Stanford University
Showing 1-20 of 836 Results
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Raya Saab
Lindhard Family Professor of Pediatric Cancer Biology
BioOur laboratory focuses on investigating molecular mechanisms of oncogene-induced tumorigenesis and tumor suppressor pathways, and oncogenic signaling in the pediatric solid tumor rhabdomyosarcoma. Our earlier work identified the tumor suppressors p53 and p18Ink4c as inhibitors of Cyclin D1-driven tumorigenesis in a pineoblastoma model, through senescence induction, and highlighted distinct roles for the the RB and p53 pathways in induction and maintenance of oncogene-induced senescence. We also identified CDK2 as a potential target for inducing senescence in premalignant lesions to inhibit tumor progression.
Our current focus is on studying oncogenic signaling and tumor suppression in the childhood tumor rhabdomyosarcoma, to identify key mediators of invasion and metastasis, which is the most common cause of treatment failure clinically. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of disease.
We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling.
Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting. -
Santiago Saavedra Pineda
Course Asst.
Biohttps://sites.google.com/view/santiago-saavedra/home
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Chiara Sabatti
Professor of Biomedical Data Science and of Statistics
Current Research and Scholarly InterestsStatistical models and reasoning are key to our understanding of the genetic basis of human traits. Modern high-throughput technology presents us with new opportunities and challenges. We develop statistical approaches for high dimensional data in the attempt of improving our understanding of the molecular basis of health related traits.
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Amin Saberi
Professor of Management Science and Engineering
BioAmin Saberi is Professor of Management Science and Engineering at Stanford University. He received his B.Sc. from Sharif University of Technology and his Ph.D. from Georgia Institute of Technology in Computer Science. His research interests include algorithms, design and analysis of social networks, and applications. He is a recipient of the Terman Fellowship, Alfred Sloan Fellowship and several best paper awards.
Amin was the founding CEO and chairman of NovoEd Inc., a social learning environment designed in his research lab and used by universities such as Stanford as well as non-profit and for-profit institutions for offering courses to hundreds of thousands of learners around the world. -
Jeremy Sabol
SLE Associate Director
BioJeremy Sabol is the Associate Director of Stanford's Program in Structured Liberal Education (SLE), where he has taught as a Lecturer since 2003. Jeremy majored in physics and literature as an undergraduate, then received his Ph.D. in French. His dissertation examined the conceptual role of fiction in Descartes' physics and philosophy, as well as the impact of this use of fiction in later 17th-century French literary texts. Jeremy specializes in early modern European thought and French existentialism. Jeremy also teaches the history & ethics of design at Stanford's d.school, and he has lectured for Stanford's Master of Liberal Arts program since 2012.
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Suzanne Michelle Sachsman, MD
Clinical Assistant Professor, Dermatology
Clinical Assistant Professor, DermatologyBioSuzanne Sachsman, M.D., is Clinical Assistant Professor of Dermatology. Dr. Sachsman received her Bachelor of Science degree in engineering from Brown University in 2000. She received her medical degree from the Keck School of Medicine of the University of Southern California in 2008 where she spent one year doing dedicated basic science research studying cancer immunotherapy. She trained in radiation oncology, completing residency at USC and fellowship at the University of Florida Health Proton Therapy Institute, prior to completing her dermatology residency at the University of California, Los Angeles in 2018. Dr. Sachsman is a board certified dermatologist and Fellow of the American Academy of Dermatology. Her clinical interests are general dermatology and complex medical dermatology including acne, psoriasis, atopic dermatitis, high risk non-melanoma skin cancer, pigmented lesions, supportive dermato-oncology, and cutaneous lymphoma.
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Zahra Sadat-Hossieny, MD
Clinical Assistant Professor, Neurology & Neurological Sciences
BioZahra Sadat-Hossieny, MD, is a board-certified neurologist who completed her fellowship in clinical epilepsy at Stanford University Hospitals and Clinics. She finished her residency in neurology at the Ohio State University Wexner Medical Center. She obtained her medical degree and a certificate in global health from the George Washington University School of Medicine and Health Sciences.
She has extensive experience treating patients with epilepsy and currently provides care through the Comprehensive Epilepsy and Comprehensive Neurology Programs at Stanford Health Care. In addition to her clinical responsibilities, Dr. Sadat-Hossieny also teaches future generations of clinicians as an assistant professor at Stanford School of Medicine in the Department of Neurology, Epilepsy, and Comprehensive Neurology.
Dr. Sadat-Hossieny has authored several peer-reviewed journal articles and book chapters. She has presented her research orally and through posters at various conferences. During her fellowship at Stanford University Hospitals and Clinics, she used advanced diagnostic techniques including video-EEG monitoring, computerized brainwave mapping, diagnostic imaging, neuropsychiatric testing, and functional mapping to accurately diagnose epilepsy and conditions imitating epilepsy. She also gained expertise in the most advanced forms of epilepsy treatment including neuromodulation, epilepsy surgery and medications specific to epilepsy. Her research focused on the cognitive effects of anti-seizure medications on patients with epilepsy and their children. She has also published on the importance of nutrient supplementation on cognition in patients taking anti-seizure medications. Her collaborations include projects that assess and improve patients’ understanding of their own seizure types. -
Rebecca Saenz
Clinical Assistant Professor, Pediatrics - Immunology and Allergy
Current Research and Scholarly InterestsAllergy, Immunology, Bioengineering and Biodesign
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Samuel Ricardo Saenz
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Sam Saenz was born in the Bay Area and received his bachelor’s degree in psychology from Stanford University. He completed his medical degree at UC Irvine’s Program in Medical Education for the Latino Community, and he also obtained a Master’s in Public Health from UC Berkeley. After serving as chief psychiatry resident during his psychiatry residency at Stanford, he completed a fellowship in public psychiatry at UC San Francisco. His professional interests include fostering the next generation of diverse mental health providers as well as advancing justice, equity, and inclusion (JEDI) work in academic medicine.
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Debra Safer
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)
Current Research and Scholarly InterestsPrimary research interests include the nature and treatment of eating disorders
(particularly bulimia nervosa and binge eating disorder), the development and treatment of obesity, and the development and treatment of problematic eating patterns in patients following bariatric surgery. -
Gabriella Safran
Senior Associate Dean of Humanities and Arts, Eva Chernov Lokey Professor of Jewish Studies, Professor of Slavic Languages and Literatures and, by courtesy, of German Studies and of Comparative Literature
BioGabriella Safran has written on Russian, Polish, Yiddish, and French literatures and cultures. Her most recent monograph, Wandering Soul: The Dybbuk's Creator, S. An-sky (Harvard, 2010), is a biography of an early-twentieth-century Russian-Yiddish writer who was also an ethnographer, a revolutionary, and a wartime relief worker.
Safran teaches and writes on Russian literature, Yiddish literature, folklore, and folkloristics. She is now working on two monograph projects: one on how people in the Russian Empire listened across social lines, recorded and imitated others’ voices in various media, and reflected on listening and vocal imitation, from the 1830s to the 1880s, and the other on the international pre-history of the Jewish joke.
For more information about her activities and publications, see https://dlcl.stanford.edu/people/gabriella-safran -
Marc R. Safran, MD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Safrans practice focuses on arthroscopic management of hip problems as well as articular cartilage regeneration, shoulder surgery and athletic shoulder and elbow problems. He is actively involved in research in these areas.
