Stanford University
Showing 21-30 of 45 Results
-
Keith Hodgson
David Mulvane Ehrsam and Edward Curtis Franklin Professor of Chemistry and Professor of Photon Science
BioCombining inorganic, biophysical and structural chemistry, Professor Keith Hodgson investigates how structure at molecular and macromolecular levels relates to function. Studies in the Hodgson lab have pioneered the use of synchrotron x-radiation to probe the electronic and structural environment of biomolecules. Recent efforts focus on the applications of x-ray diffraction, scattering and absorption spectroscopy to examine metalloproteins that are important in Earth’s biosphere, such as those that convert nitrogen to ammonia or methane to methanol.
Keith O. Hodgson was born in Virginia in 1947. He studied chemistry at the University of Virginia (B.S. 1969) and University of California, Berkeley (Ph.D. 1972), with a postdoctoral year at the ETH in Zurich. He joined the Stanford Chemistry Department faculty in 1973, starting up a program of fundamental research into the use of x-rays to study chemical and biological structure that made use of the unique capabilities of the Stanford Synchrotron Radiation Lightsource (SSRL). His lab carried out pioneering x-ray absorption and x-ray crystallographic studies of proteins, laying the foundation for a new field now in broad use worldwide. In the early eighties, he began development of one of the world's first synchrotron-based structural molecular biology research and user programs, centered at SSRL. He served as SSRL Director from 1998 to 2005, and SLAC National Accelerator Laboratory (SLAC) Deputy Director (2005-2007) and Associate Laboratory Director for Photon Science (2007-2011).
Today the Hodgson research group investigates how molecular structure at different organizational levels relates to biological and chemical function, using a variety of x-ray absorption, diffraction and scattering techniques. Typical of these molecular structural studies are investigations of metal ions as active sites of biomolecules. His research group develops and utilizes techniques such as x-ray absorption and emission spectroscopy (XAS and XES) to study the electronic and metrical details of a given metal ion in the biomolecule under a variety of natural conditions.
A major area of focus over many years, the active site of the enzyme nitrogenase is responsible for conversion of atmospheric di-nitrogen to ammonia. Using XAS studies at the S, Fe and Mo edge, the Hodgson group has worked to understand the electronic structure as a function of redox in this cluster. They have developed new methods to study long distances in the cluster within and outside the protein. Studies are ongoing to learn how this cluster functions during catalysis and interacts with substrates and inhibitors. Other components of the protein are also under active study.
Additional projects include the study of iron in dioxygen activation and oxidation within the binuclear iron-containing enzyme methane monooxygenase and in cytochrome oxidase. Lab members are also investigating the role of copper in electron transport and in dioxygen activation. Other studies include the electronic structure of iron-sulfur clusters in models and enzymes.
The research group is also focusing on using the next generation of x-ray light sources, the free electron laser. Such a light source, called the LCLS, is also located at SLAC. They are also developing new approaches using x-ray free electron laser radiation to image noncrystalline biomolecules and study chemical reactivity on ultrafast time scales. -
Matthias Ihme
Professor of Mechanical Engineering, of Photon Science and, by courtesy, of Energy Science and Engineering
BioLarge-eddy simulation and modeling of turbulent reacting flows, non-premixed flame, aeroacoustics and combustion generated noise, turbulence and fluid dynamics, numerical methods and high-order schemes.
-
Kent Irwin
Director, Hansen Experimental Physics Laboratory (HEPL), Professor of Physics, of Particle Physics and Astrophysics and of Photon Science
BioIrwin Group web page:
https://irwinlab.stanford.edu/ -
Thomas Jaramillo
Professor of Chemical Engineering, of Energy Science Engineering, of Photon Science and Senior Fellow at the Precourt Institute for Energy
BioRecent years have seen unprecedented motivation for the emergence of new energy technologies. Global dependence on fossil fuels, however, will persist until alternate technologies can compete economically. We must develop means to produce energy (or energy carriers) from renewable sources and then convert them to work as efficiently and cleanly as possible. Catalysis is energy conversion, and the Jaramillo laboratory focuses on fundamental catalytic processes occurring on solid-state surfaces in both the production and consumption of energy. Chemical-to-electrical and electrical-to-chemical energy conversion are at the core of the research. Nanoparticles, metals, alloys, sulfides, nitrides, carbides, phosphides, oxides, and biomimetic organo-metallic complexes comprise the toolkit of materials that can help change the energy landscape. Tailoring catalyst surfaces to fit the chemistry is our primary challenge.
-
Chi-Chang Kao
Professor of Photon Science and Senior Fellow at the Precourt Institute for Energy
BioChi-Chang Kao works on the development of experimental methods exploiting the unique properties of high-brightness storage rings and X-ray Free Electron Lasers (XFEL), and their applications to materials science. Currently, he is working on using X-ray scattering in combination with high magnetic fields to study high-temperature superconductors, inelastic X-ray scattering study of materials using XFEL, and X-ray study of materials for energy applications.
Kao served as the fifth director of the SLAC National Accelerator Laboratory from November 2012 to February 2023. Prior to that, he served at Brookhaven National Laboratory for nearly 25 years in a variety of positions, including five years as chairperson of the National Synchrotron Light Source (NSLS). He was elected a fellow of the American Physical Society in 2006 and was named a fellow of the American Association for the Advancement of Science in 2010 for his many contributions to resonant elastic and inelastic X-ray scattering techniques and their application to materials physics, as well as for his leadership at the NSLS. -
Matthias Kling
Director, PULSE Institute, Professor of Photon Science and, by courtesy, of Applied Physics
Current Research and Scholarly InterestsKling's research focuses on ultrafast electronics and nanophotonics employing ultrashort flashes of light from table-top and free-electron laser sources.
-
Aaron Lindenberg
Professor of Materials Science and Engineering and of Photon Science
BioLindenberg's research is focused on visualizing the ultrafast dynamics and atomic-scale structure of materials on femtosecond and picosecond time-scales. X-ray and electron scattering and spectroscopic techniques are combined with ultrafast optical techniques to provide a new way of taking snapshots of materials in motion. Current research is focused on the dynamics of phase transitions, ultrafast properties of nanoscale materials, and charge transport, with a focus on materials for information storage technologies, energy-related materials, and nanoscale optoelectronic devices.
