School of Medicine
Showing 51-60 of 61 Results
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Upinder Singh
Stanford Medicine Professor of Infectious Disease and Professor of Medicine (Infectious Diseases & Geographic Medicine) and of Microbiology and Immunology
Current Research and Scholarly InterestsOur lab elucidates the molecular basis of pathogenesis of the protozoan parasite Entamoeba histolytica. We use genetic and genomic approaches to identify novel virulence determinants and to characterize the global epidemiology of the parasite.
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David A. Stevens
Professor of Medicine, Emeritus
Current Research and Scholarly InterestsImmunology and chemotherapy of human fungal diseases, particularly coccidioidomycosis (Valley Fever) in California and aspergillosis, and the parasitic disease, trypanosomiasis.
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Ashley Styczynski
Adjunct Clinical Assistant Professor, Medicine - Infectious Diseases
BioAshley Styczynski, MD, MPH, is an Adjunct Clinical Assistant Professor in the Division of Infectious Diseases & Geographic Medicine and Global Health Faculty Fellow, and a Medical Officer in the International Infection and Control Program at the Centers for Disease Control and Prevention (CDC). Dr. Styczynski's research interests are in infectious disease epidemiology, global health, emerging infections, and antimicrobial resistance. She holds an MPH from Johns Hopkins Bloomberg School of Public Health and an MD from University of Illinois at Chicago. Prior to coming to Stanford for her infectious disease fellowship, she spent two years as an Epidemic Intelligence Service (EIS) Officer at the CDC. During her time as an EIS officer, Dr. Styczynski conducted outbreak investigations on Zika virus, vaccinia virus, and rabies. She is currently conducting research on antimicrobial resistance and interventions to reduce nosocomial infections within low-resource healthcare facilities.
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Aruna Subramanian
Clinical Professor, Medicine - Infectious Diseases
Current Research and Scholarly InterestsMy research and scholarly interests have focused on tailoring antimicrobial prophylaxis in specific highly immunocompromised hosts depending on their specific infectious disease risks. I am interested in developing diagnostic algorithms and treatment protocols that will improve the quality of care in transplant and oncology patients.
I also have an interest in training ID fellows in this very specialized area of patient care. To that end, we have started a new ICHS ID fellowship with a specialized curriculum and are developing supplemental educational materials to enhance this training, which can be implemented at other academic training centers. -
Lucy Tompkins
Lucy Becker Professor of Medicine and Professor, by courtesy, of Microbiology and Immunology
Current Research and Scholarly InterestsGenetic and cellular basis of pathogenicity of Helicobacter pylori. Molecular epidemiology, hospital epidemiology, quality improvement in healthcare associated infections.
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Elena Vendrame
Adjunct Clinical Assistant Professor, Medicine - Infectious Diseases
Current Research and Scholarly InterestsMy research focuses on understanding the host-pathogen interactions. In particular I study the interaction between natural killer cells and HIV.
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Taia T. Wang, MD, PhD, MSCI
Assistant Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsLaboratory of Mechanisms in Human Immunity and Disease Pathogenesis
Antibodies are a critical component of host defense. While the importance of humoral immunity has been recognized for decades, substantial gaps in knowledge remain around how antibodies function, and how their function is regulated, in vivo. Our laboratory performs studies designed to fill in these gaps, with the goal of enabling new vaccine and therapeutic strategies to prevent human disease. My interest in this area culminated from training in medicine, RNA virus biology (PhD), and molecular antibody biology (postdoctoral training). The intersection of these topics, viral immunity and disease pathogenesis, is the focus of our work. The essential question driving our research is why a small subset of people develop severe or fatal disease during viral infection while most infections result in a subclinical or mild outcome, even in at-risk populations. Our hypothesis is that the antibody signaling pathways that are engaged during viral infection through Fc gamma receptors (FcγRs) are a key driver of these distinct outcomes. We are focused on several major unknowns to address this hypothesis: How are antibody effector functions regulated in vivo and does this change in disease? How do distinct signaling pathways engaged by IgG immune complex-FcγR interactions impact host cell genetic regulation and the ultimate inflammatory/immune response? What are the tissue-specific functions that antibodies engage? How does the heterogeneity in post-translational modifications (PTMs) of human antibodies contribute to heterogeneity in viral immunity?
Current clinical studies:
Recruiting:
An Open Label Study of IgG Fc Glycan Composition in Human Immunity
Principal Investigator: Taia T. Wang, MD, PhD
ClinicalTrials.gov Identifier:
NCT01967238
