School of Medicine
Showing 2,361-2,380 of 4,925 Results
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Mable Lam
Instructor, Neurosurgery
Current Research and Scholarly InterestsMyelin is required for rapid nerve signaling by insulating axons to accelerate action potential propagation. Myelin-forming cells of the central nervous system, called oligodendrocytes, orchestrate one of the most complex morphological transformations in neurobiology. Each oligodendrocyte can extend multiple processes that selectively wrap axons in tens to hundreds of spiraling membrane layers, forming myelin sheaths that vary in thickness and length. Furthermore, oligodendrocytes can respond to neural activity by adding new sheaths or by changing the geometry of pre-existing sheaths to tune neural circuitry, a process known as adaptive myelination.
What are the membrane trafficking mechanisms that drive adaptive myelination in oligodendrocytes?
How can these mechanisms be stimulated to promote myelin regeneration in disease?
By using transgenic mouse models and primary oligodendrocytes, we have found that SNARE-mediated exocytosis drives membrane addition in myelin sheaths. Current research is focused on how these pathways in oligodendrocytes may be regulated during adaptive myelination. -
Vinh Lam
Clinical Assistant Professor, Medicine - Primary Care and Population Health
BioDr. Vinh Lam is a Clinical Assistant Professor in the Department of Medicine, Division of Primary Care and Population health. He earned his MD from the David Geffen School of Medicine at UCLA and chose to stay in Los Angeles to complete his family medicine residency training at UCLA. During his training, Dr. Lam developed a strong interest in teaching and medical education through his involvement with resident education and the graduate medical education committee. He also spent 1 year as a resident informaticist where he also became very interested in informatics, medical technology, and innovative solutions to improving patient health outcomes and decreasing physician burnout. Dr. Lam enjoys caring for patients of all ages from pediatrics to geriatrics, performing office-based procedures, and prioritizing preventative care.
Outside of medicine, Dr. Lam loves to travel with his family, dabbles in photography and videography, and enjoys attempting to recreate meals he has had while traveling with his wife. -
Emmet Lamb
Professor of Gynecology and Obstetrics, Emeritus
BioSee Curriculum Vitae
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Scott R. Lambert, MD
Professor of Ophthalmology and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMy research has focused on improving the visual outcomes of children with congenital cataracts. I organized a randomized clinical trial, the Infant Aphakia Treatment Study to compare the visual outcomes of infants optically corrected with a contact lens vs. an intraocular lens after unilateral cataract surgery. A second area of research has been ocular growth after cataract surgery.
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Lukas D. Landegger
Clinical Instructor, Otolaryngology (Head and Neck Surgery)
BioDr. Landegger is a clinician-scientist (otolaryngologist-head and neck surgeon) and Instructor at Stanford University School of Medicine. After gaining clinical as well as research experience in various countries (US, UK, France, Spain, Germany, Singapore, Australia), he specialized in otology with translational hearing research in Vienna, Austria and for five years in Boston (Mass Eye and Ear, Harvard Medical School), leading to a PhD in Neuroscience. Apart from clinical projects, current basic research foci are funded by a grant obtained from the American Society of Gene & Cell Therapy and include inner ear gene therapy, vestibular schwannoma, noise-induced hearing loss, and others.
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Alfred Lane
Professor of Dermatology and of Pediatrics at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsDeveloping gene therapy for genetic skin diseases is my major focus. Prior to that, we are developing methods to give effective and efficient care to infants with rare and disabling genetic skin diseases including epidermolysis bullosa and ichthyosis as well as infants and children with unusual and difficult to manage vascular malformations. I am also interested in clinical studies within the NICU protecting premature infants skin and clinical studies in children with common skin diseases.
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Barton Lane
Professor of Radiology (Diagnostic Radiology) at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsAs a professor in the Medical Center Line, my primary investigative interest has been in clinical neuroradiology. This encompasses spinal cord and spine disease, degenerative and demyelinating diseases of the central nervous system, strokes and infarction, and chronic epilepsy syndromes. Facial and head and neck vascular malformations and hemangiomas have been a focus of interest for many years, with collaborative projects involving dermatology and functional restoration services.
