School of Medicine
Showing 1-37 of 37 Results
Professor of Medicine (Nephrology)
Current Research and Scholarly InterestsWe are continuing to grow a glomerulonephritis cohort study, including immunologic characterization. We have completed interventional studies of preeclampsia exploring the nitric oxide, endothelin system and effects on glomerular function and morphometry. We continue to recruit patients for treatment and observational studies of glomerular disease, including FSGS, membranous and particularly IgA nephropathy. We also are actively studying renal disease in systemic amyloidosis.
Philip W. Lavori
Professor of Biomedical Data Science, Emeritus
Current Research and Scholarly InterestsBiostatistics, clinical trials, longitudinal studies, casual inference from observational studies, genetic tissue banking, informed consent. Trial designs for dynamic (adaptive) treatment regimes, psychiatric research, cancer.
Laura C. Lazzeroni, Ph.D.
Professor (Research) of Psychiatry and Behavioral Sciences and of Biomedical Data Science
Current Research and Scholarly InterestsStatistics/Data Science. I develop & apply models, methods & algorithms for complex data in medical science & biology. I am also interested in the interplay between fundamental statistical properties (e.g. variability, bias, p-values) & how scientists actually use & interpret data. My work in statistical genetics includes: the invention of Plaid bi-clustering for gene expression data; methods for twin, association, & family studies; multiple testing & estimation for high dimensional arrays.
Assistant Professor of Cardiothoracic Surgery (Adult Cardiac Surgery)
BioDr. Anson Lee specializes in the surgical treatment of all heart diseases, including ischemic heart disease, structural heart disease, aortic disease, and arrhythmias. He has practiced cardiothoracic surgery at Stanford since 2015. Dr. Lee has a special interest in the surgical treatment of abnormal heart rhythms and minimally invasive techniques to treat heart disease.
David Lee, MD
Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly Interests1. Novel treatments and devices for the treatment of valvular disease
2. Alcohol septal ablation for hypertrophic obstructive cardiomyopathy
3. Novel approaches to coronary revascularization
4. Closure devices for atrial septal defects and patent foramen ovale
5. Novel treatments for hypertension
Jason T. Lee, MD
Professor of Surgery (Vascular Surgery)
Current Research and Scholarly InterestsDr. Lee is the Principal Investigator on several clinical trials examining therapeutic strategies for management of complex aortic aneurysm disease as well as aortic dissection.
Dr. Lees clinical interests include:
Endovascular repair of abdominal/thoracic aneurysms and dissections
Fenestrated and Branch Repair of the thoracic, thoracoabdominal, and abdominal aneurysms
Thoracic outlet syndrome
Vascular disorders in high-performance athletes
Associate Professor of Medicine (Endocrinology) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsI am a clinical scientist (PhD epidemiology), endocrinologist, and CMO at VAPA Cooperative Studies Program Coordinating Center . My group does pattern and prediction mapping along the life-course of interventions/outcomes and how healthcare system can positively impact health longitudinally. We use novel molecular epi, 'big' data like EHRs with advanced new designs/methods/technologies. These interests cut across multiple complex chronic diseases, aging, & critical lifespan stages.
So Ah Lee
Postdoctoral Scholar, Cardiovascular Institute
BioSoah is a biomaterials scientist and bio engineer who specializes in developing artificial cell niche using hydrogels for various tissue engineering/drug delivery applications.
During 5 years of Ph.D. training in Stem Cell and Biomaterials Laboratory under Dr. Fan Yang's guidance, Soah has focused on developing novel hydrogel-based cell niche platforms and examining effect of biophysical properties of the cell niche using various natural polymers (Matrigel, collagen, alginate, etc.) and synthetic polymers (poly(ethylene glycol), poly(acryl amide) etc.).
After completion of her Ph.D. training, she has joined Sean Wu's lab in CVI to extend her expertise in biomaterials to develop a bioink for bioprinting 3D cardiac tissues.
Maureen Lyles D'Ambrogio Professor in the School of Medicine
Current Research and Scholarly InterestsOur long term interest is to have a better understanding of the natural antithrombotic pathways and the pathophysiology of vascular thrombosis. We have focused on thrombin, the key enzyme in the blood clotting cascade.Our goal is to develop new antithrombotic agents and devise new diagnostic tests for vascular thrombotic disorders.
Associate Professor of Mechanical Engineering and, by courtesy, of Radiology (Radiological Sciences Laboratory)
Current Research and Scholarly InterestsMy lab's research involves the function, degeneration and repair of musculoskeletal soft tissues, with a focus on meniscal fibrocartilage and articular cartilage. We are particularly interested in the complex interactions between biophysical and biochemical cues in controlling cell behavior, the roles of these interactions in degenerative conditions such as osteoarthritis, and development of tissue engineered 3D model systems for studying physical influences on primary and progenitor cells.
Professor of Radiology (Molecular Imaging Program at Stanford/Nuclear Medicine) and, by courtesy, of Physics, of Electrical Engineering and of BioengineeringOn Partial Leave from 09/01/2021 To 08/31/2022
Current Research and Scholarly InterestsMolecular Imaging Instrumentation
Our research interests involve the development of novel instrumentation and software algorithms for in vivo imaging of cellular and molecular signatures of disease in humans and small laboratory animal subjects.
