policy Fellow able to serve in the CDC Emergency Operations Center and contribute to research for healthcare providers regarding the management of the Zika virus in pregnant persons. She completed her Maternal Fetal Medicine fellowship at Stanford in 2022.
Dr. Igbinosa is passionate about community-engaged approaches to bridge gaps in evidence-based care for birthing communities and collaborates with local and national policy committees to raise awareness for reproductive justice in maternal health. In 2023, 2he was awarded the inaugural Maternal Health Implementation Science Physician Research Scholar with AMETHIST @Penn (Achieving Maternal Empowerment and Transforming Health at University of Pennsylvania) and applies to the principles learned to many aspects of her ongoing research. Her current research endeavors include co-investigator for Stanford's PHRISM: preventing inequities in hemorrhage related severe maternal morbidity, primary investigator for NOURISH - prenatal nutrition education for community health workers and doulas, as well as several hospital quality initiative efforts to improve the screening, management, and treatment of iron deficiency anemia in pregnancy. Her motto is to listen first and serve with compassion. -
Gentaro Ikeda
Instructor, Medicine - Cardiovascular Medicine
BioDr. Ikeda is a physician-scientist who develops innovative diagnostic and therapeutic modalities for patients with cardiovascular disease. Based on his clinical experience as a cardiologist, he has become aware of major clinical shortcomings, specifically in the current pharmaceutical therapies for myocardial infarction (MI) and chronic heart failure (HF). Some evidence-based drug therapies, including β-blockers, ivabradine, and renin-angiotensin-aldosterone antagonists are difficult to apply to critical patients due to adverse side effects. Drugs that have shown efficacy in basic animal experiments have failed to show significant benefits in clinical trials. To address these problems, he moved to academia to conduct translational research. During his graduate training in the Egashira Lab, he focused on drug delivery systems (DDS) that target mitochondria in animal models of MI. He obtained advanced skills in molecular biology, mitochondrial bioenergetics, and animal surgery. He realized the importance of translational research and the great potential of DDS to overcome many clinical problems. He developed nanoparticle-mediated DDS containing cyclosporine for the treatment of patients with MI. He published a first-author paper and received academic awards for his novel science. Since becoming a postdoctoral fellow in the Yang Lab, he has continued to build upon his previous training in translational research. He is currently developing an innovative therapy, namely, extracellular vesicles-mediated mitochondrial transfer for mitochondria-related diseases such as heart failure and mitochondrial disease.
-
Jennifer Ikle
Adjunct Clinical Assistant Professor, Pediatrics - Endocrinology
Current Research and Scholarly InterestsJen is interested in the genetic factors that lead to abnormal beta-cell function and insulin secretion, causing disorders such as hyperinsulinism and neonatal diabetes. Jen’s current research focus is the use of zebrafish models, combined with genetics and genomics, to understand cellular and molecular mechanisms of glucose metabolism and elucidate previously unknown players involved in the regulation of insulin secretion.
-
Daniel Imler
Clinical Associate Professor, Emergency Medicine
Clinical Associate Professor, PediatricsCurrent Research and Scholarly InterestsI am interested in understanding the impact of smart, agile clinical pathways to drive behavior change among providers.
-
Amy M Inkster
Postdoctoral Scholar, Epidemiology
BioAmy Inkster, PhD is a Postdoctoral Scholar in the Department of Epidemiology and Population Health at Stanford University. She conducts research on epigenetic alterations in pregnancy and early life to understand the molecular levers affecting healthy development. She primarily uses large 'omics datasets to study the effect of environmental exposures on pregnancy outcomes and maternal health.
Dr. Inkster received her PhD in Medical Genetics from the University of British Columbia (Vancouver, Canada), where her research focused on evaluating DNA methylation variation in prenatal life, primarily in the context of placental epigenetics, sex differences, prenatal exposures, and X-chromosome inactivation. She holds a BSc in Chemistry. As a cross-disciplinary researcher, her work and research interests lie at the intersection of molecular mechanisms and their impacts on human health and disease at the population level. -
Peter K. Jackson
Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Current Research and Scholarly InterestsDr. Jackson’s lab studies how primary cilia organize hormone, metabolite, and growth factor signaling in metabolic tissues and how their disruption causes obesity and diabetes. A second focus is defining the KRAS driven secreted factor networks that rewire the tumor microenvironment in lung and pancreatic cancers to promote immune evasion and therapeutic resistance. This work is revealing new secreted drug targets and combination strategies for precision oncology and metabolic disease.