School of Medicine
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Anthony Machi, MD
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. Anthony Machi is a double-board-certified, fellowship-trained anesthesiologist and pain management specialist with Stanford Health Care. He is also a clinical associate professor in the Department of Anesthesiology, Perioperative, and Pain Medicine, Division of Pain Medicine at Stanford University School of Medicine.
Dr. Machi diagnoses and treats a wide range of pain conditions, including acute and chronic postsurgical pain, nerve-related (neuropathic) pain, and pain affecting the back, neck, and joints. He specializes in using minimally invasive techniques to relieve pain and enhance quality of life for his patients who are recovering after surgery.
Dr. Machi’s research interests include using ultrasound to study the greater occipital nerve in people with greater occipital neuralgia. He has also studied patient outcomes and pain management strategies for many types of surgery, including minimally invasive valve surgery and major shoulder surgery.
Dr. Machi has published his research in peer-reviewed journals, such as Seminars in Cardiothoracic and Vascular Anesthesia, Regional Anesthesia & Pain Medicine, Anesthesia & Analgesia, and PAIN. He has also presented to his peers at national and regional meetings, including the annual meetings of the American Society of Anesthesiologists (ASA), the American Society of Regional Anesthesia and Pain Medicine (ASRA), and the Texas Society of Anesthesiologists.
Dr. Machi is a member of the American Academy of Pain Medicine, ASA, ASRA, the North American Neuromodulation Society, and the World Academy of Pain Medicine United. -
M Bruce MacIver
Professor (Research) of Anesthesiology, Perioperative and Pain Medicine, Emeritus
Current Research and Scholarly InterestsWe study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.
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Crystal Mackall
Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Current Research and Scholarly InterestsRecent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon.
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Kristen Klepac MacKenzie, MD
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. Kristen MacKenzie is a Clinical Assistant Professor in the Department of Anesthesiology, Perioperative, and Pain Medicine. Dr. MacKenzie graduated AOA with a MD from UCSF and then completed her anesthesia residency and pain medicine fellowships at Stanford. She works at the Stanford Pain Management Center with specialty interests in chronic pelvic and abdominal pain, as well as peripartum pain. She is the co-director for the Stanford Pelvic Pain Program as well as part of the Stanford Pelvic Health Center for interdisciplinary, multimodal care.
She completed a Stanford Faculty Medical Humanities Fellowship, focusing on the role of communication and the arts in modern medicine. She serves as the co-director for the Women's Sexual Dysfunction Case Conference. She is active in the American Academy of Pain Medicine (AAPM), and for the 2026-2027 year is serving as the Women in Pain Medicine Shared Interest Group (SIG) Co-Chair as well as a Director-at-large.
Outside of work, she enjoys being outdoors in the Bay Area, trail running, and spending time with her husband and two boys.
Clinical focus:
Pelvic pain, due to multiple causes including:
Dyspareunia
Painful Bladder Syndrome/ Interstitial cystitis/ Dysuria
Endometriosis
Fibroids
Pelvis Congestion Syndrome
Pelvic Floor Dysfunction
Pudendal Nerve Pain
Rectal/Anal Pain
Vulvar Pain/ Vulvodynia/ Vaginismus
Nerve entrapment syndromes, including hernia nerve entrapment
Post-partum and Peri-partum pain
Abdominal pain
Musculoskeletal pain
New Patients: Please have your primary treating provider place a referral to Stanford Pain Clinic and specify Pelvic Pain, Dr. MacKenzie. -
Sean Mackey, M.D., Ph.D.
Redlich Professor, Professor of Anesthesiology, Perioperative, and Pain Medicine (Adult Pain) and, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsMultiple NIH funded projects to characterize CNS mechanisms of human pain. Comparative effectiveness of cognitive behavioral therapy and chronic pain self-management within the context of opioid reduction (PCORI funded). Single session pain catastrophizing treatment: comparative efficacy & mechanisms (NIH R01). Development and implementation of an open-source learning healthcare system, CHOIR (http://choir/stanford.edu), to optimize pain care and innovative research in real-world patients.