Eldrin F. Lewis, MD, MPH
Simon H. Stertzer, MD, Professor
BioDr. Lewis is a board-certified, fellowship-trained specialist in cardiovascular medicine. He is the chief of the Division of Cardiovascular Medicine and a professor of cardiovascular medicine.
Dr. Lewis is an esteemed clinician-scientist who specializes in the care of patients with advanced heart failure. He is an internationally recognized expert on heart failure, heart transplant, and quality of life for heart failure patients. He cares deeply about his patients as well as his colleagues, the hospital, and the School of Medicine. Dr. Lewis is committed to diversity and inclusion, as well as expanding Stanford clinical research initiatives.
A fundamental principle of Dr. Lewis’ practice is his belief that “there is more to life than death,” that cardiovascular care should go beyond helping patients survive to also helping them enjoy the best possible quality of life.
Dr. Lewis has deep expertise in conducting clinical trials examining diagnostic and therapeutic approaches to heart failure. He has done innovative work to create systems for incorporating quality of life measures for cardiovascular patients into electronic health records. This research has received support from the National Heart, Lung and Blood Institute and the National Institutes of Health.
Much of his quality of life research has focused on patient-reported outcomes. Dr. Lewis emphasizes the importance of looking at how a disease, whether chronic or acute, impacts people’s ability to function and perform their activities of daily living. Strategies to improve patients’ well-being focus not only on their physical symptoms but also on depression, anxiety, exercise capacity, and ability to function in daily living.
Dr. Lewis’ commitment to expanding clinical research initiatives will give patients more opportunities to participate in the clinical trials and access the latest care strategies that can translate into better outcomes. The goal is early access to the most advanced technology, pharmacology, and device therapy that can change outcomes for the better. He also envisions forming closer partnerships with community cardiologists and capitalizing further on Stanford’s proximity to and unique relationships with the digital technology leaders of Silicon Valley to enhance the use of digital technology for monitoring patients, optimizing treatment, and tracking outcomes.
He has authored nearly 200 articles published in peer-reviewed journals including the New England Journal of Medicine, Journal of the American College of Cardiology, Circulation, JAMA Cardiology, JAMA Internal Medicine, and many more. He is also on multiple editorial boards for cardiovascular journals and was an associate editor for Circulation–Heart Failure. In addition, he is an author of professional society clinical practice guidelines and scientific statements from both the American Heart Association (AHA) and the Food and Drug Administration.
Dr. Lewis’ honors for clinical care, scholarship, and research include the Joel Gordon Miller Award for community service and leadership from the University of Pennsylvania School of Medicine. He also was one of the first recipients of the Minority Faculty Development Award, which recognizes the research potential of young physicians. Dr. Lewis has received a grant from the Robert Wood Johnson Foundation to study the role of quality of life assessment in clinical decision making in patients with heart failure.
He is a fellow of the American College of Cardiology and the National American Heart Association (AHA) Research Committee. In addition, Dr. Lewis was as a member of the AHA Founders Affiliate Board of Directors, chair of the Council on Clinical Cardiology, and research chair of the Association of Black Cardiologists. He also serves on scientific committees to review grants for the AHA and on the FDA Task Force for the Standardization of Definitions for Endpoint Events in Cardiovascular Trials.
Jin Billy Li
Associate Professor of Genetics
Current Research and Scholarly InterestsThe Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.
David Liang, MD, PhD
Professor of Medicine (Cardiovascular) at the Stanford University Medical Center, Emeritus
BioStanford researchers are creating a micro-device that physicians could guide through the body to help diagnose and treat clogged arteries and other diseases. Tethered to the outside world by a thin wire, a tiny machine creeps through blood vessels, searching out deadly plaques and obliterating them with a zap of a laser. While a laser will come later, for now David Liang, MD, PhD, is focusing on a tiny eye that could give physicians an unprecedented view into blood vessels.
Professor of Medicine (Cardiovascular Medicine)
BioDr. Liao is a Professor of Medicine and co-Director of Stanford Cardiac Amyloid Center. The major goal of her research program focuses on understanding the mechanisms that underlie the pathophysiology of heart failure and developing novel treatments to combat this process. Her laboratory has played an international leading role in the study of amyloid light chain (AL) cardiomyopathy, a rare and fatal form of cardiovascular disease. We have described the underlying pathophysiologic basis for amyloid cardiomyopathy and found that the circulating amyloidogenic light chain proteins that characterize this disease directly result in a specific cardiotoxic response. Consequently, our research work has redefined AL cardiomyopathy and has raised new treatment approaches. More recently, her research efforts have expanded to include transthyretin (ATTR) cardiac amyloidosis.
