School of Medicine


Showing 1-43 of 43 Results

  • Manuel R. Amieva

    Manuel R. Amieva

    Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly InterestsMy laboratory studies how bacteria colonize our bodies for long periods of time, and how interactions between bacteria and the epithelial surfaces of the gastrointestinal tract and skin may lead to disease. Epithelial surfaces are the first barrier against infection, but they also where our bodies meet and co-evolve with the microbial world.. Several of our studies have focused on the epithelial junctions as a target for bacterial pathogens. The host epithelium uses its epithelial junctions to form a tight but dynamic barrier with an external surface that is inhospitable to microbial attachment, secretes anti-microbial compounds, and has a rapid rate of self-renewal. The balance in the microbe-epithelial relationship results in silent commensalism or symbiosis; an imbalance results in diseases ranging from acute bacterial invasive disease to chronic ulcers or carcinoma.

    Our laboratory has developed novel microscopy applications such as quantitative 3D confocal microscopy, electron microscopy, time-lapse imaging, microinjection and micromanipulation to visualize the interaction of pathogens with epithelial cells in culture and in animal and human tissues. Many of out studies focus on the gastric pathogen Helicobacter pylori, but we have also expanded our investigations to include the intestinal pathogens Listeria monocytogenes and Salmonella enterica, and the skin pathogen and colonizer Staphylococcus aureus. I believe that elucidating how microbes communicate with and alter our epithelial cells at a molecular level will be important for finding novel therapeutic targets to control mucosal colonization and prevent invasive disease.

    Using this perspective, we have uncovered several novel concepts of how bacteria colonize and breach our epithelial surfaces. For example, we discovered that Helicobacter pylori target the intercellular junctions, and in particular that the virulence factor CagA affects junction assembly and cell polarity. This confers H. pylori the ability to extract nutrients and grow directly on the epithelial surface. We also found that these properties of CagA have consequences for cellular transformation of the epithelium. For instance, we showed that H. pylori affect the activity and state of epithelial stem cells in the stomach by colonizing the epithelial surface deep in the gastric glands. This gland-associated population is essential for pathological inflammation and hyperplasia in animal models, and confers significant colonization advantages to the bacteria. Our Listeria research uncovered a new mechanism and site where bacteria can breach the gastrointestinal epithelial barrier to invade. We found that Listeria find their receptor for invasion at sites of epithelial senescence, where the epithelial junctions undergo dynamic turnover. To study Salmonella and H. pylori we have developed a human organoid model to study their interactions with human gut epithelium in vitro. To study Staphylococcus aureus pathogenesis, we have developed methods to visualize infection at the scale of a single bacterial microcolony using an organoid culture system of human keratinocytes and fibroblasts that grow into a 3D skin-equivalent. We recently identified several proteins at the eptithelial junctions as host factors involved in the pathogenesis of one of Staphylococcus aureus major toxins.

  • Helen M. Blau

    Helen M. Blau

    Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.

  • Matthew Bogyo

    Matthew Bogyo

    Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology

    Current Research and Scholarly InterestsOur lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include:

    1) Design and synthesis of novel chemical probes for serine and cysteine hydrolases.

    2) Understanding the role of hydrolases in bacterial pathogenesis and the human parasites, Plasmodium falciparum and Toxoplasma gondii.

    3) Defining the specific functional roles of proteases during the process of tumorogenesis.

    4) In vivo imaging of protease activity

  • Paul Bollyky

    Paul Bollyky

    Associate Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly InterestsThe Bollyky Lab studies the immunology of chronic bacterial infections with an emphasis on Pseudomonas aeruginosa wound and lung infections. Our goals are to gain insight into fundamental disease mechanisms and to generate novel therapies to improve human health.

  • John  Boothroyd

    John Boothroyd

    Burt and Marion Avery Professor of Immunology

    Current Research and Scholarly InterestsWe are intereseted in the interaction between the protozoan parasite Toxoplasma gondii and its mammalian host. We use a combination of molecular and genetic tools to understand how this obligate intracellular parasite can invade almost any cell it encounters, how it co-opts a host cell once inside and how it evades the immune response to produce a life-long, persistent infection.

  • Jan Carette

    Jan Carette

    Associate Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsOur research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use haploid genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it may also facilitate the development of new therapeutic strategies.

  • Yueh-hsiu Chien

    Yueh-hsiu Chien

    Professor of Microbiology & Immunology

    Current Research and Scholarly InterestsContribution of T cells to immunocompetence and autoimmunity; how the immune system clears infection, avoids autoimmunity and how infection impacts on the development of immune responses.

