School of Medicine
Showing 1-50 of 153 Results
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Daibhid O Maoileidigh
Assistant Professor of Otolaryngology-Head and Neck Surgery
Current Research and Scholarly InterestsThe Ó Maoiléidigh group employs mathematical and computational approaches to better understand normal hearing and hearing impairment. Because complete restoration of auditory function by artificial devices or regenerative treatments will only be possible when experiments and computational modeling align, we work closely with experimental laboratories. Our goal is to understand contemporary experimental observations, to make experimentally testable predictions, and to motivate new experiments. We are pursuing several projects.
Hair-Bundle Mechanics
Auditory and balance organs rely on hair cells to convert mechanical vibrations into electrical signals for transmission to the brain. In response to the quietest sounds we can hear, the hair cell's mechanical sensor, the hair bundle, moves by less than one-billionth of a meter. To determine how this astounding sensitivity is possible, we construct computational models of hair-bundle mechanics. By comparing models with experimental observations, we are learning how a hair bundle's geometry, material properties, and ability to move spontaneously determine its function.
Cochlear Mechanics
The cochlea contains the auditory organ that houses the sensory hair cells in mammals. Vibrations in the cochlea arising from sound are amplified more than a thousandfold by the ear's active process. New experimental techniques have additionally revealed that the cochlea vibrates in a complex manner in response to sound. We use computational models to interpret these observations and to make hypotheses about how the cochlea works. -
Lucy Erin O'Brien
Assistant Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsMany adult organs tune their functional capacity to variable levels of physiologic demand. Adaptive organ resizing breaks the allometry of the body plan that was established during development, suggesting that it occurs through different mechanisms. Emerging evidence points to stem cells as key players in these mechanisms. We use the Drosophila midgut, a stem-cell based organ analogous to the vertebrate small intestine, as a simple model to uncover the rules that govern adaptive remodeling.
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Hugh O'Brodovich
Arline and Pete Harman Professor for the Chair in the Department of Pediatrics in the School of Medicine, Emeritus
Current Research and Scholarly InterestsClinical:
Pulmonary edema, acute respiratory distress syndromes (ARDS), hyaline membrane disease (HMD), bronchopulmonary dysplasia (BPD)
Basic Science:
Lung epithelial sodium transport
Genetic influences on the development of BPD -
Ruth O'hara
Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
Current Research and Scholarly InterestsDr. O'Hara's research aims to investigate how cognitive information processing deficits subserve affective symptoms in psychiatric disorders, and interact with key brain networks integral to these disorders. To do so, she has implemented a translational, interdisciplinary program that encompasses cellular models, brain and behavioral assays of affective and cognitive information processing systems in psychiatric disorders across the lifespan.
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Jack O'Sullivan
Postdoctoral Research Fellow, Cardiovascular Medicine
BioI am an Australian physician (MD, PhD) currently working as a Post-Doctoral Research Fellow at Stanford University. I am jointly supervised by Professor Euan Ashley and Professor John Ioannidis and am an active member of both labs: the Ashley Lab and Meta-Research Innovation Center at Stanford (METRICS, Ioannidis).
My fellowship concerns the diagnosis and risk prediction of cardiovascular disease. I employ a variety of statistical methods to assess new diagnostic technologies, such as smart phones and smart wearables, and my work also extends to computational cardiac genetics. The data sources I utilize to conduct my research are numerous, but include large datasets such as the UK Biobank, as well as publicly available dataset (meta-analysis and meta-research). I have also previously used large electronic health records (>250 million EHRs).
Aside from my own research prioritizes (above), I also work on studies conducted collaboratively within the Ashley Lab, the Division of Cardiovascular Medicine and METRICS. These studies broadly include digital health randomized controlled trials (RCTs) and meta-research (including statistical methods such as meta-analysis, meta-regression etc).
