School of Medicine
Showing 1-10 of 18 Results
-
Andrea Cipriano
Instructor, Obstetrics & Gynecology - Reproductive Biology
BioDr Andrea Cipriano is an instructor at the Stem Cell Institute and at the Ob/Gyn department at Stanford School of medicine. Since the beginning of his career he was driven by a deep interest in the complexities of life emerging from just a single cell, harboring all the instructions to produce a fully functional organism. His academic journey began with a Bachelor's in Biotechnology and progressed to a Master's in Genomic Biotechnology, where he delved into the intricate world of RNA. During his PhD, Andrea focused on long non-coding RNAs and their pivotal role in cell differentiation, a topic that continues to fascinate him in his current research. He works in the Sebastiano lab, and he is directing several projects, including studying the transcription factor TBX1 during development of the Pharyngeal endoderm, and exploring the impact of time on Chromatin Structure, particularly in the context of aging and its potential reversal. As an instructor, Andrea has been teaching for 4 years at the intensive CIRM stem cell class biology course. Teaching is a big passion that fuels his academic pursuits. His dedication to education stems from a deep-seated belief in the transformative power of knowledge, which is what initially propelled him into the academic world.
-
Margaret T. Fuller
Reed-Hodgson Professor of Human Biology, Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
On Leave from 04/01/2024 To 07/19/2024Current Research and Scholarly InterestsRegulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.
-
Aaron Hsueh
Professor of Obstetrics and Gynecology (Reproductive and Stem Cell Biology), Emeritus
Current Research and Scholarly InterestsHormonal regulation of ovarian function; gonadotropin receptors and related genes, bioinformatic ananlyses of polypeptide hormones and receptors, follicle recruitment and GDF-9; analysis of oocyte and ovarian-expressed genes.
-
Matteo Amitaba Mole'
Assistant Professor of Obstetrics and Gynecology (Reproductive & Stem Cell Biology)
Current Research and Scholarly InterestsThe research focus of our laboratory is centered on investigating the complex process of human embryo implantation. Due to the limited availability of suitable model systems and inability to directly observe this process in vivo, this has been traditionally referred to as the enigmatic stage of human embryonic development.
The successful implantation of an embryo is crucial for the establishment of a healthy pregnancy. During the transition between the first and second week of gestation, the human embryo must securely implant into the maternal uterus, initiating development of the placenta to receive necessary nutrients and oxygen for its growth until birth.
However, the process of implantation in humans is highly susceptible to failure, with a significant percentage of embryos unable to develop beyond this stage leading to early miscarriages. This clinically observed "implantation barrier" often requires patients to undergo numerous cycles of IVF treatment, with no guarantee of a successful pregnancy outcome.
The primary objective is to increase the understanding of maternal-embryo interactions initiated at implantation, with the goal of developing clinical interventions to address the high incidence of implantation failures underlying pre-clinical miscarriages.