Stanford University
Showing 51-100 of 169 Results
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Bertil Glader
Stanford Medicine Professor of Pediatric Hematology/Oncology and Professor, by courtesy, of Pathology
Current Research and Scholarly InterestsHematology/Oncology, biology, and treatment of bone marrow failure disorders, hereditary coagulation disorders-clinical trials.
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Lawrence Tim Goodnough
Professor of Pathology and of Medicine (Hematology), Emeritus
Current Research and Scholarly InterestsImproving blood utilization
Promoting alternatives to blood transfusion
Quality improvements -
Dita Gratzinger
Professor of Pathology
Current Research and Scholarly InterestsI have research interests in the interaction of hematolymphoid neoplasia with the microenvironment. For example, I use a combination of immunohistochemistry, immunofluorescence and image analysis techniques to evaluate the mesenchymal stromal cell compartment in myelodysplastic syndrome (pre-leukemic bone marrow failure disorder). I also have interests in lymphoma vasculature and the tropism of lymphoma for specific types of vasculature.
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Wei Gu
Assistant Professor of Pathology
BioWei Gu, MD, PhD, is a physician, engineer, and scientist whose research focus is methylation classification within the area of molecular pathology. He has pioneered technologies in cell-free DNA 'liquid biopsy' testing, CRISPR diagnostics, clinical metagenomic sequencing, non-invasive prenatal testing, and COVID diagnostics. Dr. Gu has received awards from the Burroughs Wellcome Career Award and the National Cancer Institute. As a physician, he is a board-certified molecular and clinical pathologist and maintains a clinical practice at Stanford Healthcare.
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Michael Hendrickson
Professor of Pathology at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsDiagnosis of progressive stages of uterine cancer; classification of ovarian tumors; breast cancer diagnosis and prognostic factors, soft tissue neoplasm, uterine mesenchymal neoplasm.
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John Higgins
Professor of Pathology
Current Research and Scholarly InterestsI work as a diagnostic surgical pathologist doing translational research in renal neoplasia and medical renal disease and neoplastic and medical liver disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology.
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Jody Elizabeth Hooper
Associate Professor of Pathology
Current Research and Scholarly InterestsI am the Director of the Research Autopsy Collaboration at Stanford (RACS) to collect organs and tissues from decedent donors for cancer and disease research. https://med.stanford.edu/racs
I have a number of research interests associated with my autopsy work, including how the time interval between death and collection (the PMI) affects the condition and research viability of the collected tissue, how valuable blood and tissue cultures behave after death, and how autopsy results affect clinical practice in an established information loop. I have projects exploring physician and family attitudes towards autopsy and the utilization of rapid autopsy tissue in characterizing cancer evolution from genetic and immunologic standpoints. -
Dikran Horoupian
Professor (Clinical) of Pathology, Emeritus
Current Research and Scholarly InterestsNeuropathology of:
1. Neurodegenerative diseases
2. Neurodevelopmental disorders
3. CNS neoplasms
4. Nerve & muscle diseases -
Brooke Howitt
Associate Professor of Pathology
BioDr. Howitt is a gynecologic and sarcoma pathologist, with academic interests in gynecologic mesenchymal tumors and morphologic and clinical correlates of molecular alterations in gynecologic neoplasia.
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Michael R. Howitt
Assistant Professor of Pathology and of Microbiology and Immunology
Current Research and Scholarly InterestsOur lab is broadly interested in how intestinal microbes shape our immune system to promote both health and disease. Recently we discovered that a type of intestinal epithelial cell, called tuft cells, act as sentinels stationed along the lining of the gut. Tuft cells respond to microbes, including parasites, to initiate type 2 immunity, remodel the epithelium, and alter gut physiology. Surprisingly, these changes to the intestine rely on the same chemosensory pathway found in oral taste cells. Currently, we aim to 1) elucidate the role of specific tuft cell receptors in microbial detection. 2) To understand how protozoa and bacteria within the microbiota impact host immunity. 3) Discover how tuft cells modulate surrounding cells and tissue.