In line with her goal of revealing novel therapeutic strategies for patients with cardiovascular disease, our efforts have also focused on characterizing and harnessing endogenous cardiac regenerative mechanisms. Her laboratory initially demonstrated the therapeutic potential of exogenous primitive muscle cells delivered to the injured heart. This work was among the earliest milestones in the field and served as the basis for an international trial of cell-based therapy. Subsequently, Liao lab identified and characterized a population of cardiac progenitor cells and its relationship and dynamic activity following cardiac injury in the adult heart. Her laboratory aims to reveal the molecular mechanisms regulating the endogenous regenerative capacity of the heart and to harness such repair mechanisms for the treatment of cardiovascular disease. Dr. Liao has lectured extensively on both amyloid cardiomyopathy and stem cell biology, and have maintained a history of independent NIH funding in these areas for more than two decades.
Over the course of her academic career, she has taken the greatest pride in mentoring the next generation of scientists. Dr. Liao has had the privilege to supervise several dozen students, postdoctoral fellows, and junior faculty, many of whom have gone on to independent academic careers at the highest institutions. Her contribution to the advancement of scientific knowledge also includes lecturing at various university and academic institutions as well as at scores of conferences and symposia locally, nationally, and internationally.
Associate Professor of Medicine (Hematology)
Current Research and Scholarly Interests1) Design of phase I/II trials for the treatment of Multiple Myeloma and Amyloidosis
2) Conduct of clinical trials to improve the treatment of patients with acute lymphoblastic leukemia (ALL)
3) Outcomes research using clinical databases for patients with Multiple Myeloma and Amyloidosis
4) Characterization of the molecular mechanism of MLL-induced acute leukemia
Clinical Associate Professor, Medicine - Primary Care and Population Health
Current Research and Scholarly Interests-Digital Health
-Medical device design, prototyping, testing and clinical trials
-Behavioral determinants of chronic disease
-Novel diagnostic processes for medical mysteries
-Medical Humanities and Arts
Assistant Professor (Research) of Surgery (Pediatric Surgery)
• Big data analytics for quality improvement and clinical effectiveness
• Disease biomarker discovery through multi-omics based analyses
• Assistant Professor Surgery
• B.S., Biochemistry, Fudan University, China (1990)
• M.A., Molecular and Developmental Biology, UCLA, US (1994)
• Ph.D., Biological Chemistry, UCLA, US (1996)
• Postdoctoral training, medicine/oncology/Computer science, Stanford University, US (1996-1998)
• Business administration, Leavey School of Business, Santa Clara University, US (2000-2001)
Juliana Liu, MSN, RN, ANP-C
Affiliate, CVI/Vera Moulton Wall Center
BioJuliana Liu, MSN, RN, ANP-C is the Program Manager and Nurse Practitioner for the Adult Pulmonary Hypertension Service at Stanford. She received her Adult Nurse Practitioner (ANP) degree from the University of California, San Francisco School of Nursing. She has a BA in History from Pomona College. Juliana Liu has worked in the Pulmonary Hypertension field since 2002, and has presented at numerous nursing and patient conferences in the US and abroad. She has also served as member and chair on several committees of the Pulmonary Hypertension Association.
Assistant Professor of Developmental Biology (Stem Cell)
Current Research and Scholarly InterestsWe have developed a strategy to generate fairly pure populations of various human tissue progenitors in a dish from embryonic stem cells (ESCs). We have delineated the sequential lineage steps through which ESCs diversify into various tissues, and in so doing, developed methods to exclusively induce certain fates at the expense of others. The resultant pure populations of tissue progenitors are the fundamental building blocks for regenerative medicine.
Jonathan Z. Long
Assistant Professor of Pathology
Current Research and Scholarly InterestsOur laboratory focuses on the endocrine hormones and other circulating hormone-like molecules that regulate mammalian energy metabolism. With modern mass spectrometry, it is now recognized that blood plasma likely contains many more bioactive factors than previously recognized, secreted by cell types that were not previously considered to have endocrine functions. What are the identities of these molecules? What energy stressors do they respond to? Where are they made? What cell types or tissues do they act on? We use chemical biology and mass spectrometry-based technologies as discovery tools. We combine these tools with classical biochemical and genetic approaches in cell and animal models. Our goal is to uncover new endocrine pathways of organismal energy metabolism. Recent studies from our laboratory have identified a family of cold-regulated circulating lipids that stimulate mitochondrial respiration as well as an exercise-stimulated thermogenic polypeptide hormone. We suspect that many more remain to be discovered. We anticipate that our approach will uncover fundamental mechanisms that control mammalian energy homeostasis. In the long term, we hope to translate our discoveries into therapeutic opportunities that matter for metabolic and other age-associated chronic diseases.
Deane P. and Louise Mitchell Professor in the School of Medicine and Professor, by courtesy, of Materials Science and EngineeringOn Partial Leave from 08/02/2021 To 11/30/2021
Current Research and Scholarly InterestsWe have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2) Distraction Osteogenesis, 3) Fibroblast heterogeneity and fibrosis repair, 4) Scarless Fetal Wound Healing, 5) Skeletal Stem Cells, 6) Novel Gene and Stem Cell Therapeutic Approaches.
Clinical Associate Professor, Medicine - Cardiovascular Medicine
Current Research and Scholarly InterestsAdult Congenital Heart Disease