School of Medicine


Showing 1-100 of 169 Results

  • Kimberly Allison

    Kimberly Allison

    Professor of Pathology

    Current Research and Scholarly InterestsDr. Allison’s clinical expertise is in breast pathology. Her research interests include how standards should be applied to breast cancer diagnostics (such as ER and HER2 testing), the utility of molecular panel-based testing in breast cancer, digital pathology applications and identifying the most appropriate management of specific pathologic diagnoses.

  • Michael Angelo

    Michael Angelo

    Associate Professor of Pathology

    BioMichael Angelo, MD PhD is a board-certified pathologist and assistant professor in the department of Pathology at Stanford University School of Medicine. Dr. Angelo is a leader in high dimensional imaging with expertise in tissue homeostasis, tumor immunology, and infectious disease. His lab has pioneered the construction and development of Multiplexed Ion Beam Imaging by time of flight (MIBI-TOF). MIBI-TOF uses secondary ion mass spectrometry and metal-tagged antibodies to achieve rapid, simultaneous imaging of dozens of proteins at subcellular resolution. In recognition of this achievement, Dr. Angelo received the NIH Director’s Early Independence award in 2014. His lab has since used this novel technology to discover previously unknown rule sets governing the spatial organization and cellular composition of immune, stromal, and tumor cells within the tumor microenvironment in triple negative breast cancer. These findings were found to be predictive of single cell expression of several immunotherapy drug targets and of 10-year overall survival. This effort has led to ongoing work aimed at elucidating structural mechanisms in the TME that promote recruitment of cancer associated fibroblasts, tumor associated macrophages, and extracellular matrix remodeling. Dr. Angelo is the recipient of the 2020 DOD Era of Hope Award and a principal investigator on multiple extramural awards from the National Cancer Institute, Breast Cancer Research Foundation, Parker Institute for Cancer Immunotherapy, the Bill and Melinda Gates Foundation, and the Human Biomolecular Atlas (HuBMAP) initiative.

  • Euan A. Ashley

    Euan A. Ashley

    Roger and Joelle Burnell Professor of Genomics and Precision Health, Professor of Medicine (Cardiovascular Medicine), of Genetics, of Biomedical Data Science and, by courtesy, of Pathology

    Current Research and Scholarly InterestsThe Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.

  • Jeffrey Axelrod

    Jeffrey Axelrod

    Professor of Pathology

    Current Research and Scholarly InterestsGenetic and cell biological analyses of signals controlling cell polarity and morphogenesis. Frizzled signaling and cytoskeletal organization.

  • Niaz Banaei

    Niaz Banaei

    Professor of Pathology and of Medicine (Infectious Diseases)

    Current Research and Scholarly InterestsHis research interests include (1) development, assessment, and improvement of novel infectious diseases diagnostics, (2) enhancing the quality of C. difficile diagnostic results, and (3) characterization of M. tuberculosis virulence determinants.

  • Ellen Jo Baron

    Ellen Jo Baron

    Professor of Pathology at the Stanford University Medical Center, Emerita

    Current Research and Scholarly InterestsNo current scientific activities. I am retired.

  • Dr. Gregory Bean

    Dr. Gregory Bean

    Associate Professor of Pathology

    BioDr. Bean is an Associate Professor who specializes in breast pathology. His research interests include molecular characterization of breast cancer subtypes and precursors. He is also involved with the training of residents and fellows on the breast service.

  • Sean Bendall

    Sean Bendall

    Associate Professor of Pathology

    Current Research and Scholarly InterestsOur goal is to understand the mechanisms regulating the development of human systems. Drawing on both pluripotent stem cell biology, hematopoiesis, and immunology, combined with novel high-content single-cell analysis (CyTOF – Mass Cytometry) and imagining (MIBI-Multiplexed Ion Beam Imaging) we are creating templates of ‘normal’ human cellular behavior to both discover novel regulatory events and cell populations as well as understand dysfunctional processes such as cancer.

  • Gerald Berry

    Gerald Berry

    Richard Kempson, M.D., Professor of Surgical Pathology

    Current Research and Scholarly InterestsCardiopulmonary and pulmonary transplant medicine; diagnostic surgical pathology

  • David Bingham

    David Bingham

    Clinical Assistant Professor, Pathology

    BioDavid Bingham MD is a clinical assistant pathologist specializing in gastrointestinal pathology. He is from Connecticut, graduated from Yale with a BA, and went to Columbia P&S for medical school. He did a residency in Pathology at Stanford University, graduated in 1992 and has been here ever since as a faculty member.

  • Matthew Bogyo

    Matthew Bogyo

    Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology

    Current Research and Scholarly InterestsOur lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include:

    1) Design and synthesis of novel chemical probes for serine and cysteine hydrolases.

