School of Medicine
Showing 61-80 of 117 Results
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Karla Kirkegaard
Violetta L. Horton Professor and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe biochemistry of RNA-dependent RNA polymerase function, the cell biology of the membrane rearrangements induced by positive-strand RNA virus infection of human cells, and the genetics of RNA viruses, which, with their high error rates, live at the brink of error catastrophe, are investigated in the Kirkegaard laboratory.
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Holden Maecker
Professor (Research) of Microbiology and Immunology
Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.
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Edward Mocarski
Professor of Microbiology and Immunology, Emeritus
Current Research and Scholarly InterestsMy research interests focused on the biology and pathogenesis of cytomegalovirus (CMV), an opportunistic pathogen that causes significant disease worldwide, reporting discoveries in areas of CMV gene regulation, DNA replication and packaging, maturation, impact on the host cell, disease pathogenesis, latency and reactivation, host cell death signaling and chemokine system. In the last 20 years of my academic career, we studied viral cell death suppressors and discovered ZBP1-RIPK3 necroptosis.
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Denise M. Monack
Martha Meier Weiland Professor in the School of Medicine
Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.
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Antonio J. Pagán
Assistant Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe Pagán lab is interested in the regulation of immunity and pathogenesis in tuberculosis (TB). TB is characterized by the formation of multicellular aggregates of immune cells called granulomas. We leverage the powerful genetics and imaging capabilities of genetically diverse fish models of TB, which capture key features of human TB granulomas, to address fundamental questions in mycobacterial pathogenesis and granuloma immunobiology.
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Peter Parham
Professor of Structural Biology and, by courtesy, of Microbiology and Immunology
Current Research and Scholarly InterestsThe Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors.