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Curtis Langlotz
Senior Associate Vice Provost for Research, Professor of Radiology (Integrative Biomedical Imaging Informatics), of Medicine (Biomedical Informatics Research), of Biomedical Data Science and Senior Fellow at the Stanford Institute for HAI
Current Research and Scholarly InterestsMy laboratory develops machine learning methods to help physicians detect disease and eliminate diagnostic errors. My laboratory is developing neural network systems that detect and classify disease on medical images. We also develop natural language processing methods that use the narrative radiology report for contrastive learning and other multi-modal methods that improve the accuracy and capability of machine learning systems.
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Marvin Langston
Assistant Professor of Epidemiology and Population Health
BioDr. Marvin Langston is an Assistant Professor of Epidemiology and Population Health. He is a member of the Stanford Cancer Institute and Urologic Cancer Epidemiology Lab. He is an epidemiologist by training who focuses on the fields of benign prostate and pelvic conditions and urological cancers including prostate and kidney cancers.
Prior to Stanford, he served as a Research Scientist in the Division of Research at Kaiser Permanente Northern California. Dr. Langston received his PhD in Epidemiology from the University of Arizona’s College of Public Health followed by postdoctoral training in Cancer Prevention and Control at Washington University in Saint Louis School of Medicine.
His program of research intends to characterize and measure infectious agents, environmental toxicants, and lifestyle factors; to evaluate the role of these factors in urological cancer etiology and outcomes; and to identify populations at high risk of exposure to these factors. So far he has focused this research to address the following questions: 1) What role do sexually transmitted infections and other systemic infections have in prostate damage and ensuing prostate cancer risk? 2) How can we appropriately model and define early life risk factors for urological cancers? 3) Can we harmonize molecular and clinical aspects of urological condition diagnoses to produce well characterized outcomes for biomarker discovery and etiological investigation? He has primarily addressed these questions using a variety of molecular and clinical epidemiology approaches while developing expertise in the cross-cutting theme of cancer health disparities with particular interests in the cancer care experiences of sexual and gender minorities and racial/ethnic minorities.
Dr. Langston has been studying the impact of exogenous factors on prostate specific antigen (PSA) concentration in young men as a marker of prostate damage and inflammation for over a decade. As early life PSA has been found predictive of future prostate cancer mortality, he has now setout to optimize risk-stratified screening for prostate cancer. This promising approach uses men’s baseline PSA values to inform their risk of future aggressive and/or fatal prostate cancer and determine their frequency of further screening. Under this approach, men with high baseline age-specific total PSA levels receive more frequent screening and men with lower levels receive less frequent screening. Dr. Langston was awarded an R01 from NCI to evaluate this approach using historically collected biospecimen. His funded research trajectory to this point also includes four training awards (2-NCI and 2-NIDDK) and several internal grants. Dr. Langston was selected in the inaugural class of the White House Cancer Moonshot Scholars for his work. -
Benjamin Laniakea
Clinical Associate Professor, Medicine - Primary Care and Population Health
BioDr. Benji Laniakea serves as the chief of the Stanford LGBTQ+ Adult Clinical Program, which offers comprehensive and tailored healthcare for the LGBTQ+ patient population for patients of all ages, sexualities, and gender identities. They also serve as the theme lead for the Sex, Gender, Sexuality, and Sexual Function curriculum at the Stanford School of Medicine for which they received the Arthur L. Bloomfield Award, and have the honor of advising the American Medical Association on LGBTQ+ Health.
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Maarten Lansberg, MD, PhD
Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy research involves the design and conduct of clinical trials to discover new treatments for patients who have suffered a stroke. These trials span treatment of acute stroke, stroke recovery, and stroke prevention. My research in acute stroke is primarily focused on the use of advanced neuroimaging methods (CT and MRI) to select patients who are most likely to benefit from therapies aimed at restoring blood flow to the brain in patients who have suffered a stroke.