    2) Understanding the role of hydrolases in bacterial pathogenesis and the human parasites, Plasmodium falciparum and Toxoplasma gondii.

    3) Defining the specific functional roles of proteases during the process of tumorogenesis.

    4) In vivo imaging of protease activity

  • Donald E. Born

    Donald E. Born

    Clinical Professor, Pathology

    BioDr. Born obtained his medical degree from the University of Virginia where he also completed a Ph.D. in Neuroscience. His next training occurred at the University of Washington as an Anatomic Pathology resident and Neuropathology fellow. He moved to Stanford in 2013 and as Clinical Professor of Pathology he sees a wide range of samples related to the field of neuropathology.

  • Raffick A.R. Bowen

    Raffick A.R. Bowen

    Clinical Professor, Pathology

    Current Research and Scholarly InterestsMy current research involves the investigation of immunoassay interferences from blood collection tube additives; particularly, silicone surfactants.

  • Scott D. Boyd, MD PhD

    Scott D. Boyd, MD PhD

    Stanford Professor of Food Allergy and Immunology and Professor of Pathology

    Current Research and Scholarly InterestsOur goal is to understand the lymphocyte genotype-phenotype relationships in healthy human immunity and in immunological diseases. We apply new technologies and data analysis approaches to this challenge, particularly high-throughput DNA sequencing and single-cell monoclonal antibody generation, in parallel with other functional assays.

  • Ryanne Ashley Brown, MD, MBA

    Ryanne Ashley Brown, MD, MBA

    Clinical Assistant Professor, Pathology
    Clinical Assistant Professor (By courtesy), Dermatology

    BioRyanne Brown, M.D., M.B.A., is a Clinical Assistant Professor of Pathology and (by courtesy) Dermatology. She completed her residency training in Anatomic and Clinical Pathology followed by Surgical Pathology and Dermatopathology fellowships at Stanford. She is board certified in both Anatomic Pathology and Clinical Pathology (American Board of Pathology) and Dermatopathology (American Boards of Pathology/Dermatology). Her interests include cutaneous lymphoma and histiocytic neoplasms.

  • Eugene Butcher

    Eugene Butcher

    Klaus Bensch Professor of Pathology

    Current Research and Scholarly InterestsOur interests include:
    1) The physiology and function of lymphocyte homing in local and systemic immunity;
    2) Biochemical and genetic studies of molecules that direct leukocyte recruitment;
    3) Chemotactic mechanisms and receptors in vascular and immune biology;
    4) Vascular control of normal and pathologic inflammation and immunity;
    5) Systems biology of immune cell trafficking and programming in tumor immunity.

  • Emily Chan

    Emily Chan

    Associate Professor of Pathology (Clinical Pathology)

    BioDr. Chan is an Associate Professor of Pathology at Stanford University. She completed her MD, PhD at New York University and Anatomic Pathology residency with subspecialty Genitourinary Pathology training at University of California-San Francisco (UCSF). She is AP board-certified. Dr. Chan has been a GU attending at UCSF for the past five years where she has successfully mentored numerous trainees in projects, publications, and career planning. Dr. Chan has co-authored more than 40 peer-reviewed research publications and has a particular interest in integrating molecular testing in diagnostic pathology, as well as recognition of prostate cancer architectural patterns than can help with prognosis and treatment decision making.

  • Howard Y. Chang, MD, PhD

    Howard Y. Chang, MD, PhD

    Virginia and D. K. Ludwig Professor of Cancer Research, Professor of Genetics and, by courtesy, of Pathology

    Current Research and Scholarly InterestsOur research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.

  • Vivek Charu

    Vivek Charu

    Assistant Professor of Pathology and of Medicine (Quantitative Sciences)

    BioI am a physician and a biostatistician. My clinical expertise is in the diagnosis of non-neoplastic kidney and liver disease (including transplantation). My research interests center on the design of observational studies and clinical trials, the analysis of observational data, and causal inference.

  • Greg Charville, MD, PhD

    Greg Charville, MD, PhD

    Associate Professor of Pathology

    BioDr. Charville has a special interest in the diagnosis of rare tumors that derive from bone and soft tissues, including muscle, fat, blood vessels, cartilage, and other connective tissues. He also specializes in the classification and study of diseases related to the gastrointestinal and hepatopancreatobiliary systems.

    Dr. Charville particularly enjoys working alongside Stanford's excellent physicians-in-training to classify the most diagnostically challenging cases in collaboration with pathologists from around the world, bringing to bear cutting-edge techniques for comprehensive histologic and molecular characterization in each case. This experience serves as the inspiration for laboratory-based investigation of the molecular underpinnings of human disease, focusing on genetic and epigenetic mechanisms of neoplasia and the translation of these mechanistic insights into novel diagnostic and predictive biomarkers.

