Vice Provost and Dean of Research
Showing 2,041-2,060 of 2,472 Results
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Laura Simons
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric)
Current Research and Scholarly InterestsI am a Professor in the Department of Anesthesiology, Perioperative, and Pain Medicine at Stanford University School of Medicine and a clinical psychologist who evaluates and treats youth presenting with chronic pain in the Pediatric Pain Management Clinic (PPMC) at Stanford Children’s Health. My program of research aims to utilize a pain neuroscience psychology approach to gain a mechanistic understanding of cognitive and affective processes in pediatric pain, perform rigorous patient-oriented research that translates targeted assessment into mechanistically informed treatment approaches for optimal clinical care and leverage the ubiquity of digital health to enhance patient access and reach. Central to these goals are projects targeting adolescence and youth adults with chronic pain that encompass defining brain signatures of threat interpretation, evaluating the efficacy of graded exposure (NCT03699007), deriving a biosignature of improvement vs. persistence of pain and disability (NCT04285112), and evaluating the impact of virtual reality on pain rehabilitation (NCT04636177). These studies along with additional work examining the journey of pain care for youth with pain and their parents form a comprehensive research portfolio in the realm of understanding and treating chronic pain in young people. My long-term career goal is to lead a robust research program focusing on alleviating the suffering of youth and emerging adults with chronic pain.
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Robert Sinclair
Charles M. Pigott Professor in the School of Engineering
BioUsing high-resolution transmission electron microscopy, Sinclair studies microelectronic, magnetic thin film microstructure and nanomaterials.
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Kuldev Singh, MD, MPH
Professor of Ophthalmology
Current Research and Scholarly InterestsGlaucoma, clinical epidemiology
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Upinder Singh
Stanford Medicine Professor of Infectious Disease and Professor of Medicine (Infectious Diseases & Geographic Medicine), Emerita
Current Research and Scholarly InterestsOur lab elucidates the molecular basis of pathogenesis of the protozoan parasite Entamoeba histolytica. We use genetic and genomic approaches to identify novel virulence determinants and to characterize the global epidemiology of the parasite.
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Sidhartha Sinha
Assistant Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsThere are two primary and overlapping emphases of my research, both of which are driven and united by needs-based innovation and translational potential:
(1) Understanding the microenvironment of the inflamed versus normal gut in order to identify better therapeutic targets for people with immune-¬mediated GI disorders. Here, our investigations include understanding the influence and interactions of pharmacologic and dietary interventions on gut microbiome/metabolomic changes and the host immune response. In the context of providing patients with new understanding and solutions for their disease, I have led and advised on the design of both pilot and large clinical trials (including new FDA approved therapies) for anti-inflammatory therapies;
(2) Applying novel approaches and technologies (including natural language processing, computer vision, and reinforcement learning) to identify and address unmet clinical needs. In this area we have ongoing and published efforts in my lab to validate and develop solutions to pressing clinical needs. We have developed/led new drug delivery technologies with a multidisciplinary team that have shown strong potential in ongoing human IBD clinical trials. My lab has utilized both supervised and unsupervised approaches to analyze social media discourse and unstructured data sets for identifying patient needs that are rarely addressed in clinical settings. We have gained insights into patient perceptions around preventative health interventions, such as health screening and diet, including the dearth of evidence-based dietary recommendations to treat IBD (despite strong patient desire for solutions in this domain). -
Tammy Lisa Sirich
Assistant Professor of Medicine (Nephrology)
Current Research and Scholarly InterestsI conduct translational research focused on uremia and dialysis. I use mass spectrometry to conduct studies testing ways to reduce levels of solutes and examining the contribution of uremic solutes to illness.
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Stephen Skirboll
Associate Professor of Neurosurgery
Current Research and Scholarly InterestsMy research focuses on screening strategies to identify and characterize cancer stem cells (CSCs) in human gliomas. We are pursuing this in several ways: 1) a novel colony-forming antibody live cell array to identify distinct CSC surface phenotypes, 2) RNAi screens to identify kinases critical for CSC tumorigenicity, 3) high throughput small molecule and chemical screens to identify compounds that selectively kill or target CSCs, and 4) identifying CSCs using the tumor specific EGFRvIII
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Jan Skotheim
Professor of Biology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsMy overarching goal is to understand how cell growth triggers cell division. Linking growth to division is important because it allows cells to maintain specific size range to best perform their physiological functions. For example, red blood cells must be small enough to flow through small capillaries, whereas macrophages must be large enough to engulf pathogens. In addition to being important for normal cell and tissue physiology, the link between growth and division is misregulated in cancer.
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Mark Smith
Senior Research Scientist, Sarafan ChEM-H
BioDr. Mark Smith is Director of the Medicinal Chemistry within the Sarafan ChEM-H Institute Nucleus and Co-Director of the Small Molecule Portfolio in Stanford's Innovative Medicines Accelerator (IMA). In addition, Dr. Smith is Director of the Sarafan ChEM-H Undergraduate Entrepreneurship Program. Prior to Stanford, Dr. Smith was a Senior Scientist at Roche Pharmaceuticals where his research focused on the discovery of small molecule inhibitors for HIV reverse transcriptase, HCV polymerase and NS5A, influenza endonuclease and cap polymerase. Dr. Smith also led Roche's nucleoside chemistry efforts in the virology therapeutic area.
