School of Medicine
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Paul George, MD, PhD
Assistant Professor of Neurology and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsCONDUCTIVE POLYMER SCAFFOLDS FOR STEM CELL-ENHANCED STROKE RECOVERY:
We focus on developing conductive polymers for stem cell applications. We have created a microfabricated, polymeric system that can continuously interact with its biological environment. This interactive polymer platform allows modifications of the recovery environment to determine essential repair mechanisms. Recent work studies the effect of electrical stimulation on neural stem cells seeded on the conductive scaffold and the pathways by which it enhances stroke recovery Further understanding the combined effect of electrical stimulation and stem cells in augmenting neural repair for clinical translational is a major focus of this research going forward.
BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for stroke and neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration and stroke recovery. Recent work utilizing these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.
APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes. -
Carl Gold
Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Associate Professor (By courtesy), NeurosurgeryBioDr. Gold is a board-certified neurologist who is fellowship-trained in the diagnosis and treatment of neurological disorders in hospitalized patients. He cares for a broad range of patients, including individuals with seizures, central nervous system infections, autoimmune diseases, headaches, neuromuscular conditions, and neurological complications of cancer. Dr. Gold's primary research interest focuses on enhancing the communication skills of neurology residents, and he serves as the Director of the Stanford Neurology Residency Communication Coaching Program. He is also the Fellowship Director of the Stanford Neurohospitalist Fellowship.
Dr. Gold serves as Vice Chair of Quality, Safety, & Experience for the Department of Neurology & Neurological Sciences. In this role, he coordinates projects aimed at improving care for patients with neurological conditions across the health system.
For more information on the Stanford Neurohospitalist Program & Fellowship, please visit: https://med.stanford.edu/neurology/divisions/neurohospitalist.html
Learn more about the Stanford Neurology Communication Coaching Program by visiting: http://med.stanford.edu/neurology/education/resident-coaching.html
Additional information on Stanford Neurology's efforts in Quality, Safety, & Value can be found here: http://med.stanford.edu/neurology/quality.html -
Olga Fedin Goldberg
Clinical Associate Professor, Neurology & Neurological Sciences
BioDr. Goldberg is board-certified in Neurology by the American Board of Psychiatry and Neurology. She provides comprehensive neurologic care to patients with a broad range of neurologic conditions, including those who have multiple neurologic conditions. She is interested in medical education for neurology residents and for referring primary care providers and serves as Director of Neurology Resident Continuity Clinic. Additionally, she completed the Stanford CELT (Clinical Education Leadership Training) Program for developing skills in quality improvement. She has led or played a key role in multiple quality improvement projects in the Department of Neurology, including those focused on increasing patient understanding of their neurologic medications upon hospital discharge, improvement of outcomes for headache patients seen in primary care, and in optimizing clinic processes involved in collection of cerebrospinal fluid.