  • Michael Cleary

    Michael Cleary

    Lindhard Family Professor of Pediatric Cancer Biology and Professor of Pathology, Emeritus

    Current Research and Scholarly InterestsThe role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer.

  • Maria Inmaculada Cobos Sillero

    Maria Inmaculada Cobos Sillero

    Associate Professor of Pathology

    Current Research and Scholarly InterestsOur lab uses cellular and molecular methods, single-cell technology, and quantitative histology to study human neurodegenerative diseases. Current projects include:

    - Using single-cell RNA-sequencing to understand selective vulnerability and disease progression in human Alzheimer’s disease brain

    - Investigating mechanisms of tau-related neurodegeneration in human brain

    - Studying the neocortical and limbic systems in Diffuse Lewy Body Disease (DLBD) at the single cell level

  • Le Cong

    Le Cong

    Assistant Professor of Pathology (Pathology Research) and of Genetics

    Current Research and Scholarly InterestsOur lab are developing gene-editing technologies, such as CRISPR systems for in vivo therapy, and cleavage-free techniques for large gene insertion via microbial recombinase. Our team also pioneers in single-cell tracking for cancer and immunology studies using novel CRISPR tools. To accelerate our work, we integrate AI and machine learning into these technologies, design and evolve proteins/RNAs, pushing frontiers in understanding and treating neurological and immunological disease.

  • Joanne Cornbleet

    Joanne Cornbleet

    Associate Professor of Pathology at the Stanford University Medical Center, Emerita

    Current Research and Scholarly InterestsAs medical director of the Hematology Laboratory, my main focus is service work, including laboratory administration, bone marrow pathology, and flow cytometry interpretation. Publications arise primarily from development or evaluation of laboratory methods or collections of unusual patient cases.

  • Helio Costa

    Helio Costa

    Adjunct Clinical Assistant Professor, Pathology

    BioHelio Costa, PhD, is a medical geneticist with expertise in oncology, medical genetics and genomics, computational biology, data science, software engineering, and product development. He is passionate about leveraging his interdisciplinary skillset to build and develop commercial-grade cancer diagnostic products and medical software that aid in patient care and clinical decision support. Currently he is Medical Director of Oncology at Natera, and an Adjunct Clinical Assistant Professor in the Department of Pathology at Stanford Medical School.

    Dr. Costa's research focuses on developing and implementing new medical diagnostic genetic tests and software for use in patient care. His research group developed DNA and RNA cancer diagnostic tests currently in use at Stanford Health Care as well as developing clinical algorithms using large-scale clinical laboratory datasets and patient electronic medical records to predict patient outcomes and aid in therapeutic clinical decision support. Additionally, Dr. Costa served as a co-Investigator in the NIH Clinical Genome Resource (ClinGen) Consortium, and led the engineering and product management teams developing FDA-recognized medical software applications used by healthcare providers, researchers, and biotechnology companies to define the clinical relevance of genes and pathogenicity of mutations identified in patients.

    Dr. Costa is the founding director of the Stanford Clinical Data Science Fellowship where post-doctoral fellows engage in interdisciplinary clinical research and embed in health care workflows learning, building and deploying real-world health data solutions in the Stanford Health Care system. He is currently an Attending Medical Geneticist for the Molecular Genetic Pathology Laboratory at Stanford Health Care where he previously served as an Assistant Lab Director.

    Dr. Costa received his BS in Genetics from University of California at Davis, his PhD in Genetics from Stanford University School of Medicine, and his ABMGG Clinical Molecular Genetics and Genomics fellowship training from Stanford University School of Medicine.

  • Tina Cowan

    Tina Cowan

    Professor of Pathology (Clinical) and, by courtesy, of Pediatrics (Genetics)

    Current Research and Scholarly Interestsscreening and diagnosis of patients with inborn errors of metabolism, including newborn screening, development of new testing methods and genotype/phenotype correlations.

  • Gerald Crabtree

    Gerald Crabtree

    David Korn, MD, Professor of Pathology and Professor of Developmental Biology

    Current Research and Scholarly InterestsChromatin regulation and its roles in human cancer and the development of the nervous system. Engineering new methods for studying and controlling chromatin and epigenetic regulation in living cells.

  • John W. Day, MD, PhD

    John W. Day, MD, PhD

    Professor of Neurology (Adult Neurology), of Pediatrics (Genetics) and, by courtesy, of Pathology

    Current Research and Scholarly InterestsOur Neuromuscular Division coordinates a comprehensive effort to conquer peripheral nerve and muscle disorders, including the muscular dystrophies, motor neuron disorders, neuromuscular junction abnormalities, and peripheral neuropathies. With patients and families foremost in mind, we have had success defining and combating these diseases, with research focused on identifying genetic causes, developing novel treatment, and maximizing patient function by optimizing current management.

