School of Medicine
Showing 1-7 of 7 Results
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Julien Sage
Elaine and John Chambers Professor of Pediatric Cancer and Professor of Genetics
Current Research and Scholarly InterestsWe investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.
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Serena Sanulli
Assistant Professor of Genetics
Current Research and Scholarly InterestsWe study the organizing principles of the genome and how these principles regulate cell identity and developmental switches. We combine Biochemistry and Biophysical methods such as NMR and Hydrogen-Deuterium Exchange-MS with Cell Biology, and Genetics to explore genome organization across length and time scales and understand how cells leverage the diverse biophysical properties of chromatin to regulate genome function.
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Gavin Sherlock
Professor of Genetics
Current Research and Scholarly InterestsEvolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species
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Arend Sidow
Professor of Pathology and of Genetics
Current Research and Scholarly InterestsWe have a highly collaborative research program in the evolutionary genomics of cancer. We apply well-established principles of phylogenetics to cancer evolution on the basis of whole genome sequencing and functional genomics data of multiple tumor samples from the same patient. Introductions to our work and the concepts we apply are best found in the Newburger et al paper in Genome Research and the Sidow and Spies review in TIGS.
More information can be found here: http://www.sidowlab.org -
Michael Snyder, Ph.D.
Stanford W. Ascherman Professor of Genetics
Current Research and Scholarly InterestsOur laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states
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Lars Steinmetz
Dieter Schwarz Foundation Endowed Professor
Current Research and Scholarly InterestsThe Steinmetz lab develops genomic technologies to study the genetic basis of complex phenotypes, the mechanisms of gene regulation, and the molecular systems underpinning disease. We’re leveraging biological insights across scales and organisms to predict, diagnose, treat and ultimately prevent disease.
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Vidyani Suryadevara
Instructor, Genetics
Current Research and Scholarly InterestsA Bioengineer by training, she has a breadth of experiences across different scientific disciplines including pulmonary diseases, Alzheimer’s disease, and musculoskeletal disorders, wherein her research projects involved unraveling signaling mechanism behind the disease in order to identify new therapeutic targets and developing imaging modalities for early diagnosis of the disease, thus eventually improving the quality of life in patients. Her current work has been centered around age-associated pathophysiologies like osteoarthritis and Alzheimer's Disease. Her research currently focuses on the clinical translation of a novel noninvasive multimodality imaging approach to detect senescence in osteoarthritis and Alzheimer's Disease and understand the senescence biology in these age-associated diseases.
She has led teams of renowned senescence scientists across the US to develop expert recommendations for biomarkers for senescence. She is also a faculty fellow in the Center for Innovation at Global Health, wherein her focus is to develop region-specific lifestyle interventions to prevent dementia.