  • Wah Chiu

    Wah Chiu

    Wallenberg-Bienenstock Professor and Professor of Bioengineering and of Microbiology and Immunology

    Current Research and Scholarly InterestsMy research includes methodology improvements in single particle cryo-EM for atomic resolution structure determination of molecules and molecular machines, as well as in cryo-ET of cells and organelles towards subnanometer resolutions. We collaborate with many researchers around the country and outside the USA on understanding biological processes such as protein folding, virus assembly and disassembly, pathogen-host interactions, signal transduction, and transport across cytosol and membranes.

  • Mark M. Davis

    Mark M. Davis

    Director, Stanford Institute for Immunity, Transplantation and Infection and the Burt and Marion Avery Family Professor

    Current Research and Scholarly InterestsMolecular mechanisms of lymphocyte recognition and differentiation; Systems immunology and human immunology; vaccination and infection.

  • Dylan Dodd

    Dylan Dodd

    Assistant Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsHarnessing the gut microbiome to treat human disease.

  • Elizabeth Egan

    Elizabeth Egan

    Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly InterestsMalaria is a parasitic disease transmitted by mosquitos that is a leading cause of childhood mortality globally. Public health efforts to control malaria have historically been hampered by the rapid development of drug resistance. The goal of our research is to understand the molecular determinants of critical host-pathogen interactions in malaria, with a focus on the erythrocyte host cell. Our long-term goal is to develop novel approaches to prevent or treat malaria and improve child health.

  • Shirit Einav

    Shirit Einav

    Associate Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly InterestsOur basic research program focuses on understanding the roles of virus-host interactions in viral infection and disease pathogenesis via molecular and systems virology single cell approaches. This program is combined with translational efforts to apply this knowledge for the development of broad-spectrum host-centered antiviral approaches to combat emerging viral infections, including dengue, coronaviruses, encephalitic alphaviruses, and Ebola, and means to predict progression to severe disease.

  • Michael Fischbach

    Michael Fischbach

    Associate Professor of Bioengineering and of Medicine (Microbiology and Immunology)

    BioMichael Fischbach is an Associate Professor in the Departments of Bioengineering and Microbiology & Immunology at Stanford University, an Institute Scholar of Stanford ChEM-H, and the director of the Stanford Microbiome Therapies Initiative. Fischbach is a recipient of the NIH Director's Pioneer and New Innovator Awards, an HHMI-Simons Faculty Scholars Award, a Fellowship for Science and Engineering from the David and Lucille Packard Foundation, a Medical Research Award from the W.M. Keck Foundation, a Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease award, and a Glenn Award for Research in Biological Mechanisms of Aging. His laboratory uses a combination of genomics and chemistry to identify and characterize small molecules from microbes, with an emphasis on the human microbiome. Fischbach received his Ph.D. as a John and Fannie Hertz Foundation Fellow in chemistry from Harvard in 2007, where he studied the role of iron acquisition in bacterial pathogenesis and the biosynthesis of antibiotics. After two years as an independent fellow at Massachusetts General Hospital, Fischbach joined the faculty at UCSF, where he founded his lab before moving to Stanford in 2017. Fischbach is a co-founder and director of Federation Bio and Viralogic, a co-founder of Revolution Medicines, a member of the scientific advisory boards of NGM Biopharmaceuticals and Zymergen, and an innovation partner at The Column Group.

  • Stephen J. Galli, MD

    Stephen J. Galli, MD

    Mary Hewitt Loveless, MD, Professor in the School of Medicine and Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsThe goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease. We study both the roles of mast cells, basophils, and IgE in normal physiology and host defense, e.g., in responses to parasites and in enhancing resistance to venoms, and also their roles in pathology, e.g., anaphylaxis, food allergy, and asthma, both in mice and humans.

  • Matthias Garten

    Matthias Garten

    Assistant Professor of Microbiology and of Bioengineering

    BioMatthias Garten, Ph.D., is an assistant professor in the department of Immunology and Microbiology and the department of Bioengineering. He is a membrane biophysicist who is driven by the question of how the malaria parasite interfaces with its host-red blood cell, how we can use the unique mechanisms of the parasite to treat malaria and to re-engineer cells for biomedical applications.