  • Dylan Dodd

    Dylan Dodd

    Assistant Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsHarnessing the gut microbiome to treat human disease.

  • Fei Dong

    Fei Dong

    Associate Professor of Pathology

    BioDr. Dong is the Associate Director of Molecular Pathology at Stanford Health Care. His clinical interests include the implementation and interpretation of laboratory developed tests in diagnosis and patient care. Previous accomplishments include the development of novel bioinformatics algorithms to infer microsatellite instability and allogeneic contamination from cancer sequencing data. Before arriving at Stanford, Dr. Dong was on faculty at Brigham and Women’s Hospital/Harvard Medical School for nine years, where he established a track record in education and mentorship and was the recipient of both the Anatomic Pathology and Clinical Pathology resident teaching awards. Dr. Dong has served on national/international committees for the Association for Molecular Pathology, the Clinical and Laboratory Standards Institute, and the College of American Pathologists and serves on the editorial boards of multiple academic journals, including the Archives of Pathology and Laboratory Medicine, the Journal of Molecular Diagnostics, and Modern Pathology.

  • Lawrence Eng

    Lawrence Eng

    Professor (Research) of Pathology, Emeritus

    Current Research and Scholarly InterestsAstrocytes make up a substantial proportion of the central nervous system (CNS) and participate in a variety of important physiologic and pathologic processes. They are characterized by vigorous response to diverse neurologic insults.

  • Edgar Engleman

    Edgar Engleman

    Professor of Pathology and of Medicine (Immunology and Rheumatology)

    Current Research and Scholarly InterestsDendritic cells, macrophages, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer, autoimmune disease, neurodegenerative disease and metabolic disease.

  • Dean W. Felsher

    Dean W. Felsher

    Professor of Medicine (Oncology) and of Pathology

    Current Research and Scholarly InterestsMy laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

  • Marcelo Fernandez Vina

    Marcelo Fernandez Vina

    Professor of Pathology

    BioMarcelo Fernández-Viña, Ph.D., D (ABHI) is a Professor for the Department of Pathology at Stanford University Medical School and serves as Director of the Histocompatibility, Immunogenetics and Disease Profiling Laboratory at this institution. He has been working in the fields of Histocompatibility and Immunogenetics since 1982. He earned a degree in Biochemistry from the School of Basic Sciences in Rosario, Argentina, and his Ph.D. in Internal Medicine from the University of Buenos Aires Medical School in Argentina. Previously he held a position as a Professor in the Department of Laboratory Medicine at the University of Texas M.D. Anderson Cancer Center in Houston. He has more than 180 peer reviewed publications, many of them focusing on HLA variation in multiple world populations, identifying susceptibility and resistance factors for diseases and in the impact of HLA mismatches in allogeneic transplantation; and 59 book chapters. He served as expert Consultant for Donor Searches for NMDP and as President Elect, President and Past President of the American Society for Histocompatibility and Immunogenetics. He served as a member of the Board of Directors and the Executive Committee for the United Network for Organ Sharing. He served as Co-Chair of the Immunobiology Committee of the CIBMTR; He also served as a member of the HHS Advisory Council on Blood Stem Cell Transplantation (ACBSCT).He serves as HLA Expert Consultant for the NMDP for the HRSA contract and is a member of the Histocompatibility Advisory Group for NMDP. He is Councilor of the International Histocompatibility Workshop and a member of the WHO Nomenclature Committee for Factors of the HLA System and was Chairman of the (17th) International HLA & Immunogenetics Workshop, and Past President of the International HLA & Immunogenetics Workshop.

  • Sebastian Fernandez-Pol

    Sebastian Fernandez-Pol

    Clinical Assistant Professor, Pathology

    BioDr. Sebastian Fernandez-Pol is an academic hematopathologist with fellowship training in hematopathology and dermatopathology. He has a particular interest in improving diagnostic accuracy for cutaneous lymphoproliferative disorders. Dr. Fernandez-Pol received his B.A. in chemistry with a concentration in biochemistry from the Washington University in St. Louis in 2003, his MD and PhD from Northwestern University in 2013, and completed his anatomic pathology and clinical pathology residency, hematopathology fellowship, and dermatopathology fellowship at Stanford University in 2019.

  • Andrew Fire

    Andrew Fire

    George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics

    Current Research and Scholarly InterestsWe study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".

  • Ann Folkins

    Ann Folkins

    Associate Professor of Pathology

    Current Research and Scholarly InterestsDr. Folkins' interest is in gynecologic and obstetric pathology, specifically in ovarian and endometrial malignancies and placental clinical-pathologic disorders.

