Stanford University
Showing 28,041-28,050 of 34,428 Results
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Selene Wang Sobek
Postdoctoral Scholar, Psychiatry
BioSelene’s research focuses on understanding how stress and early-life experiences shape the neural circuits involved in opioid addiction and relapse. Her previous work examined how stress-related changes in brain reward circuits can increase vulnerability to opioid seeking following abstinence. This work inspired a broader interest in how dopamine and opioid signaling interact to influence addictive behaviors. Her current research investigates how ibogaine affects the neural systems associated with opioid addiction and explores whether understanding its mechanisms could contribute to developing more effective treatments for opioid use disorder.
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Raymond A. Sobel, M.D.
Professor of Pathology
Current Research and Scholarly InterestsWe study cellular and molecular mechanisms of immune-mediated injury in CNS tissues that are affected in multiple sclerosis (MS). We study: 1) tissues of mice with EAE using histology and immunohistochemistry, 2) cross-recognition of neurons by antibodies against myelin proteolipid protein epitopes, and a distinct oligodendrogliopathy induced in mice by the non-protein amino acid azetidine (Aze), (which is found in the human diet); Aze-induced abnormalities mimic those in MS patient CNS tissues
