School of Medicine
Showing 3,391-3,400 of 4,928 Results
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Adolf Pfefferbaum
Professor of Psychiatry and Behavioral Sciences, Emeritus
Current Research and Scholarly InterestsDevelopment and application of magnetic resonance imaging approaches for in vivo studies of human and animal brain integrity in neurodegenerative conditions, including alcoholism, HIV infection, Alzheimer's disease, and normal aging
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Anuradha Phadke
Clinical Associate Professor, Medicine - Primary Care and Population Health
BioDr. Phadke is a board-certified primary care internal medicine physician and Clinical Associate Professor of Primary Care & Population Health at the Stanford School of Medicine. She holds several administrative roles including Associate Physician Improvement Leader for the Stanford Department of Medicine, Associate Chief Quality Officer for Ambulatory Care and Population Health at Stanford Healthcare, and co-chair of the Quality Improvement Subcommittee for the Society for General Internal Medicine.
In her clinical care, she enjoys forming deep and lasting relationships with patients. She seeks to listen actively and provide patients with guidance and support as they work toward their health goals. Her clinical expertise is in chronic disease management and preventive care.
She teaches clinical primary care to internal medicine residents and medical students. She actively mentors student and resident quality improvement projects.
Her scholarly focus is ambulatory quality improvement evaluation. She has published and presented on a wide array of topics including workforce QI engagement, quality improvement evaluation of primary care improvement initiatives, hypertension management, and quality improvement to narrow health disparities. She enjoys working with trainees and students on scholarship. -
Edward A. Pham
Instructor, Medicine - Gastroenterology & Hepatology
BioMy interest in medicine and research was triggered by my mother’s battle with chronic hepatitis C, which made me realize the transformational power of biomedical research in treating patients. Therefore, my career goal is to become a physician scientist in the field of gastroenterology and hepatology dedicated to translating discoveries in the laboratory into novel medical treatment modalities. My research focus is alterations in phosphoinositides signaling and its pathogenesis in cancers of the hepatobiliary and luminal GI tract with the goal to identify novel targets for therapeutic intervention. I also have a particular interest in understanding the interface between chronic viral infection and cancer through studying how the innate and adaptive immune system are perturbed in chronic viral infections
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Tho Duc Pham
Clinical Associate Professor, Pathology
Current Research and Scholarly InterestsMy areas of interest involve exploring antibody function as it relates to transfusion medicine, blood safety, and emerging infectious diseases. This ranges from natural immune responses to the ABO blood group, antibody profiling anti-SARS-CoV-2 antibodies, and studying HEV seroprevalence in the local community. I am also interested in exploring statistical approaches to improve blood product availability and overall health care efficiency in a tertiary care system.
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Trung Hoang Minh Pham
Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsUncovering mechanisms of tissue immunity and immunophysiology during persistent infection
The immune system safeguards the health of complex organisms by rapidly eliminating invading pathogens, curbing infection-induced tissue disruptions, and maintaining tissue homeostasis. Many bacterial pathogens evade host antimicrobial mechanisms and persist in infected tissues at low levels for long periods of time even in the presence of innate and adaptive immune resistance. During persistent infection, the immune system simultaneously orchestrates antimicrobial responses to contain the pathogen, repairs damaged tissue, regulates nutrient resources, and maintains other tissue physiological functions to ensure host survival. Failure of any of these tasks leads to uncontrolled infection, devastating disease, and even death. The goals of our research are to understand:
1)What are the innate and adaptive immune cellular mechanisms that contain pathogens during persistent infection?
2)How are tissue physiological functions, such as tissue repair and nutrient regulation, maintained during persistent infection?
3)How do pathogens survive innate and adaptive antimicrobial mechanisms in infected tissues?
4)How does persistent infection impact host immunity to secondary infections of a similar or different pathogen?
Through investigating these fundamental questions, we may be able to decode the underlying cellular and molecular mechanisms that can be harnessed to eradicate infections, promote tissue resilience, and restore health after an infectious insult. We employ animal infection models and bring together immunology, tissue biology, microbiology, and genetics to uncover the mechanisms of tissue immunity and immunophysiology during persistent infection from the molecular to organismal level.
Current areas of research:
•Development, maintenance, and plasticity of macrophage functional diversity in infected tissue
•Tissue repair and nutrient regulation during persistent infection
•Cellular dynamics and bacterial persistence in lymphoid organs