  • Steven Foung

    Steven Foung

    Professor of Pathology
    On Partial Leave from 03/18/2024 To 02/22/2025

    Current Research and Scholarly InterestsOur research focus is define correlates of protection against hepatitis C virus and other viral pathogens. Detailed characterization of broadly neutralizing human or nonhuman primate monoclonal antibodies against these agents will create high-resolution, functional maps of linear and nonlinear epitopes comprising the major binding sites of both isolate-specific and broadly neutralizing antibodies for rational vaccine design.

  • Susan Galel

    Susan Galel

    Associate Professor of Pathology at the Stanford University Medical Center, Emerita

    Current Research and Scholarly InterestsTransfusion-transmitted infections and donor screening for infectious diseases. National policies for blood banks. Enhancement of transfusion safety and effectiveness, with a focus on quality assurance in blood banking and transfusion therapy; transfusion medicine education; pediatric and adult transfusion therapy.

  • Stephen J. Galli, MD

    Stephen J. Galli, MD

    Mary Hewitt Loveless, MD, Professor in the School of Medicine and Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsThe goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease. We study both the roles of mast cells, basophils, and IgE in normal physiology and host defense, e.g., in responses to parasites and in enhancing resistance to venoms, and also their roles in pathology, e.g., anaphylaxis, food allergy, and asthma, both in mice and humans.

  • Sharon Markham Geaghan

    Sharon Markham Geaghan

    Associate Professor of Pathology at the Stanford University Medical Center, Emerita

    Current Research and Scholarly InterestsPediatric Hematopathology, Pediatric Laboratory Medicine and Pathology

  • Bertil Glader

    Bertil Glader

    Stanford Medicine Professor of Pediatric Hematology/Oncology and Professor, by courtesy, of Pathology

    Current Research and Scholarly InterestsHematology/Oncology, biology, and treatment of bone marrow failure disorders, hereditary coagulation disorders-clinical trials.

  • Lawrence Tim Goodnough

    Lawrence Tim Goodnough

    Professor of Pathology and of Medicine (Hematology), Emeritus

    Current Research and Scholarly InterestsImproving blood utilization
    Promoting alternatives to blood transfusion
    Quality improvements

  • Dita Gratzinger

    Dita Gratzinger

    Professor of Pathology

    Current Research and Scholarly InterestsI have research interests in the interaction of hematolymphoid neoplasia with the microenvironment. For example, I use a combination of immunohistochemistry, immunofluorescence and image analysis techniques to evaluate the mesenchymal stromal cell compartment in myelodysplastic syndrome (pre-leukemic bone marrow failure disorder). I also have interests in lymphoma vasculature and the tropism of lymphoma for specific types of vasculature.

  • Wei Gu

    Wei Gu

    Assistant Professor of Pathology

    BioWei Gu, MD, PhD, is a physician, engineer, and scientist whose research focus is methylation classification within the area of molecular pathology. He has pioneered technologies in cell-free DNA 'liquid biopsy' testing, CRISPR diagnostics, clinical metagenomic sequencing, non-invasive prenatal testing, and COVID diagnostics. Dr. Gu has received awards from the Burroughs Wellcome Career Award and the National Cancer Institute. As a physician, he is a board-certified molecular and clinical pathologist and maintains a clinical practice at Stanford Healthcare.

  • Michael Hendrickson

    Michael Hendrickson

    Professor of Pathology at the Stanford University Medical Center, Emeritus

    Current Research and Scholarly InterestsDiagnosis of progressive stages of uterine cancer; classification of ovarian tumors; breast cancer diagnosis and prognostic factors, soft tissue neoplasm, uterine mesenchymal neoplasm.

  • John Higgins

    John Higgins

    Professor of Pathology

    Current Research and Scholarly InterestsI work as a diagnostic surgical pathologist doing translational research in renal neoplasia and medical renal disease and neoplastic and medical liver disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology.

  • Jody Elizabeth Hooper

    Jody Elizabeth Hooper

    Associate Professor of Pathology

    Current Research and Scholarly InterestsI am the Director of the Research Autopsy Collaboration at Stanford (RACS) to collect organs and tissues from decedent donors for cancer and disease research. https://med.stanford.edu/racs
    I have a number of research interests associated with my autopsy work, including how the time interval between death and collection (the PMI) affects the condition and research viability of the collected tissue, how valuable blood and tissue cultures behave after death, and how autopsy results affect clinical practice in an established information loop. I have projects exploring physician and family attitudes towards autopsy and the utilization of rapid autopsy tissue in characterizing cancer evolution from genetic and immunologic standpoints.