    He obtained a physics master's degree from the Dresden University of Technology, Germany with a thesis in the laboratory of Dr. Petra Schwille and his Ph.D. life sciences from the University Paris Diderot, France through his work in the lab of Dr. Patricia Bassereau (Insitut Curie) investigating electrical properties of lipid membranes and protein - membrane interactions using biomimetic model systems, giant liposomes and planar lipid membranes.

    In his post-doctoral work at the National Institutes of Health, Bethesda in the laboratory of Dr. Joshua Zimmerberg, he used molecular, biophysical and quantitative approaches to research the malaria parasite. His work led to the discovery of structure-function relationships that govern the host cell – parasite interface, opening research avenues to understand how the parasite connects to and controls its host cell.

  • Jeffrey S.  Glenn, M.D., Ph.D.

    Jeffrey S. Glenn, M.D., Ph.D.

    Joseph D. Grant Professor and Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsDr. Glenn's primary interest is in molecular virology, with a strong emphasis on translating this knowledge into novel antiviral therapies. Other interests include exploitation of hepatic stem cells, engineered human liver tissues, liver cancer, and new biodefense antiviral strategies.

  • Harry B Greenberg

    Harry B Greenberg

    Joseph D. Grant Professor in the School of Medicine and Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsMolecular mechanisms of pathogenesis; determinants of protective immunity; host range and tissue tropism in liver and GI tract pathogenic viruses and studies of vaccines in people.

  • Michael R. Howitt

    Michael R. Howitt

    Assistant Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsOur lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.

  • KC Huang

    KC Huang

    Professor of Bioengineering and of Microbiology and Immunology

    Current Research and Scholarly InterestsHow do cells determine their shape and grow?
    How do molecules inside cells get to the right place at the right time?

    Our group tries to answer these questions using a systems biology approach, in which we integrate interacting networks of protein and lipids with the physical forces determined by the spatial geometry of the cell. We use theoretical and computational techniques to make predictions that we can verify experimentally using synthetic, chemical, or genetic perturbations.

  • Juliana Idoyaga

    Juliana Idoyaga

    Assistant Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsThe Idoyaga Lab is focused on the function and biology of dendritic cells, which are specialized antigen-presenting cells that initiate and modulate our body’s immune responses. Considering their importance in orchestrating the quality and quantity of immune responses, dendritic cells are an indisputable target for vaccines and therapies.

    Dendritic cells are not one cell type, but a network of cells comprised of many subsets or subpopulations with distinct developmental pathways and tissue localization. It is becoming apparent that each dendritic cell subset is different in its capacity to induce and modulate specific types of immune responses; however, there is still a lack of resolution and deep understanding of dendritic cell subset functional specialization. This gap in knowledge is an impediment for the rational design of immune interventions. Our research program focuses on advancing our understanding of mouse and human dendritic cell subsets, revealing their endowed capacity to induce distinct types of immune responses, and designing novel strategies to exploit them for vaccines and therapies.

  • Peter K.  Jackson

    Peter K.  Jackson

    Professor of Microbiology and Immunology (Baxter Labs) and of Pathology

    Current Research and Scholarly InterestsCell cycle and cyclin control of DNA replication .

  • Prasanna Jagannathan

    Prasanna Jagannathan

    Assistant Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology

    BioI am an Infectious Diseases specialist with a research program in human immunology focused on malaria-specific immune responses in pregnancy and infancy. My current research program is to further our understanding of the mechanisms of clinical immunity to malaria through field-based studies, and to better understand the immunologic consequences of malaria control interventions.

    Given the profound global impact of the COVID-19 pandemic, we are also testing novel immune modulating therapeutics for the treatment of SARS-CoV-2 infected patients with mild infection (NCT 04331899). In this study 120 SARS-CoV-2 infected patients (both symptomatic and asymptomatic) are being randomized to receive Lambda vs. placebo to test the hypothesis that SARS-CoV-2-infected individuals given Lambda at the time of diagnosis have a shortened duration of viral shedding in comparison to patients given placebo. I serve as as the co-PI of this study along with Dr. Upi Singh at Stanford.

  • Karla Kirkegaard

    Karla Kirkegaard

    Violetta L. Horton Professor and Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsThe biochemistry of RNA-dependent RNA polymerase function, the cell biology of the membrane rearrangements induced by positive-strand RNA virus infection of human cells, and the genetics of RNA viruses, which, with their high error rates, live at the brink of error catastrophe, are investigated in the Kirkegaard laboratory.

