School of Medicine
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Vedant Pargaonkar
Basic Life Research Scientist, Medicine - Med/Cardiovascular Medicine
BioMy long-term research interests involve development of algorithms using computational methods for early detection of coronary pathophysiology including, endothelial dysfunction and microvascular dysfunction (MVD) and/or a myocardial bridge (MB) in patients with angina and no obstructive coronary artery disease (NOCAD) and the identification of novel target therapies for primary prevention and improved prognosis in these patients. Under the mentorship of Dr. Jennifer Tremmel in Cardiovascular medicine at Stanford, I have been systematically studying to better understand the underlying pathophysiology of these patients, as well as the optimal use of diagnostic testing and treatment using the angina and no-obstructive CAD Registry at Stanford. In collaboration with other investigators in this field, we have published multiple scientific articles highlighting the limitations of current testing in this population and identification of novel diagnostic tools for early diagnosis and management of patients with angina and no obstructive CAD. My research also focuses on myocardial infarction (MI) in women, particularly spontaneous coronary artery dissection (SCAD). I have been involved in the design and execution of the first international collaborative study in SCAD, investigating peripartum vs. non-peripartum SCAD. This is analyzing the largest cohort of patients recruited from multiple US and non-US sites to understand the pathophysiological differences in these patient cohorts.