  • Dikran Horoupian

    Dikran Horoupian

    Professor (Clinical) of Pathology, Emeritus

    Current Research and Scholarly InterestsNeuropathology of:
    1. Neurodegenerative diseases
    2. Neurodevelopmental disorders
    3. CNS neoplasms
    4. Nerve & muscle diseases

  • Brooke Howitt

    Brooke Howitt

    Associate Professor of Pathology

    BioDr. Howitt is a gynecologic and sarcoma pathologist, with academic interests in gynecologic mesenchymal tumors and morphologic and clinical correlates of molecular alterations in gynecologic neoplasia.

  • Michael R. Howitt

    Michael R. Howitt

    Assistant Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsOur lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.

  • Chris C.S. Hsiung

    Chris C.S. Hsiung

    Instructor, Pathology

    BioI am a molecular biologist and laboratory medicine physician. I am interested in understanding how cells turn genes on or off, and engineering ways we can turn genes on or off for biological discovery and therapeutic benefit.

    In my postdoctoral work advised by Dr. Luke Gilbert (Arc Institute), I developed multiAsCas12a (multiplexed transcriptional interference Acidaminococcus Cas12a), a new functional genomics platform capable of higher-order combinatorial chromatin targeting of multiple coding and non-coding genetic elements per cell, including in pooled 6-plex CRISPRi screens. I proposed a group testing experimental framework to efficiently survey higher-order combinatorial spaces of genetic perturbations. I applied this approach to discover new enhancer elements and dissect the combinatorial logic of cis-regulatory elements. This work is available as a preprint: https://www.biorxiv.org/content/10.1101/2023.09.18.558350v2

    In my prior work as an MD-PhD student co-advised by Dr. Arjun Raj and Dr. Gerd Blobel at the Univ. of Pennsylvania, I led several studies focused on how gene regulatory information is maintained or altered through mitosis in mammalian cells, using epigenomics methods, single-molecule RNA imaging, and computational analysis.

  • Peter K.  Jackson

    Peter K.  Jackson

    Professor of Microbiology and Immunology (Baxter Labs) and of Pathology

    Current Research and Scholarly InterestsCell cycle and cyclin control of DNA replication .

  • Siddhartha Jaiswal

    Siddhartha Jaiswal

    Assistant Professor of Pathology

    Current Research and Scholarly InterestsWe identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.

  • Kristin Jensen

    Kristin Jensen

    Associate Professor of Pathology

    Current Research and Scholarly InterestsI am a clinical translational investigator with a primary interest in breast cancer biology, and the use of investigational and clinical ancillary techniques such as gene and tissue microarray analysis and immunohistochemistry in the diagnosis and prognosis of this disease. As a practicing cytopathologist, I also have an interest in improving the fine needle aspiration biopsy diagnosis of breast lesions, again using immunohistochemistry and gene expression analysis as adjuncts to cytomorphology.

  • Neeraja Kambham

    Neeraja Kambham

    Professor of Pathology

    Current Research and Scholarly InterestsDr. Kambham's research interests primarily involve medical diseases and transplantation pathology of the kidney and liver.

  • Maya M. Kasowski

    Maya M. Kasowski

    Assistant Professor of Pathology, of Medicine (Pulmonary, Allergy and Critical Care Medicine) and, by courtesy, of Genetics

    BioI am a clinical pathologist and assistant professor in the Departments of Medicine, Pathology, and Genetics (by courtesy) at Stanford. I completed my MD-PhD training at Yale University and my residency training and a post-doctoral fellowship in the Department of Genetics at Stanford University. My experiences as a clinical pathologist and genome scientist have made me passionate about applying cutting-edge technologies to primary patient specimens in order to characterize disease pathologies at the molecular level. The core focus of my lab is to study the mechanisms by which genetic variants influence the risk of disease through effects on intermediate molecular phenotypes.

  • Christina Kong

    Christina Kong

    Professor of Pathology

    Current Research and Scholarly InterestsImproving the accuracy of cytologic diagnosis through the use of ancillary techniques on specimens obtained by fine needle aspiration biopsy.

    Identifying potential indicators of prognosis in head and neck squamous cell carcinomas.

    Evaluating the utility of immunohistochemical stains in refining the diagnosis of squamous dysplasia of the cervix, vulva, and head and neck.

  • Christian Kunder

    Christian Kunder

    Clinical Associate Professor, Pathology

    Current Research and Scholarly InterestsMy main interest is in understanding the biology of human neoplasms, using traditional histopathology, molecular genetic techniques, and other modalities. In particular, I am interested in soft tissue and genitourinary neoplasms, especially prostate cancer.

    I am also interested in the classification and nomenclature of neoplasms and in practical research that helps us refine these, using a variety of techniques but still principally guided by histopathology.

    I also work on developing next generation sequencing-based tests for genotyping tumors and in expanding the scope of this testing with the goal of identifying patients eligible for novel targeting therapies.

