School of Medicine
Showing 61-74 of 74 Results
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Han Sun
Postdoctoral Scholar, Genetics
Biostatistician 2, Pediatrics - EndocrinologyBioHan had been a postdoc with Dr. Steinmetz at the genetics department for five years, working on both cancers and heart diseases, trying to understand the mechanisms linking from variants to disease phenotypes. This led to a few very interesting findings of aberrant splicing regulation, such as splicing-mediated readthrough stabilization (SRS), one more mechanism for oncogene activation in multiple types of cancers, and tissue-specific splicing of a mitochondrial inner membrane protein, suggesting a molecular connection between deficiency in energy-supplying and dilated cardiomyopathy.
After being a senior computational biologist with Dr. Gloyn, who has been dedicated to the research of type 2 diabetes for decades, Han switched to the field of this multifactorial metabolic disease. It did take some courage to make such a switch at his post-postdoc stage, however, Han has a consistent interest in studying PG&E, which is not pacific gas and electric nearby, but the interaction between phenotype, genotype, and environment. With years of hands-on experience in statistical modeling and the analysis of next-generation sequencing and mass spectrometry data, in addition to a good understanding of disease genetics, cancer biology, and systems biology, Han is highly confident that he will enjoy the adventure and contribute to our understanding of diabetes. -
Jacqueline Sunderland
Adm Assoc 3, Pediatrics - Endocrinology
Current Role at StanfordAdministrative Associate, Pediatric Endocrinology & Diabetes
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Swaraj Thaman
Life Science Research Professional, Pediatrics - Endocrinology
Current Role at StanfordLife Science Research Professional 1, Translational Genomics of Diabetes Laboratory, Department of Pediatrics - Endocrinology, School of Medicine
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Darrell Wilson
Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsMy research interests cover a number of areas in Pediatric Endocrinology and Diabetes. I am PI of the Stanford Center for the NIH-funded Type-1 Diabetes TrialNet group. TrialNet conducts clinical trials directed at preventing or delaying the onset of Type 1 diabetes. I am an investigator in DirecNet, another NIH-funded study group, which is devoted to evaluating glucose sensors and the role of technology on the management of diabetes.
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Dessi Zaharieva
Instructor, Pediatrics - Endocrinology and Diabetes
Current Research and Scholarly InterestsThe 4T (Teamwork, Targets, Technology, and Tight Control) Exercise Study focuses on addressing the attitudes & barriers to exercise for families and newly diagnosed youth with type 1 diabetes (T1D). We are currently establishing feasibility and understanding physical activity patterns and behaviours in newly diagnosed youth with T1D using wearable activity trackers. This work also involves delivering structured exercise education to families and youth with T1D over telehealth.
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Yanxian Zhang
Postdoctoral Scholar, Endocrinology and Metabolism
BioThrough my academic training and research experience, I have cultivated a strong foundation in engineering and molecular biology. My work involves integrating diverse concepts from disciplines such as chemical engineering, protein engineering, supramolecular chemistry, and biophysics to address complex biomedical challenges. As a graduate student with Dr. Jie Zheng, my research focused on both natural and synthetic macromolecules. My research involved utilizing polymer chemistry to design biocompatible multifunctional hydrogels, as well as investigating the thermodynamics of amyloid proteins associated with neurodegenerative diseases. Leveraging my expertise in thermodynamics and supramolecular chemistry, I contributed to the study of understanding protein misfolding and aggregation. I identified sequence-independent inhibitors to prevent protein misfolding and developed a rational strategy for inhibitor design, enabling cross-interaction activity and the fluorescent detection of amyloids. Driven by a strong interest in translational research, I pursued postdoctoral training here at Stanford School of Medicine. In Dr. Danny Hung-Chieh Chou's lab at Stanford University, I received comprehensive training in peptide engineering and molecular biology. I am dedicated to addressing formulation challenges for insulin with stable ultra-concentrated and ultra-fast properties, aimed at miniaturizing insulin pumps and advancing the next-generation of insulin automatic delivery systems. This work is supported by the JDRF postdoctoral fellowship. Furthermore, I am working on therapeutics development and have successfully developed an insulin derivative that acts as a full insulin receptor antagonist. This development holds promise as a candidate for treating the rare disease of hyperinsulinism. Throughout my postdoctoral training, I have gained proficiency in grant writing, public speaking, and mentoring students. These experiences have significantly strengthened my skills as an independent investigator. Looking forward, my research goal is to develop innovative strategies that support the functionality and delivery of biological therapies.