School of Medicine
Showing 261-280 of 284 Results
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Sui Wang, PhD
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsOur research focuses on unraveling the molecular mechanisms underlying retinal development and diseases. We employ genetic and genomic tools to explore how various retinal cell types, including neurons, glia, and the vasculature, respond to developmental cues and disease insults at the epigenomic and transcriptional levels. In addition, we investigate their interactions and collective contributions to maintain retinal integrity.
1. Investigating retinal development:
We utilize genetic tools and methods such as in vivo plasmid electroporation and CRISPR to dissect the roles of cis-regulatory elements and transcription factors in controlling retinal development.
2. Understanding diabetes-induced cell-type-specific responses in the retina:
Diabetes triggers a range of multicellular responses in the retina, such as vascular lesions, glial dysfunction, and neurodegeneration, all of which contribute to retinopathy. We delve into the detailed molecular mechanisms underlying these diabetes-induced cell-type-specific responses and the pathogenesis of diabetic retinopathy.
3. Developing molecular tools for labeling and manipulation of specific cell types in vivo:
Cis-regulatory elements, particularly enhancers, play pivotal roles in directing tissue- and cell-type-specific expression. Our interest lies in identifying enhancers that can drive cell type-specific expression in the retina and brain. We incorporate these enhancers into plasmid or AAV-based delivery systems, enabling precise labeling and manipulation of specific cell types in vivo. -
Rain Runxia Wen
Postdoctoral Scholar, Ophthalmology
BioRain Runxia Wen obtained her B.Sc. (Hons) in biology in 2012, and her Ph.D. degree in cell and developmental biology in 2018. She joined the Goldberg Lab in the Department of Ophthalmology at Stanford University in 2019. She is currently developing epigenetic tools to promote neuroregeneration, especially retinal ganglion cell, and optic nerve regeneration.
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Albert Y. Wu, MD, PhD, FACS
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsMy translational research focuses on using autologous stem cells to recreate a patient’s ocular tissues for potential transplantation. We are generating tissue from induced pluripotent stem cells to treat limbal stem cell deficiency in patients who are bilaterally blind. By applying my background in molecular and cellular biology, stem cell biology, oculoplastic surgery, I hope to make regenerative medicine a reality for those suffering from orbital and ocular disease.
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Ming Yang
Postdoctoral Scholar, Ophthalmology
BioMing YANG, MD, PhD is a postdoctoral scholar in Dr. Yang Hu’s lab at the Department of Ophthalmology at Stanford University School of Medicine. His current research interests include neuroprotection- and neuroregeneration-related mechanisms in retinal diseases including glaucoma and retinal degeneration. Dr. Yang received his MD at Shandong First Medical University & Shandong Academy of Medical Sciences in China and completed her internship at Shanghai Jiao Tong University Affiliated Sixth People's Hospital East. His long-term research interest is to find effective therapeutic targets for retinal degeneration diseases. His further goal is to be a global leading physician-scientist and to translate new treatment strategies into patient care. Some of his hobbies are hiking, reading, and swimming.
Google Scholar Citations:
https://scholar.google.com/citations?hl=en&tzom=420&user=ml8wtk4AAAAJ&authuser=4 -
Shuai Yang
Postdoctoral Scholar, Ophthalmology
BioDr. Yang obtained doctorate degree in Ophthalmology at 2017 in Tongji University, Shanghai, China. Afterwards, He works as an eye doctor in Shanghai Tenth People's Hospital. His clinial and experimantal interest is retinal disease. In June 2023, he joined Prof. Hartnett's lab to conduct postdoctoral research in neovascularization-related retinal diseases.
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Charles Yu MD
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsCorneal opacity is a leading cause of blindness. Cornea transplantation is at high risk of rejection when there is pre-existing vascularization of the cornea and in pediatric patients. Cornea transplant shortage remains a worldwide problem with millions on waitlists. Our laboratory is developing multiple strategies for treatment of corneal blindness. We are testing advanced materials and designs for keratoprostheses with the goal of reducing complications and easing surgical implantation. We are also developing intraocular electronic display prostheses for bypassing cornea opacity, a novel strategy that could allow for high quality vision without corneal clarity.