  • Caleb Lareau

    Caleb Lareau

    Instructor, Pathology

    BioProfile moved to lab website: https://clareaulab.com/

  • Joseph (Joe) Lipsick

    Joseph (Joe) Lipsick

    Professor of Pathology and of Genetics

    Current Research and Scholarly InterestsFunction and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.

  • Amy Lo

    Amy Lo

    Adjunct Clinical Associate Professor, Pathology

    BioDr. Amy Lo is a pathologist with board certification in anatomic pathology, clinical pathology and molecular genetic pathology. She completed her MD and MS at the University of Illinois at Chicago and her residency in both anatomic and clinical pathology at Northwestern University. She then joined the faculty at Northwestern University as a Clinical Instructor and Advanced Gastrointestinal/Surgical Pathology Fellow. Amy then completed a molecular genetic pathology fellowship at Stanford University.

    In 2016, Amy joined Genentech as research pathology scientist supporting drug research and development with a focus in oncology and individualized drug development.
    Additionally, Amy continues clinical work as an Adjunct Clinical Associate Professor in pathology at Stanford University and Lucille Packard’s Children’s Hospital.

  • Jonathan Z. Long

    Jonathan Z. Long

    Associate Professor of Pathology

    BioDr. Jonathan Long is an Associate Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). His laboratory studies signaling pathways in mammalian energy metabolism. The long-term goal of this program is to discover new molecules and pathways that can be translated into therapeutic opportunities for obesity, metabolic disease, and other age-associated chronic diseases. Work from the laboratory has been recognized by numerous awards from the Alfred P. Sloan Foundation, the National Institutes of Health, the American Diabetes Association, and the Ono Pharma Foundation. Prior to arriving to Stanford, Dr. Long completed his Ph.D. in Chemistry at Scripps Research and his postdoctoral work at Harvard Medical School.

  • Teri A Longacre

    Teri A Longacre

    Richard L. Kempson, MD, Professor in Surgical Pathology

    Current Research and Scholarly InterestsGynecological, breast and gastrointestinal pathology with major emphasis on ovarian cancer and ovarian tumors of low malignant potential. Pathology of familial and hereditary breast-ovarian-GI cancer.

  • Alarice Cheng-Yi Lowe

    Alarice Cheng-Yi Lowe

    Associate Professor of Pathology

    BioDr. Lowe joined the School of Medicine faculty in 2019. She received her undergraduate degree in Biology from MIT and her medical degree at UCSD, prior to residency and cytology fellowship at UCLA. In 2011, she joined the faculty at Brigham and Women's Hospital where she developed a research focus on Circulating Tumor Cells (CTCs) and the application of new technology to improve clinical and molecular diagnostics. Clinically, her interests focus on Cytopathology and Genitourinary Pathology.

  • Bingwei Lu

    Bingwei Lu

    Professor of Pathology

    Current Research and Scholarly InterestsWe are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer’s and Parkinson’s diseases. We are using both Drosophila and mammalian models to address these fundamental questions.

  • Ruben Y. Luo

    Ruben Y. Luo

    Assistant Professor of Pathology

    Current Research and Scholarly InterestsApply top-down mass spectrometry and label-free immunoassay to the study and utilization of biomarker proteoforms in clinical diagnosis.

  • Magdalena Matusiak

    Magdalena Matusiak

    Instructor, Pathology

    Current Research and Scholarly InterestsMy research focuses on revealing clinically relevant prognostic markers associated with myeloid cell biology in solid malignancies. I currently. lead two main projects: first, using single-cell RNA Sequencing and bulk tissue genomics to discover tumor-associated macrophage (TAM) diversity and establish their prognostic and predictive markers, second: using multiplex tissue imaging (MIBI) to unravel prognostic markers of spatial heterogeneity in the colon cancer.

  • Joshua Menke

    Joshua Menke

    Clinical Assistant Professor, Pathology

    BioDr. Joshua Menke completed his hematopathology fellowship at Stanford and cytopathology fellowship at University of California San Francisco (UCSF). His clinical and research interests lie at the intersection of hematopathology, cytopathology and advanced single cell and cell free diagnostic techniques. As Associate Section Director of Clinical Flow Cytometry at Stanford, Dr. Menke is developing and validating new minimal residual disease assays for detecting low levels of myeloid and lymphoid neoplasms in the post-treatment setting as well as multiple other 12 color flow assays with the latest markers for routine phenotyping. Dr. Menke is the receipient of the Paul E. Standjord Young Investigator Award from the Academy of Clinical Laboratory Scientists and Laurance J. Marton Award for Excellence in Research from UCSF for his translational work on CALR mutations at the UCSF Molecular Diagnostics Laboroatory. Currently, he is spearheading novel genomic and proteomic analytic techniques to study cytology samples obtained for lymphoma diagnostics, including sequencing cell-free tumor DNA from supernatant samples. Dr. Menke is a founding member of the Cytology-Hematopathology Interinstitution Collaboration (CHIC) that aims to study the performance of cytology samples in diagnosing lymphoma across large datasets from five academic institutions and currently chairs that group spearheading large clinical research studies.