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Chris C.S. Hsiung
Instructor, Pathology
BioI am a molecular biologist and laboratory medicine physician. I am interested in understanding how cells turn genes on or off, and engineering ways we can turn genes on or off for biological discovery and therapeutic benefit.
In my postdoctoral work advised by Dr. Luke Gilbert (Arc Institute), I developed multiAsCas12a (multiplexed transcriptional interference Acidaminococcus Cas12a), a new functional genomics platform capable of higher-order combinatorial chromatin targeting of multiple coding and non-coding genetic elements per cell, including in pooled 6-plex CRISPRi screens. I proposed a group testing experimental framework to efficiently survey higher-order combinatorial spaces of genetic perturbations. I applied this approach to discover new enhancer elements and dissect the combinatorial logic of cis-regulatory elements.
In my prior work as an MD-PhD student co-advised by Dr. Arjun Raj and Dr. Gerd Blobel at the Univ. of Pennsylvania, I led several studies focused on how gene regulatory information is maintained or altered through mitosis in mammalian cells, using epigenomics methods, single-molecule RNA imaging, and computational analysis. -
Peter K. Jackson
Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Current Research and Scholarly InterestsCell cycle and cyclin control of DNA replication .
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Siddhartha Jaiswal
Assistant Professor of Pathology
Current Research and Scholarly InterestsWe identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.
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Kristin Jensen
Associate Professor of Pathology
Current Research and Scholarly InterestsI am a clinical translational investigator with a primary interest in breast cancer biology, and the use of investigational and clinical ancillary techniques such as gene and tissue microarray analysis and immunohistochemistry in the diagnosis and prognosis of this disease. As a practicing cytopathologist, I also have an interest in improving the fine needle aspiration biopsy diagnosis of breast lesions, again using immunohistochemistry and gene expression analysis as adjuncts to cytomorphology.
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Neeraja Kambham
Professor of Pathology
Current Research and Scholarly InterestsDr. Kambham's research interests primarily involve medical diseases and transplantation pathology of the kidney and liver.
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Maya M. Kasowski
Assistant Professor of Pathology, of Medicine (Pulmonary, Allergy and Critical Care Medicine) and, by courtesy, of Genetics
BioI am a clinical pathologist and assistant professor in the Departments of Medicine, Pathology, and Genetics (by courtesy) at Stanford. I completed my MD-PhD training at Yale University and my residency training and a post-doctoral fellowship in the Department of Genetics at Stanford University. My experiences as a clinical pathologist and genome scientist have made me passionate about applying cutting-edge technologies to primary patient specimens in order to characterize disease pathologies at the molecular level. The core focus of my lab is to study the mechanisms by which genetic variants influence the risk of disease through effects on intermediate molecular phenotypes.
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Christina Kong
Professor of Pathology
Current Research and Scholarly InterestsImproving the accuracy of cytologic diagnosis through the use of ancillary techniques on specimens obtained by fine needle aspiration biopsy.
Identifying potential indicators of prognosis in head and neck squamous cell carcinomas.
Evaluating the utility of immunohistochemical stains in refining the diagnosis of squamous dysplasia of the cervix, vulva, and head and neck. -
Christian Kunder
Clinical Associate Professor, Pathology
Current Research and Scholarly InterestsMy main interest is in understanding the biology of human neoplasms, using traditional histopathology, molecular genetic techniques, and other modalities. In particular, I am interested in soft tissue and genitourinary neoplasms, especially prostate cancer.
I am also interested in the classification and nomenclature of neoplasms and in practical research that helps us refine these, using a variety of techniques but still principally guided by histopathology.
I also work on developing next generation sequencing-based tests for genotyping tumors and in expanding the scope of this testing with the goal of identifying patients eligible for novel targeting therapies. -
Caleb Lareau
Instructor, Pathology
BioProfile moved to lab website: https://clareaulab.com/
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Joseph (Joe) Lipsick
Professor of Pathology and of Genetics
Current Research and Scholarly InterestsFunction and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.
