School of Medicine


Showing 11-20 of 522 Results

  • Martin S. Angst

    Martin S. Angst

    Professor of Anesthesiology, Perioperative and Pain Medicine

    Current Research and Scholarly InterestsOur laboratory studies biological and clinical determinants of human resilience using surgery as an injury model.

  • Justin P. Annes M.D., Ph.D.

    Justin P. Annes M.D., Ph.D.

    Associate Professor of Medicine (Endocrinology)
    On Partial Leave from 05/01/2024 To 08/31/2024

    Current Research and Scholarly InterestsThe ANNES LABORATORY of Molecular Endocrinology: Leveraging Chemical Biology to Treat Endocrine Disorders

    DIABETES
    The prevalence of diabetes is increasing at a staggering rate. By the year 2050 an astounding 25% of Americans will be diabetic. The goal of my research is to uncover therapeutic strategies to stymie the ensuing diabetes epidemic. To achieve this goal we have developed a variety of innovate experimental approaches to uncover novel approaches to curing diabetes.

    (1) Beta-Cell Regeneration: Diabetes results from either an absolute or relative deficiency in insulin production. Our therapeutic strategy is to stimulate the regeneration of insulin-producing beta-cells to enhance an individual’s insulin secretion capacity. We have developed a unique high-throughput chemical screening platform which we use to identify small molecules that promote beta-cell growth. This work has led to the identification of key molecular pathways (therapeutic targets) and candidate drugs that promote the growth and regeneration of islet beta-cells. Our goal is to utilize these discoveries to treat and prevent diabetes.

    (2) The Metabolic Syndrome: A major cause of the diabetes epidemic is the rise in obesity which leads to a cluster of diabetes- and cardiovascular disease-related metabolic abnormalities that shorten life expectancy. These physiologic aberrations are collectively termed the Metabolic Syndrome (MS). My laboratory has developed an original in vivo screening platform t to identify novel hormones that influence the behaviors (excess caloric consumption, deficient exercise and disrupted sleep-wake cycles) and the metabolic abnormalities caused by obesity. We aim to manipulate these hormone levels to prevent the development and detrimental consequences of the MS.

    HEREDIATY PARAGAGLIOMA SYNDROME
    The Hereditary Paraganglioma Syndrome (hPGL) is a rare genetic cancer syndrome that is most commonly caused by a defect in mitochondrial metabolism. Our goal is to understand how altered cellular metabolism leads to the development of cancer. Although hPGL is uncommon, it serves as an excellent model for the abnormal metabolic behavior displayed by nearly all cancers. Our goal is to develop novel therapeutic strategies that target the abnormal behavior of cancer cells. In the laboratory we have developed hPGL mouse models and use high throughput chemical screening to identify the therapeutic susceptibilities that result from the abnormal metabolic behavior of cancer cells.

    As a physician scientist trained in clinical genetics I have developed expertise in hereditary endocrine disorders and devoted my efforts to treating families affected by the hPGL syndrome. By leveraging our laboratory expertise in the hPGL syndrome, our care for individuals who have inherited the hPGL syndrome is at the forefront of medicine. Our goal is to translate our laboratory discoveries to the treatment of affected families.

  • Eric Appel

    Eric Appel

    Associate Professor of Materials Science and Engineering, Senior Fellow at the Woods Institute for the Environment and Associate Professor, by courtesy, of Pediatrics (Endocrinology)

    Current Research and Scholarly InterestsThe underlying theme of the Appel Lab at Stanford University integrates concepts and approaches from supramolecular chemistry, natural/synthetic materials, and biology. We aim to develop supramolecular biomaterials that exploit a diverse design toolbox and take advantage of the beautiful synergism between physical properties, aesthetics, and low energy consumption typical of natural systems. Our vision is to use these materials to solve fundamental biological questions and to engineer advanced healthcare solutions.

  • Amin Arbabian

    Amin Arbabian

    Associate Professor of Electrical Engineering

    Current Research and Scholarly InterestsMy group's research covers RF circuits and system design for (1) biomedical, (2) sensing, and (3) Internet of Things (IoT) applications.