  • Sara Michie

    Sara Michie

    Professor of Pathology (Research), Emerita

    Current Research and Scholarly InterestsLymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules.

  • Paul Salomon Mischel

    Paul Salomon Mischel

    Fortinet Founders Professor and Professor, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsMy research bridges cancer genetics, signal transduction and cellular metabolism as we aim to understand the molecular mechanisms that drive cancer development, progression, and drug resistance. We have made a series of discoveries that have identified a central role for ecDNA (extrachromosomal DNA) in cancer development, progression, accelerated tumor evolution and drug resistance.

  • Michelle Monje

    Michelle Monje

    Milan Gambhir Professor of Pediatric Neuro-Oncology and Professor, by courtesy, of Neurosurgery, of Pediatrics, of Pathology and of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsThe Monje Lab studies the molecular and cellular mechanisms of postnatal neurodevelopment. This includes microenvironmental influences on neural precursor cell fate choice in normal neurodevelopment and in disease states.

  • Stephen B. Montgomery

    Stephen B. Montgomery

    Stanford Medicine Professor of Pathology, Professor of Genetics and of Biomedical Data Science
    On Partial Leave from 06/17/2024 To 08/15/2024

    Current Research and Scholarly InterestsWe focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches. See our website at http://montgomerylab.stanford.edu/

  • Thomas Montine, MD, PhD

    Thomas Montine, MD, PhD

    Stanford Medicine Professor of Pathology

    BioDr. Montine received his education at Columbia University (BA in Chemistry), the University of Rochester (PhD in Pharmacology), and McGill University (MD and CM). His postgraduate medical training was at Duke University, and he was junior faculty at Vanderbilt University where he was awarded the Thorne Professorship in Pathology. In 2002, Dr. Montine was appointed as the Alvord Endowed Professor in Neuropathology and Director of the Division of Neuropathology at the University of Washington. He was Director of the University of Washington Alzheimer’s Disease Research Center, one of the original 10 Centers in the US, and passed that responsibility to able colleagues. Dr. Montine was the founding Director of the Pacific Udall Center, a NINDS-funded Morris K. Udall Centers of Excellence for Parkinson’s Disease Research. In 2010, Dr. Montine was appointed Chair of the Department of Pathology at the University of Washington. In 2016, Dr. Montine was appointed Chair of the Department of Pathology at Stanford University where he is the Stanford Medicine Endowed Professor in Pathology.

    The focus of the Montine Laboratory is on the structural and molecular bases of cognitive impairment. The Montine Laboratory addresses this prevalent, unmet medical need through a combination of neuropathology, biomarkers for detection and progression of early disease, and experimental studies that test hypotheses concerning specific mechanisms of neuron injury and then develop novel approaches to neuroprotection. Our current approaches include small molecule precision therapeutics and cell replacement strategies for brain.

  • Saisindhu Narala, MD, MAS

    Saisindhu Narala, MD, MAS

    Clinical Assistant Professor, Dermatology
    Clinical Assistant Professor, Pathology

    BioDr. Narala completed her dermatology residency at the University of Texas at Houston and MD Anderson Cancer Center. She then completed a fellowship in dermatopathology at Stanford. Her clinical interests include general medical dermatology, dermatology in skin of color, and pigmentary disorders. She also has an interest in medical education.

  • Yasodha Natkunam, M.D., Ph.D

    Yasodha Natkunam, M.D., Ph.D

    Ronald F. Dorfman, MBBch, FRCPath Professor of Hematopathology

    Current Research and Scholarly InterestsMy research interests focus on the identification and characterization of markers of diagnostic and prognostic importance in hematolymphoid neoplasia.

  • Jeff Nirschl

    Jeff Nirschl

    Instructor, Pathology

    BioJeff Nirschl, M.D., Ph.D. is an Instructor in Pathology at Stanford University, Stanford, CA with clinical expertise in Neuropathology. He completed his Ph.D. in Neuroscience at the University of Pennsylvania under the supervision of Dr. Erika Holzbaur. During his thesis research, he investigated axonal transport and genetic forms of parkinsonism. He also developed computational image analysis workflows for fluorescence microscopy and digital pathology. His research interests include molecular motors and the neuronal cytoskeleton, the regulation of axonal transport in neurodegeneration, digital pathology, and quantitative image analysis using machine learning.
    https://orcid.org/0000-0001-6857-341X