School of Medicine
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Matthew Landry
Postdoctoral Scholar, SCRDP/ Heart Disease Prevention
BioCurrent research focuses on identifying the optimal diet (or diets) for chronic disease prevention and addressing the challenges of designing, implementing and reporting clinical trials that test dietary patterns. Particularly interested behavioral interventions that promote plant-forward and plant-based diets. Passionate advocator for policies that address nutrition-related health inequalities particularly in low resource settings and/or with communities experiencing health inequalities related to food insecurity and structural disparities.
*Currently on the Job Market for Assistant Professor Positions starting Fall 2023* -
Yuan-Hung Lo
Postdoctoral Scholar, Hematology
BioI am currently working on several projects to understand the control of gastrointestinal and cancer stem cell biology, especially how critical intrinsic genetic mutations and extrinsic extracellular components within the microenvironment influence cell behaviors. Stem cells of the gastrointestinal tract give rise to the surface lining of the epithelium, and must continuously produce new cells to replace those shed into the lumen throughout the lifespan. When mutations accumulate in these stem cells, they can grow uncontrollably into benign polyps or malignant tumors. In Dr. Calvin Kuo’s laboratory, I have used transgenic mice and primary human organoids as the models. Human organoids provide a robust primary culture system to recapitulate 3D structure and multilineage differentiation, which represents an underutilized method for the study of stem cell and cancer biology (Lo et al, Nature Cancer 2020). I have focused my efforts on establishing next generation CRISPR/Cas9 genome editing tools in primary human organoids, and applying this powerful system to gain insight into how different signaling pathways can contribute to gastrointestinal stem cell activity and tumorigenesis (Lo et al, Cancer Discovery 2021).