  • Holden Maecker

    Holden Maecker

    Professor (Research) of Microbiology and Immunology

    Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.

  • AC Matin

    AC Matin

    Professor of Microbiology and Immunology, Emeritus

    Current Research and Scholarly Interests1. Improvement of our newly discovered cancer prodrug regimen that permits noninvaisve visualization of drug activation. 2. Tracking tumors & cancer metastases using bacterial magnetite and newly developed single-cell tracking by MRI. 3. Molecular basis of bacterial planktonic and biofilm antibiotic resistance on Earth and under space microgravity -- development of new countermeasures; 4. Bioremediation.

  • Edward Mocarski

    Edward Mocarski

    Professor of Microbiology and Immunology, Emeritus

    Current Research and Scholarly InterestsMy research interests focus on the biology and pathogenesis of cytomegalovirus (CMV), an opportunistic pathogen that causes significant disease worldwide. We developed global approaches and produced key insights into the areas of CMV gene regulation, DNA replication and packaging, maturation, impact on the host cell, disease pathogenesis, latency and reactivation, host cell signaling and chemokine system. (NOTE: Research occurs at my Emory University Vaccine Center laboratory in Atlanta, GA)

  • Denise M. Monack

    Denise M. Monack

    Martha Meier Weiland Professor in the School of Medicine

    Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.

  • Peter Parham

    Peter Parham

    Professor of Structural Biology and of Microbiology and Immunology
    On Leave from 03/01/2022 To 12/15/2022

    Current Research and Scholarly InterestsThe Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors.

  • Philip A. Pizzo, M.D.

    Philip A. Pizzo, M.D.

    David and Susan Heckerman Professor and Professor of Microbiology and Immunology

    BioPhilip Pizzo, MD, is the David and Susan Heckerman Professor and Founding Director of the Stanford Distinguished Careers Institute. Pizzo served as Dean of the Stanford School of Medicine from April 2001 to December 1, 2012, where he was also the Carl and Elizabeth Naumann Professor of Pediatrics and of Microbiology and Immunology. Dr. Pizzo has devoted much of his distinguished medical career to the diagnosis, management, prevention and treatment of childhood cancers and the infectious complications that occur in children whose immune systems are compromised by cancer and AIDS. He has also been a leader in academic medicine, championing programs and policies to improve the future of science, education and healthcare in the US and beyond.
    Pizzo received his MD degree with Honors and Distinction in Research from the University of Rochester in 1970, and completed an internship and residency at Children’s Hospital Medical Center in Boston, a teaching fellowship at Harvard Medical School, and a clinical and research fellowship in pediatric oncology at the National Cancer Institute. Pizzo served as head of the Institute’s infectious disease section, chief of the NCI’s pediatric department, and acting scientific director for NCI’s Division of Clinical Sciences between 1973 and 1996. Before joining Stanford in 2001, he was the physician-in-chief of Children’s Hospital in Boston and Chair of the Department of Pediatrics at Harvard Medical School, where he was also the Thomas Morgan Rotch Professor of Pediatrics.
    Dr. Pizzo is the author of more than 615 scientific articles and 16 books and monographs, including Principles and Practice of Pediatric Oncology, the Seventh Edition of which was published in 2015.
    Pizzo has received numerous awards and honors, among them the Public Health Service Outstanding Service Medal in 1995, the Barbara Bohen Pfiefer Award for Scientific Excellence in 1991, the Elizabeth Kubler-Ross Award in 2008, the Ronald McDonald Charities “Award of Excellence” in 2009, and the John and Emma Bonica Public Service Award in 2013. He is the 2012 recipient of the John Howland Award, the highest honor for lifetime achievement bestowed by the American Pediatric Society. He has been elected to a number of prestigious organizations and societies, including the Association of American Physicians, the American Society of Clinical Investigation, the American Pediatric Society and the Institute of Medicine of the National Academy of Sciences, where he was also elected to the Governing Council. The IOM became the National Academy of Medicine in 2015. He has served as Chair of the Association of Academic Health Centers and Chair of the Council of Deans of the Association of American Medical Colleges, and was elected to the Board of Directors of the American Society for Clinical Oncology and the Infectious Diseases Society of America. He was President of the International Immunocompromised Host Society (1998-2011). He served on the Governing Board for the California Institute of Regenerative Medicine from 2004-2012. In 2009 he was elected to the Board of Trustees of the University of Rochester and the Board of Overseers of Koc University in Istanbul, Turkey. He was a member of the Board of Directors of MRI Interventions (2013-2017) and the Academic Advisory Council for Merritt Hawkins (2015-present). In 2014 he was elected to the Board of Directors of the Ludwig Institute for Cancer Research and in 2015 he was elected to the Board of Directors of Global Blood Therapeutics. He also serves as Editor-in-Chief of Current Opinion in Pediatrics.

