Stanford University
Showing 1,161-1,170 of 13,083 Results
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Nawal Maria Boukli
Affiliate, Neurosurgery
BioDr. Nawal Boukli’s research focuses on understanding how cells transition from adaptive to maladaptive stress responses, with a central emphasis on endoplasmic reticulum (ER) stress, unfolded protein response (UPR) signaling, and GRP78 as a master regulator of cell fate and survival. Her work has defined critical mechanistic links between GRP78-driven stress adaptation, metabolic reprogramming, and therapeutic resistance in glioblastoma (GBM), while advancing GRP78 as a translational therapeutic target through antibody-based anti-GRP78 strategies designed to disrupt tumor survival pathways.
Her broader research program integrates molecular biology, quantitative multi-omics, cancer biology, and NeuroHIV to uncover stress-driven mechanisms underlying disease progression. In parallel, her NeuroHIV studies investigate how HIV-1 gp120 induces maladaptive ER stress responses that alter astrocyte–neuron communication, promote synaptic vulnerability, and contribute to neurodegenerative processes. Collectively, her work bridges cancer and neurodegeneration through a unifying framework centered on proteostasis disruption and chronic stress signaling.
In her project at Stanford University, awarded by The NIH Brain Initiative, Dr. Boukli is extending her research program using advanced spatial omics and neurobiology approaches to define astrocyte-specific ER stress domains and map how gp120-driven stress signaling becomes spatially organized within intact neural systems. This work aims to identify spatially resolved therapeutic targets and advance high-impact translational neuroscience studies.
Dr. Boukli is also recognized for her innovative teaching, scientific leadership, and commitment to mentorship. She has mentored more than 32 master’s students, 8 Ph.D. students, and numerous undergraduate trainees, while developing student-centered scientific training and mentoring initiatives. Following her election to the Association of Biomolecular Resource Facilities Executive Board in 2019, she launched the organization’s first annual speed-mentoring initiative in 2020. She additionally serves as a reviewer for the National Institutes of Health Center for Scientific Review, including study sections focused on cancer therapeutics and biomarker development.
Selected Peer-Reviewed Publications:
https://pubmed.ncbi.nlm.nih.gov/?term=nawal+boukli&sort=pubdate -
Donna M. Bouley, DVM, PhD
Professor of Comparative Medicine at the Stanford University Medical Center, Emerita
Current Research and Scholarly InterestsResearch interests: ocular pathology, host-pathogen interactions in infectious disease, infectious disease in frogs, phenotypic characterization of tg and ko mice, histopathology of minimally-invasive radiological ablation techniques (focused ultrasound, cryoablation).
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Robert Downey Boutin
Clinical Professor, Radiology
BioDr. Boutin works clinically as a musculoskeletal radiologist interpreting a broad array of diagnostic imaging examinations, most frequently MRI, CT, sonography, and radiography.
The clinical focus for Dr. Boutin is MRI and CT of joints, bones, and muscles, as well as adding value to routine radiology exams by translating advancements from fields of artificial intelligence and imaging informatics. These advancements include enhancing routine imaging exams to help promote physical function, quality of life, and healthspan in our patients. Because the worldwide population of people > 60 years of age is projected to double by 2050, there is a crucial need for improvements in the accurate and efficient management of derangements associated with biological aging, including osteoporosis, sarcopenia, and adiposity.
Dr. Boutin was introduced to orthopaedics at an early age by his father and older brother -- both orthopaedists. After earning undergraduate and graduate degrees at Stanford University, Dr. Boutin completed advanced fellowship training in Musculoskeletal Imaging at the University of California, San Diego, and worked on the faculty at Harvard Medical School. Core professional values include a commitment to outstanding quality, compassion, safety, and integrity.
Dr. Boutin is a leader in musculoskeletal imaging. He is the President of the Society of Academic Bone Radiologists and serves on the Appropriateness Criteria Panel for the American College of Radiology. He is an Assistant Editor at the American Journal of Roentgenology (AJR), and recently served as the Chair of the Musculoskeletal Imaging Program Committee for the largest medical meeting in the world (RSNA).
He is a frequent invited lecturer for continuing medical education courses, such as those at the annual meetings of the Radiological Society of North America, the International Skeletal Society, and the American Roentgen Ray Society. He also lectures regularly at the international Orthopaedic Imaging course in Davos, Switzerland.
