School of Medicine
Showing 301-320 of 368 Results
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Gavin Sherlock
Professor of Genetics
Current Research and Scholarly InterestsEvolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species
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Mahasish Shome
Postdoctoral Scholar, Genetics
BioDr. Mahasish Shome is interested in understanding the underlying mechanism of disease progression. He uses various omics profiling to identify biomarkers relevant to the disease. He studies antibodies, cytokines, proteins and microbiome profile to decipher the connection of disease with markers. Connecting various omics provide a holistic overview of the disease profile and can help in early diagnosis, understanding disease state and drug/vaccine effectiveness.
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Arend Sidow
Professor of Pathology and of Genetics
Current Research and Scholarly InterestsWe have a highly collaborative research program in the evolutionary genomics of cancer. We apply well-established principles of phylogenetics to cancer evolution on the basis of whole genome sequencing and functional genomics data of multiple tumor samples from the same patient. Introductions to our work and the concepts we apply are best found in the Newburger et al paper in Genome Research and the Sidow and Spies review in TIGS.
More information can be found here: http://www.sidowlab.org -
Michael Snyder, Ph.D.
Stanford W. Ascherman Professor of Genetics
Current Research and Scholarly InterestsOur laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states
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Lars Steinmetz
Dieter Schwarz Foundation Endowed Professor
Current Research and Scholarly InterestsThe Steinmetz lab develops genomic technologies to study the genetic basis of complex phenotypes, the mechanisms of gene regulation, and the molecular systems underpinning disease. We’re leveraging biological insights across scales and organisms to predict, diagnose, treat and ultimately prevent disease.
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Han Sun
Postdoctoral Scholar, Genetics
Biostatistician 2, Pediatrics - EndocrinologyBioHan had been a postdoc with Dr. Steinmetz at the genetics department for five years, working on both cancers and heart diseases, trying to understand the mechanisms linking from variants to disease phenotypes. This led to a few very interesting findings of aberrant splicing regulation, such as splicing-mediated readthrough stabilization (SRS), one more mechanism for oncogene activation in multiple types of cancers, and tissue-specific splicing of a mitochondrial inner membrane protein, suggesting a molecular connection between deficiency in energy-supplying and dilated cardiomyopathy.
After being a senior computational biologist with Dr. Gloyn, who has been dedicated to the research of type 2 diabetes for decades, Han switched to the field of this multifactorial metabolic disease. It did take some courage to make such a switch at his post-postdoc stage, however, Han has a consistent interest in studying PG&E, which is not pacific gas and electric nearby, but the interaction between phenotype, genotype, and environment. With years of hands-on experience in statistical modeling and the analysis of next-generation sequencing and mass spectrometry data, in addition to a good understanding of disease genetics, cancer biology, and systems biology, Han is highly confident that he will enjoy the adventure and contribute to our understanding of diabetes. -
Vidyani Suryadevara
Instructor, Genetics
Current Research and Scholarly InterestsA Bioengineer by training, she has a breadth of experiences across different scientific disciplines including pulmonary diseases, Alzheimer’s disease, and musculoskeletal disorders, wherein her research projects involved unraveling signaling mechanism behind the disease in order to identify new therapeutic targets and developing imaging modalities for early diagnosis of the disease, thus eventually improving the quality of life in patients. Her current work has been centered around age-associated pathophysiologies like osteoarthritis and Alzheimer's Disease. Her research currently focuses on the clinical translation of a novel noninvasive multimodality imaging approach to detect senescence in osteoarthritis and Alzheimer's Disease and understand the senescence biology in these age-associated diseases.
She has led teams of renowned senescence scientists across the US to develop expert recommendations for biomarkers for senescence. She is also a faculty fellow in the Center for Innovation at Global Health, wherein her focus is to develop region-specific lifestyle interventions to prevent dementia.