  • Charles G. Prober, MD

    Charles G. Prober, MD

    Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly InterestsMy research interest is in the epidemiology, pathophysiology, prevention, and treatment of infections in children. Much of this research has focused on viral infections, especially those caused by herpes simplex virus (HSV). I have conducted a number of studies concerned with the epidemiology of HSV-2 infections in pregnant women, their partners, and neonates.

  • David A. Relman

    David A. Relman

    Thomas C. and Joan M. Merigan Professor and Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsMy investigative program focuses on human-microbe interactions and human microbial ecology, and primarily concerns the ecology of human indigenous microbial communities; a secondary interest concerns the classification of humans with systemic infectious diseases, based on features of genome-wide gene transcript abundance patterns and pther aspects of the host response.

  • Peter Sarnow

    Peter Sarnow

    Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsOur laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.

  • David Schneider

    David Schneider

    Professor of Microbiology and Immunology
    On Partial Leave from 04/01/2022 To 03/01/2023

    Current Research and Scholarly InterestsWe study innate immunity and microbial pathogenesis. We have been studying models for a variety of bacterial infections including: Listeria, Mycobacteria, Salmonella and Streptococcus as well as some fungi, malaria and viruses. Our current focus is to determine how we recover from infections.

  • Robert Siegel

    Robert Siegel

    Professor (Teaching) of Microbiology and Immunology

    Current Research and Scholarly InterestsMy work is primarily involved in medical education and curricular development, especially in the areas of infectious disease, virology, HIV, and molecular biology. Projects included electronic applications to science education, three dimensional model building, service learning, and the development of undergraduate research projects.

  • Upinder Singh

    Upinder Singh

    Professor of Medicine (Infectious Diseases & Geographic Medicine) and of Microbiology and Immunology

    Current Research and Scholarly InterestsOur lab elucidates the molecular basis of pathogenesis of the protozoan parasite Entamoeba histolytica. We use genetic and genomic approaches to identify novel virulence determinants and to characterize the global epidemiology of the parasite.

  • Justin L. Sonnenburg

    Justin L. Sonnenburg

    Associate Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsThe goals of the Sonnenburg Lab research program are to (i) elucidate the basic mechanisms that underlie dynamics within the gut microbiota and (ii) devise and implement strategies to prevent and treat disease in humans via the gut microbiota. We investigate the principles that govern gut microbial community function and interaction with the host using a broad range of experimental approaches including studies of microbiomes in diverse human cohorts.

  • Lucy Tompkins

    Lucy Tompkins

    Lucy Becker Professor of Medicine and Professor of Microbiology and Immunology

    Current Research and Scholarly InterestsGenetic and cellular basis of pathogenicity of Helicobacter pylori. Molecular epidemiology, hospital epidemiology, quality improvement in healthcare associated infections.

  • Taia T. Wang, MD, PhD, MSCI

    Taia T. Wang, MD, PhD, MSCI

    Assistant Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology

    Current Research and Scholarly InterestsLaboratory of Mechanisms in Human Immunity and Disease Pathogenesis

    Studies in our lab are aimed at defining mechanisms in human immunity and disease. We are particularly interested the hypothesis that diversity in antibody-based signaling that arises from diversity in IgG antibodies and their receptors, is a central driver of heterogeneity in human immune functioning and susceptibility to infectious diseases. We are studying how the Fc domain repertoire of an individual impacts the quality of effector cell responses that can be recruited during immune activation and how selectivity of effector responses contributes to immunity and disease.

    SARS-CoV-2, dengue viruses, influenza viruses, disease pathogenesis, influenza vaccines

    Current clinical studies:
    Recruiting:

    An Open Label Study of IgG Fc Glycan Composition in Human Immunity
    Principal Investigator: Taia T. Wang, MD, PhD
    ClinicalTrials.gov Identifier:
    NCT01967238

  • Ellen Yeh

    Ellen Yeh

    Associate Professor of Pathology and of Microbiology and Immunology

    Current Research and Scholarly InterestsThe chemistry and biology of the unusual plastid organelle, the apicoplast, in malaria parasites