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Amy Lo
Adjunct Clinical Associate Professor, Pathology
BioDr. Amy Lo is a pathologist with board certification in anatomic pathology, clinical pathology and molecular genetic pathology. She completed her MD and MS at the University of Illinois at Chicago and her residency in both anatomic and clinical pathology at Northwestern University. She then joined the faculty at Northwestern University as a Clinical Instructor and Advanced Gastrointestinal/Surgical Pathology Fellow. Amy then completed a molecular genetic pathology fellowship at Stanford University.
In 2016, Amy joined Genentech as research pathology scientist supporting drug research and development with a focus in oncology and individualized drug development.
Additionally, Amy continues clinical work as an Adjunct Clinical Associate Professor in pathology at Stanford University and Lucille Packard’s Children’s Hospital. -
Jonathan Z. Long
Associate Professor of Pathology
BioDr. Jonathan Long is an Associate Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). His laboratory studies signaling pathways in mammalian energy metabolism. The long-term goal of this program is to discover new molecules and pathways that can be translated into therapeutic opportunities for obesity, metabolic disease, and other age-associated chronic diseases. Work from the laboratory has been recognized by numerous awards from the Alfred P. Sloan Foundation, the National Institutes of Health, the American Diabetes Association, and the Ono Pharma Foundation. Prior to arriving to Stanford, Dr. Long completed his Ph.D. in Chemistry at Scripps Research and his postdoctoral work at Harvard Medical School.
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Teri A Longacre
Richard L. Kempson, MD, Professor in Surgical Pathology
Current Research and Scholarly InterestsGynecological, breast and gastrointestinal pathology with major emphasis on ovarian cancer and ovarian tumors of low malignant potential. Pathology of familial and hereditary breast-ovarian-GI cancer.
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Alarice Cheng-Yi Lowe
Associate Professor of Pathology
BioDr. Lowe joined the School of Medicine faculty in 2019. She received her undergraduate degree in Biology from MIT and her medical degree at UCSD, prior to residency and cytology fellowship at UCLA. In 2011, she joined the faculty at Brigham and Women's Hospital where she developed a research focus on Circulating Tumor Cells (CTCs) and the application of new technology to improve clinical and molecular diagnostics. Clinically, her interests focus on Cytopathology and Genitourinary Pathology.
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Bingwei Lu
Professor of Pathology
Current Research and Scholarly InterestsWe are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimers and Parkinsons diseases. We are using both Drosophila and mammalian models to address these fundamental questions.
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Ruben Y. Luo
Assistant Professor of Pathology
Current Research and Scholarly InterestsApply top-down mass spectrometry and label-free immunoassay to the study and utilization of biomarker proteoforms in clinical diagnosis.
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Magdalena Matusiak
Instructor, Pathology
Current Research and Scholarly InterestsMy research focuses on revealing clinically relevant prognostic markers associated with myeloid cell biology in solid malignancies. I currently. lead two main projects: first, using single-cell RNA Sequencing and bulk tissue genomics to discover tumor-associated macrophage (TAM) diversity and establish their prognostic and predictive markers, second: using multiplex tissue imaging (MIBI) to unravel prognostic markers of spatial heterogeneity in the colon cancer.
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Joshua Menke
Clinical Assistant Professor, Pathology
BioDr. Joshua Menke completed his hematopathology fellowship at Stanford and cytopathology fellowship at University of California San Francisco (UCSF). His clinical and research interests lie at the intersection of hematopathology, cytopathology and advanced single cell and cell free diagnostic techniques. As Associate Section Director of Clinical Flow Cytometry at Stanford, Dr. Menke is developing and validating new minimal residual disease assays for detecting low levels of myeloid and lymphoid neoplasms in the post-treatment setting as well as multiple other 12 color flow assays with the latest markers for routine phenotyping. Dr. Menke is the receipient of the Paul E. Standjord Young Investigator Award from the Academy of Clinical Laboratory Scientists and Laurance J. Marton Award for Excellence in Research from UCSF for his translational work on CALR mutations at the UCSF Molecular Diagnostics Laboroatory. Currently, he is spearheading novel genomic and proteomic analytic techniques to study cytology samples obtained for lymphoma diagnostics, including sequencing cell-free tumor DNA from supernatant samples. Dr. Menke is a founding member of the Cytology-Hematopathology Interinstitution Collaboration (CHIC) that aims to study the performance of cytology samples in diagnosing lymphoma across large datasets from five academic institutions and currently chairs that group spearheading large clinical research studies.
