Stanford University
Showing 12,741-12,750 of 12,883 Results
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Weiruo Zhang
Affiliate, Biomedical Data Science
BioDr. Zhang is currently a research engineer at the Department of Biomedical Data Science, and the data manager in the Center for Cancer Systems Biology at Stanford. Dr. Zhang completed her M.S. and Ph.D. in Electrical Engineering, both from Stanford University. Her Ph.D. studies focused on developing machine learning (ML) algorithms for metabolomics data analysis using graph theory. She received Young Scientist Award from the Metabolomics Society for her algorithm on metabolic network analysis delineating the effects of genetic mutants and drug treatment on the metabolome. Her postdoctoral studies at the Department of Radiology, Stanford School of Medicine, integrated radiomic, genomic, transcriptomic, histopathologic and clinical data that identified a prognostic metabolic regulation biomarker for non-small cell lung cancer. She has developed open-source computational tools that have been appreciated by the broad research community and industry, including the CELESTA algorithm which has been incorporated into commercial analytical platform of NanoString. Dr. Zhang's research has made significant impacts in the fields of spatial multi-omics and cancer systems biology, and she has authored and co-authored publications including Cell, Nature Methods, Nature Communications etc.
Dr. Zhang's current research at Stanford primarily focuses on developing and implementing ML/AI approaches to integrate and analyze multi-modality data, including spatial multi-omics, radiologic imaging, histopathologic images and clinical data. Her research aims at bridging the gap between underlying disease molecular/cellular biology and clinical assessment to improve diagnostics, prognostics and treatment strategies. -
Wubing Zhang
Postdoctoral Scholar, Stem Cell Biology and Regenerative Medicine
Current Research and Scholarly InterestsI'm interested in developing innovative methods and integrating multi-omics data to understand tumor-immune regulation and identify potential targets for cancer therapy.
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Yanxian Zhang
Postdoctoral Scholar, Endocrinology and Metabolism
BioThrough my academic training and research experience, I have cultivated a strong foundation in engineering and molecular biology. My work involves integrating diverse concepts from disciplines such as chemical engineering, protein engineering, supramolecular chemistry, and biophysics to address complex biomedical challenges. As a graduate student with Dr. Jie Zheng, my research focused on both natural and synthetic macromolecules. My research involved utilizing polymer chemistry to design biocompatible multifunctional hydrogels, as well as investigating the thermodynamics of amyloid proteins associated with neurodegenerative diseases. Leveraging my expertise in thermodynamics and supramolecular chemistry, I contributed to the study of understanding protein misfolding and aggregation. I identified sequence-independent inhibitors to prevent protein misfolding and developed a rational strategy for inhibitor design, enabling cross-interaction activity and the fluorescent detection of amyloids. Driven by a strong interest in translational research, I pursued postdoctoral training here at Stanford School of Medicine. In Dr. Danny Hung-Chieh Chou's lab at Stanford University, I received comprehensive training in peptide engineering and molecular biology. I am dedicated to addressing formulation challenges for insulin with stable ultra-concentrated and ultra-fast properties, aimed at miniaturizing insulin pumps and advancing the next-generation of insulin automatic delivery systems. This work is supported by the JDRF postdoctoral fellowship. Furthermore, I am working on therapeutics development and have successfully developed an insulin derivative that acts as a full insulin receptor antagonist. This development holds promise as a candidate for treating the rare disease of hyperinsulinism. Throughout my postdoctoral training, I have gained proficiency in grant writing, public speaking, and mentoring students. These experiences have significantly strengthened my skills as an independent investigator. Looking forward, my research goal is to develop innovative strategies that support the functionality and delivery of biological therapies.
