School of Medicine
Showing 541-560 of 5,185 Results
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Anne Brunet
Michele and Timothy Barakett Endowed Professor
Current Research and Scholarly InterestsWe want to understand aging based on the integration of model organisms with diverse lifespans. We have identified pathways involved in delaying aging in response to external stimuli such as availability of nutrients. We are also interested in addressing complex questions about aging in vertebrates, focusing on brain aging and rejuvenation. Finally, we have pioneered the short-lived African killifish as a powerful model to identify new principles of vertebrate aging and ‘suspended animation’.
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Axel Brunger
Professor of Molecular and Cellular Physiology, of Neurology and Neurological Sciences, of Photon Science and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsOne of my primary goals is to elucidate the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, in conjunction with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
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Jennifer L. Bruno
Instructor, Psychiatry and Behavioral Sciences - Interdisciplinary Brain Sciences
Current Research and Scholarly InterestsDr. Bruno is a translational researcher at the interface of developmental cognitive neuropsychology and neurobiology. An overarching goal of her work is to understand developmental windows of vulnerability—periods of risk for falling off the trajectory of typical brain development. Her research utilizes genetics, brain imaging, and deep behavioral phenotyping to bridge computational science with clinical knowledge, translating cutting-edge science to solve problems of great clinical need.
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Douglas L. Brutlag
Professor of Biochemistry, Emeritus
Current Research and Scholarly InterestsMy primary interest is to understand the flow of information from the genome to the phenotype of an organism. This interest includes predicting the structure and function of genes and proteins from their primary sequence, predicting function from structure simulating protein folding and ligand docking, and predicitng disease from genome variations. These goals are the same as the goals of molecular biology, however, we use primarily computational approaches.
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Zev Bryant
Associate Professor of Bioengineering and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsMolecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work.
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Vivek P. Buch, MD
Assistant Professor of Neurosurgery and, by courtesy, of Bioengineering
BioDr. Buch is a board certified neurosurgeon with fellowship training in pediatric and adult epilepsy, functional, and minimally invasive neurosurgery. He is an Assistant Professor of Neurosurgery and Bioengineering, and the Christina and Hamid Moghadam Endowed Faculty Scholar at Stanford University.
Dr. Buch focuses his expertise on the open and minimally invasive treatment of epilepsy, low grade brain tumors, movement and neuropsychiatric disorders, facial and body pain syndromes, and other complex neurological conditions. He uses advanced and innovative techniques to treat both pediatric and adult patients. For each patient, he develops a personalized care plan that is designed to be both comprehensive and compassionate.
Dr. Buch has conducted extensive research. His academic career goal is to develop restorative bioengineering approaches for complex neurocognitive, neurodevelopmental, and neuropsychiatric disorders. He is creating network-neuroprosthetics and precision molecular therapies to restore abnormal brain circuit function in these vulnerable patient populations. He is further pioneering novel intraoperative technologies including personalized network-based targeting, holographic mixed reality, and artificial intelligence platforms for minimally invasive cranial surgery. He has presented this work at numerous professional conferences at the national and international level.
He has co-authored articles on his research discoveries in Science, Nature, Nature Medicine, Nature Neuroscience, Nature Communications, Neuron, Brain, Annals of Surgery, New England Journal of Medicine, ACS Nano, and many other journals. Articles focus on developing novel network control theory applications to human brain functions and new techniques and technologies to enhance neurosurgical effectiveness and patient outcomes.
He is the AI/Data Science Section Editor for NEUROSURGERY, and a guest editor for Surgical Innovation and Brain Sciences. He also has co-authored chapters in the books Neurosurgical Atlas, Operative Techniques in Epilepsy Surgery, Deep Brain Stimulation, and The Encyclopedia of Medical Robotics.
For his clinical, research, and academic achievements. Dr. Buch has earned many honors. He has won awards from the American Association of Neurological Surgeons, American Roentgen Ray Society, Congress of Neurological Surgeons, and National Institutes of Health, including twice earning the honor of national Young Neurosurgeon award from the Congress of Neurological Surgeons in his first 5 years of practice.
Dr. Buch is a national leader in epilepsy surgery, functional neurosurgery, and surgical AI. He is a member of the Wu Tsai Neuroscience Institute, Human Performance Alliance, Stanford BioX, and Human Centered AI Institute. He is also a member of the American Association of Neurological Surgeons, Congress of Neurological Surgeons, World Society for Stereotactic and Functional Neurosurgery, American Association of Stereotactic and Functional Neurosurgery, American Epeilepsy Soeciety, and Alpha Omega Alpha Medical Honor Society.
He has designed and holds patents on artificial intelligence systems for surgical guidance, neural control signals for closed-loop stimulation therapy, novel arrays for bioelectrical sensing and stimulation, and surgical devices including percutaneous anchoring mechanisms and digital neurological assessment tools.
Essential tremor patient story: https://www.youtube.com/watch?v=fV6BzyU9b3c
Parkinson's disease patient story: https://www.youtube.com/watch?v=vAKP7SRKs08
Epilepsy patient story: https://www.youtube.com/watch?v=HXy-gXg0t94&t=3s
Deep brain stimulation treatment: https://www.youtube.com/watch?v=xLgEcb447gA&t=1s
Laser interstitial thermal therapy treatment: https://www.youtube.com/watch?v=z-nRUMbs2kY&t=2s
MR-guided focused ultrasound treatment: https://www.youtube.com/watch?v=3Bwq2YxD9eU -
Paul Buckmaster, DVM, PhD
Professor of Comparative Medicine and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsMechanisms of epilepsy, especially temporal lobe epilepsy.
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Marion S. Buckwalter, MD, PhD
Professor of Neurology and Neurological Sciences (Adult Neurology) and of Neurosurgery
Current Research and Scholarly InterestsThe goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic and clinical research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how they affect short-term brain injury and long term outcomes like dementia and depression.
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Sujatha Buddhe
Clinical Professor, Pediatrics - Cardiology
Clinical Associate Professor (By courtesy), Radiology - Pediatric RadiologyBioDr. Buddhe earned her medical degree from the Osmania Medical College, Hyderabad, India. She completed her pediatrics residency and chief residency at the Brookdale University Hospital and Medical Center, NY and pediatric cardiology fellowship at the Children's Hospital of Michigan. Her advanced fellowship training in pediatric cardiac non-invasive imaging was completed at the Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital in New York. She earned her Masters degree in Clinical research and statistical analysis at the University of Michigan, Ann Arbor. She worked at Seattle Children's Hospital, University of Washington for almost ten years where she served as the Director of Non-invasive Imaging research and the Co-Director of cardiac MRI program. Her research interests include echocardiography and Cardiac MRI.