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Sara Michie
Professor of Pathology (Research), Emerita
Current Research and Scholarly InterestsLymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules.
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Paul Salomon Mischel
Fortinet Founders Professor and Professor, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy research bridges cancer genetics, signal transduction and cellular metabolism as we aim to understand the molecular mechanisms that drive cancer development, progression, and drug resistance. We have made a series of discoveries that have identified a central role for ecDNA (extrachromosomal DNA) in cancer development, progression, accelerated tumor evolution and drug resistance.
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Michelle Monje
Milan Gambhir Professor of Pediatric Neuro-Oncology and Professor, by courtesy, of Neurosurgery, of Pediatrics, of Pathology and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsThe Monje Lab studies the molecular and cellular mechanisms of postnatal neurodevelopment. This includes microenvironmental influences on neural precursor cell fate choice in normal neurodevelopment and in disease states.
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Stephen B. Montgomery
Stanford Medicine Professor of Pathology, Professor of Genetics and of Biomedical Data Science
On Partial Leave from 06/17/2024 To 08/15/2024Current Research and Scholarly InterestsWe focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches. See our website at http://montgomerylab.stanford.edu/
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Thomas Montine, MD, PhD
Stanford Medicine Professor of Pathology
BioDr. Montine received his education at Columbia University (BA in Chemistry), the University of Rochester (PhD in Pharmacology), and McGill University (MD and CM). His postgraduate medical training was at Duke University, and he was junior faculty at Vanderbilt University where he was awarded the Thorne Professorship in Pathology. In 2002, Dr. Montine was appointed as the Alvord Endowed Professor in Neuropathology and Director of the Division of Neuropathology at the University of Washington. He was Director of the University of Washington Alzheimer’s Disease Research Center, one of the original 10 Centers in the US, and passed that responsibility to able colleagues. Dr. Montine was the founding Director of the Pacific Udall Center, a NINDS-funded Morris K. Udall Centers of Excellence for Parkinson’s Disease Research. In 2010, Dr. Montine was appointed Chair of the Department of Pathology at the University of Washington. In 2016, Dr. Montine was appointed Chair of the Department of Pathology at Stanford University where he is the Stanford Medicine Endowed Professor in Pathology.
The focus of the Montine Laboratory is on the structural and molecular bases of cognitive impairment. The Montine Laboratory addresses this prevalent, unmet medical need through a combination of neuropathology, biomarkers for detection and progression of early disease, and experimental studies that test hypotheses concerning specific mechanisms of neuron injury and then develop novel approaches to neuroprotection. Our current approaches include small molecule precision therapeutics and cell replacement strategies for brain. -
Saisindhu Narala, MD, MAS
Clinical Assistant Professor, Dermatology
Clinical Assistant Professor, PathologyBioDr. Narala completed her dermatology residency at the University of Texas at Houston and MD Anderson Cancer Center. She then completed a fellowship in dermatopathology at Stanford. Her clinical interests include general medical dermatology, dermatology in skin of color, and pigmentary disorders. She also has an interest in medical education.
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Yasodha Natkunam, M.D., Ph.D
Ronald F. Dorfman, MBBch, FRCPath Professor of Hematopathology
Current Research and Scholarly InterestsMy research interests focus on the identification and characterization of markers of diagnostic and prognostic importance in hematolymphoid neoplasia.
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Jeff Nirschl
Instructor, Pathology
BioJeff Nirschl, M.D., Ph.D. is an Instructor in Pathology at Stanford University, Stanford, CA with clinical expertise in Neuropathology. He completed his Ph.D. in Neuroscience at the University of Pennsylvania under the supervision of Dr. Erika Holzbaur. During his thesis research, he investigated axonal transport and genetic forms of parkinsonism. He also developed computational image analysis workflows for fluorescence microscopy and digital pathology. His research interests include molecular motors and the neuronal cytoskeleton, the regulation of axonal transport in neurodegeneration, digital pathology, and quantitative image analysis using machine learning.
https://orcid.org/0000-0001-6857-341X
