School of Medicine


Showing 11-20 of 74 Results

  • Sneha Ramakrishna

    Sneha Ramakrishna

    Assistant Professor of Pediatrics (Hematology/Oncology)

    BioSneha Ramakrishna obtained her B. A. from the University of Chicago and her M.D. from the Cleveland Clinic Lerner College of Medicine at Case Western Reserve University. In medical school, through the Howard Hughes Medical Research Scholar Award, she joined Dr. Crystal Mackall’s laboratory, where she designed and developed various GD2 CAR-Ts and tested them in preclinical models. During her residency training in Pediatrics at the Children’s Hospital of Philadelphia, she cared for some of the first patients treated with CD19 CAR T cells, learning the power of this therapy first-hand. During her fellowship in Pediatric Hematology/Oncology at the Johns Hopkins/National Cancer Institute combined program, she worked with Dr. Terry Fry. She evaluated the mechanism of CD22 CAR T cell relapse in patients by developing an antigen escape model and establishing a deeper understanding of the effects of antigen density on CAR-T phenotype, expansion, and persistence (Fry…Ramakrishna…Mackall Nat Med, 2018; Ramakrishna, et al., Clinical Cancer Research, 2019). Since arriving at Stanford, Dr. Ramakrishna leads an interdisciplinary team that designs, develops, and successfully implements a robust correlative science platform for our novel CAR-T therapies. Analyzing patient samples from our first-in-human GD2 CAR-T trial (NCT04196413) treating a universally fatal cancer, diffuse midline glioma (DMG), we identified that intracerebroventricular CAR-T administration correlates with enhanced pro-inflammatory cytokines and reduced immunosuppressive cell populations in cerebrospinal fluid as compared to intravenous CAR-T administration (Majzner*, Ramakrishna*, et al., Nature 2022 *co-first authors). Her research program evaluates unique sets of patient samples using novel single-cell immune profiling to identify the drivers of CAR-T success or failure. Building on these findings, her team assesses approaches to enhance CAR-T efficacy and translate these findings to the clinic.

    Clinically, Dr. Ramakrishna cares for children with solid tumors and treats hematologic, solid, and brain tumor pediatric patients with CAR T cell therapies in the Cancer Cellular Therapies program.

  • Mahalakshmi Ramamurthy

    Mahalakshmi Ramamurthy

    Basic Life Research Scientist, Peds/Developmental-Behavioral Pediatrics

    BioI am a postdoctoral scholar working with Dr. Jason Yeatman. With a background in vision science, psychophysics and developmental cognitive neuroscience my long-term goal is to study the intersection of basic visual mechanisms and various neurodevelopmental disorders and to extend this understanding in creating effective early screening tools, and in advancing evidence-based therapeutic and remediation programs. Inherent to this interest is the need for developmental data in large and demographically diverse populations. I strongly believe that such inclusive research not only contributes to scientific advancements but can go beyond to bridge health and education disparities.

    https://sites.google.com/view/maha-ramamurthy/bio

  • Julia Raney

    Julia Raney

    Clinical Assistant Professor, Pediatrics - Adolescent Medicine

    Current Research and Scholarly InterestsAdolescents are dying from drug overdoses at unprecedented rates, largely secondary to fentanyl contamination in the drug supply. A Youth Overdose Prevention Toolkit for school-based health centers is needed to combat this trend. The toolkit should include key stakeholder-informed harm reduction approaches that focus on reducing injury or death from fentanyl and other opioids without exclusively recommending abstinence; this approach is evidence-based and critical to saving lives.

  • Anoop Rao

    Anoop Rao

    Clinical Associate Professor, Pediatrics - Neonatal and Developmental Medicine

    Current Research and Scholarly InterestsWearable senors, unobtrusive vital sign monitoring, natural language processing/text mining

  • Lindsey Rasmussen

    Lindsey Rasmussen

    Clinical Associate Professor, Pediatrics - Critical Care
    Clinical Associate Professor (By courtesy), Neurology & Neurological Sciences

    Current Research and Scholarly InterestsMy research interests reside in the field of Neurocritical Care Medicine and stem from my experience developing and directing Stanford's comprehensive Pediatric Neurocritical Care program. I am interested in neuro-prognostication and neuro-monitoring in the pediatric intensive care setting. These interests are integrated clinically to focus on optimal care for pediatric patients with neurologic injury, through specialized nursing and physician care, protocols, and physiologic considerations.

  • Caroline E. Rassbach

    Caroline E. Rassbach

    Clinical Professor, Pediatrics
    Clinical Professor, Emergency Medicine
    Clinical Professor, Emergency Medicine

    Current Research and Scholarly InterestsMedical education including learner assessment, program development and mentoring and coaching in medicine.