  • Shipra Arya

    Shipra Arya

    Professor of Surgery (Vascular Surgery)

    BioShipra Arya, MD SM FACS is a Professor of Surgery at the Stanford University School of Medicine and section chief of vascular surgery at VA Palo Alto Healthcare System. She has a Master’s degree in epidemiology from the Harvard School of Public Health with focus on research methodology and cardiovascular epidemiology. She completed her General Surgery Residency at Creighton University Medical Center followed by a Vascular Surgery Fellowship at University of Michigan. She has been funded by American Heart Association (AHA), NIH/NIA GEMSSTAR grant, VA Palo Alto Center for Innovation and Implementation (Ci2i), and is currently funded by VA HSR&D for a multicenter stepped wedge cluster randomized clinical trial called “PAtient-centered mUltidiSciplinary Care for vEterans Undergoing Surgery (PAUSE) trial”. Her current work focuses on streamlining frailty evaluation, as well as implementation of patient and system level interventions to improve surgical quality and to provide high-value and patient centered care.

    She has multiple administrative roles in surgical quality improvement as Director of Surgical Quality at VAPAHCS; Center director for Stanford University in the Vascular Quality Initiative (VQI); and the Associate Medical Director of the Northern California region for VQI, which is the national registry database and patient safety organization for Society for Vascular Surgery (SVS). Her involvement in SVS VQI also extends to being a member of the steering committee of the Vascular Implant Surveillance and Interventional Outcomes Network (VISION) to improve the quality, safety and effectiveness of vascular care. She also serves as the President of the Surgical Outcomes Club, a national organization of surgical health services researchers, and chairs multiple national committees: VA surgeons committee for the SVS and Diversity and Inclusion Committee for the Association of VA surgeons.

  • Euan A. Ashley

    Euan A. Ashley

    Associate Dean, School of Medicine, Roger and Joelle Burnell Professor of Genomics and Precision Health, Professor of Medicine (Cardiovascular Medicine), of Genetics, of Biomedical Data Science and, by courtesy, of Pathology

    Current Research and Scholarly InterestsThe Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.

  • Ritu Asija

    Ritu Asija

    Clinical Professor, Pediatrics - Cardiology

    BioI specialize in providing cardiac critical care to infants, children and adults with congenital heart disease and heart failure. I am the Associate Director for the Pulmonary Artery Reconstruction Program at Stanford, helping to coordinate comprehensive multidisciplinary care for children with severe pulmonary artery abnormalities and right ventricular dysfunction. I was a Faculty Fellow at the Stanford Center for Biodesign in 2019-2020 and continue to work on development of new technologies for the unmet needs of pediatric patients. I have an interest in physician wellness and completed the Wellness Director course through the WellMD Center at Stanford.

  • Themistocles (Tim) Assimes

    Themistocles (Tim) Assimes

    Associate Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Epidemiology and Population Health

    Current Research and Scholarly InterestsGenetic Epidemiology, Genetic Determinants of Complex Traits related to Cardiovasular Medicine, Coronary Artery Disease related pathway analyses and integrative genomics, Mendelian randomization studies, risk prediction for major adverse cardiovascular events, cardiovascular medicine related pharmacogenomics, ethnic differences in the determinants of Insulin Mediated Glucose Uptake, pharmacoepidemiology of cardiovascular drugs & outcomes

  • Jennifer Avise, MD

    Jennifer Avise, MD

    Member, Cardiovascular Institute

    BioDr. Avise is a board-certified vascular surgeon specializing in cutting edge treatments of vascular disease. She is a clinical assistant professor in the Department Surgery, Division of Vascular Surgery at Stanford University School of Medicine.

    She has helped to expand access to expert vascular surgery in the East Bay, establishing Stanford Health Care’s first vascular surgery practices at the medical center in Emeryville and at the Stanford Health Care – ValleyCare hospital in Pleasanton. Dr. Avise serves as the medical director of the Pleasanton vascular laboratory, an IAC accredited facility, where she advances developments in noninvasive testing to aid in early diagnosis of vascular disease.

    Her focus is on early detection and disease prevention, minimally invasive (endovascular) techniques, and complex open surgery. She treats a wide variety of conditions, including aortic aneurysm, limb salvage, varicose veins, peripheral vascular disease, carotid disease, complex wound care, and dialysis access.

  • David M. Axelrod, MD

    David M. Axelrod, MD

    Clinical Professor, Pediatrics - Cardiology

    Current Research and Scholarly InterestsVirtual Reality Congenital Heart Disease experience: The Stanford Virtual Heart. Currently engaged with 19 academic medical centers across the globe using our Stanford Virtual Heart to educate students and trainees, and research our VR experience as a means for training and education. Also developing next generation modeling and image interaction with Stanford engineers and educators, to promote personalized surgical training in VR and advanced educational programs in congenital heart disease.