School of Medicine
Showing 691-700 of 709 Results
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Roham Zamanian
Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly Interests1. Development and evaluation of prognostic and diagnostic integral biomarkers in PAH.
2. Prevalence and Treatment of Insulin Resistance in PAH.
3. Role of inflammation and proteomic signature in PAH
4. Development of novel therapeutics (bench to bedside) including FK506 & Elastase Inhibition in PAH.
5. Assessment of Vasoreactivity (gain and loss) in pulmonary arterial hypertension
6. Assessment of microvascular function in PAH. -
Richard Zare
Marguerite Blake Wilbur Professor of Natural Science and Professor, by courtesy, of Physics
On Leave from 10/01/2024 To 12/31/2024Current Research and Scholarly InterestsMy research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.
Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.
Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:
The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.
Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells. -
Christopher K. Zarins
Walter Clifford Chidester and Elsa Rooney Chidester Professor of Surgery, Emeritus
Current Research and Scholarly InterestsHemodynamic factors in atherosclerosis, pathogenesis of, aortic aneurysms, carotid plaque localization and complication, anastomotic intimal hyperplasia, vascular biology of artery wall, computational fluid dynamics as applied to blood flow and vascular disease.
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James L. Zehnder, M.D.
Professor of Pathology (Research) and of Medicine (Hematology)
Current Research and Scholarly InterestsMy main research and clinical interests include molecular pathogenesis of acquired cytopenias, genetic testing for inherited non-malignant hematologic disorders, next-generation sequencing approaches to T and B cell clonality testing, somatic mutations in cancer and assessment of minimal residual disease in cancer patients.
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Hao Zhang
Instructor, Cardiovascular Institute
BioI earned my M.D. from Peking Union Medical College, Tsinghua University. Subsequently, I completed my residency and served as a cardiac fellow at Fuwai Hospital, where I developed a strong foundation in the pathophysiology of cardiovascular diseases.
As a postdoctoral researcher and instructor in Dr. Joseph Wu’s lab at Stanford, I established a protocol to derive cardiac fibroblasts (CFs) from human iPSCs, providing an unlimited source of cells for studying cardiac fibrosis. This method generates homogenous iPSC-derived CFs that remain quiescent yet responsive to profibrotic stimuli. Notably, this protocol played a crucial role in developing a multiscale drug discovery platform that integrates human iPSCs, 3D-engineered heart tissues, and animal models of heart failure. Using this platform, I discovered novel signaling pathways and therapeutic targets for cardiac fibrosis. My most recent work has been published in Cell (https://doi.org/10.1016/j.cell.2024.09.034). -
Huaiyu Zhang
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
BioDr. Zhang obtained her MS in Neuroscience from the University of Southern California and earned her PhD in Clinical Psychology from Emory University. She completed both her predoctoral internship and postdoctoral fellowship at Emory University School of Medicine. Prior to joining Stanford in 2023, Dr. Zhang supported survivors of interpersonal violence at the University of California San Francisco Trauma Recovery Center for over seven years. Dr. Zhang embraces an integrative, contextualized, evidence-informed, and strength-based approach to teaching, supervision, and clinical care. She provides services in English and Mandarin.