I previously completed a DPhil (PhD) in clinical epidemiology at the University of Oxford as a Clarendon Scholar. The title of My DPhil thesis was: “Biostatistical and meta-research approaches to assess diagnostic tests”. My published research is available at my google scholar page (https://scholar.google.co.uk/citations?user=n5l7tL8AAAAJ&hl=en) and some of my code is publicly available at my GitHub (https://github.com/jackosullivanoxford).
Beyond academic institutions, I also consult to the World Health Organization (WHO); including on WHO guidelines, where I am currently the methodological chair for a WHO guideline concerning the early(ier) detection of disease in adults. I also work as an associate editor at one of the BMJ sub-journals: BMJ EBM. During my DPhil I worked clinically at Oxford University Hospitals (John Radcliffe Hospital) and intend to return to clinical practice as a Physician-Scientist at Stanford upon the completion of my research Fellowship.
You can follow me on twitter (https://twitter.com/DrJackOSullivan): where you will find me tweeting about statistics, surfing, cardiology, medicine, epidemiology, health policy, and, occasionally, politics. -
David Oakes
Professor of Surgery at the Santa Clara Valley Medical Center, Emeritus
Current Research and Scholarly InterestsTrauma, especially splenic and thoracic
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Detlef Obal
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsI am primarily working at the Cardiovascular Institute (Director Joseph Wu, MD, PhD), studying the effect of different anesthetics on human induced pluripotent stem cells (hiPSC). Considering the current opioid epidemic, I am currently focusing on the effect of chronic opioid exposure on endothelial and cardiac function.
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Juno Obedin-Maliver
Assistant Professor of Obstetrics and Gynecology
BioJuno Obedin-Maliver, MD, MPH, MAS, FACOG, is an Assistant Professor in the Department of Obstetrics and Gynecology at Stanford University School of Medicine.
Dr. Juno Obedin-Maliver is a board-certified obstetrician/gynecologist who provides excellent clinical care and strives to advance scientific knowledge through her research.
She practices full-spectrum gynecology including outpatient, in-patient, operative, and emergency care services. This specifically includes collaborative management of cervical dysplasia and abnormal pap smears, abnormal uterine bleeding, contraception and family planning, pelvic pain, abnormal discharge, sexually transmitted infection testing and treatment, and more. She specializes in the gynecological and reproductive health care needs of sexual and gender minority people which include but are not limited to lesbian, gay, bisexual, transgender, queer and questioning (LGBTQ+) people. This interest and experience drives her research interests towards promoting the health and well-being and equity of LGBTQ people.
Dr. Obedin-Maliver, is the Co-Director of The PRIDE Study (pridestudy.org), a multi-site online prospective longitudinal cohort of sexual and gender minority individuals based at Stanford. She also serves on the medical advisory board of the University of California San Francisco Center of Excellence for Transgender Health and is helping to author the next version of the World Professional Association for Transgender Health (WPATH) Standards of Care. Dr. Obedin-Maliver has also been active in health policy including involvement in helping to legally redefine consideration of sexually intimate partner status and to remove the Medicare Non-Coverage Determination ruling on gender -affirming surgeries. -
Michelle Odden
Associate Professor of Health Research and Policy (Epidemiology)
BioMichelle Odden, PhD, is an Associate Professor of Epidemiology in the Department of Health Research and Policy. Her research aims to improve our understanding of the optimal preventive strategies for chronic disease in older adults, particularly those who have been underrepresented in research including the very old, frail, and racial/ethnic minorities. Her work has focused on prevention of cardiovascular and kidney outcomes, as well as preservation of physical and cognitive function in older adults. She is also strongly interested in epidemiological and statistical methods to reduce biases in observational studies. Dr. Odden came to Stanford from Oregon State University, where she helped build the new College of Public Health and Human Sciences. She completed her Ph.D. in Epidemiology from the University of California, Berkeley (2009), a postdoctoral fellowship at the University of California, San Francisco in Primary Care Research (2011).
