Wu Tsai Neurosciences Institute
Showing 261-270 of 658 Results
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Yusuke Hori, MD
Instructor, Neurosurgery
BioDr. Hori received his MD from Sapporo Medical University, Japan, and during that time he served as a Medical Student Research Fellow in the Department of Pharmacology. He explored the functional role of the SIRT1 gene, a longevity-associated gene, and its association with various conditions such as muscular dystrophy. He also completed a Visiting Student Research Fellowship at the Health Sciences University of Hokkaido and participated in Human Genetics projects focusing on an association between the 27-bp deletion and 538G>A mutation in the ABCC11 Gene.
After graduating from medical school, Dr. Hori completed a neurosurgery residency at National Hospital Organization Okayama Medical Center in Japan. Subsequently, he completed a Stereotactic and Functional Neurosurgery Fellowship and then a Neurosurgical Oncology and Radiosurgery Fellowship at The Cleveland Clinic. He also completed an International Neurosurgery Fellowship at Boston Children's Hospital, Harvard Medical School. In 2022, he moved to Stanford University as a postdoctoral fellow, and under the supervision of Dr. Anca Pasca, he participated in brain organoid research focusing on hypoxic brain injuries.
Since July 2023, Dr. Hori has been working as a Clinical Instructor (Neurosurgical Oncology and Radiosurgery) in the Department of Neurosurgery at Stanford under the supervision of Dr. Steven D. Chang. His clinical interests include malignant brain and spine tumors in both adult and pediatric patients. His clinical research focuses on the application of minimally invasive treatments such as laser interstitial thermal therapy, focused ultrasound, and radiosurgery to treat various neurosurgical conditions. His current lab research aims to develop an organoid model for radiation-induced brain injuries and a high-throughput screening platform to identify novel therapeutic compounds, for which he received a Clinician Educator Grant from Stanford University Maternal and Child Health Research Institute. Outside of medicine, he enjoys playing music including guitar and drums. -
Mark Horowitz
Fortinet Founders Chair of the Department of Electrical Engineering, Yahoo! Founders Professor in the School of Engineering, Professor of Computer Science, and Senior Fellow at the Hoover Institution
BioProfessor Horowitz initially focused on designing high-performance digital systems by combining work in computer-aided design tools, circuit design, and system architecture. During this time, he built a number of early RISC microprocessors, and contributed to the design of early distributed shared memory multiprocessors. In 1990, Dr. Horowitz took leave from Stanford to help start Rambus Inc., a company designing high-bandwidth memory interface technology. After returning in 1991, his research group pioneered many innovations in high-speed link design, and many of today’s high speed link designs are designed by his former students or colleagues from Rambus.
In the 2000s he started a long collaboration with Prof. Levoy on computational photography, which included work that led to the Lytro camera, whose photographs could be refocused after they were captured.. Dr. Horowitz's current research interests are quite broad and span using EE and CS analysis methods to problems in neuro and molecular biology to creating new agile design methodologies for analog and digital VLSI circuits. He remains interested in learning new things, and building interdisciplinary teams. -
Hadi Hosseini
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsOur lab’s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).
The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders. -
Roger Howe
William E. Ayer Professor of Electrical Engineering, Emeritus
BioDesign and fabrication of sensors and actuators using micro and nanotechnologies, with applications to information processing and energy conversion.
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Anca M. Pasca, MD
Assistant Professor of Pediatrics
Current Research and Scholarly InterestsI am a physician-scientist, neonatologist, and stem cell biologist whose research focuses on understanding mechanisms of human brain development, neuroinflammation, and neurological injury using patient-derived stem cell models.
I was among the early pioneers of three-dimensional human cortical organoid technologies and contributed to development of foundational protocols for generating region-specific human brain organoids from pluripotent stem cells. My work helped establish the feasibility of modeling human brain development and disease using stem cell-derived tissues and has contributed to the widespread adoption of organoid technologies across neuroscience, regenerative medicine, and translational research.
A major focus of my laboratory is the development of increasingly sophisticated multicellular organoid and assembloid systems that incorporate diverse neuronal and glial populations to model complex human brain circuitry and disease processes. We integrate stem cell biology, organoid engineering, CRISPR-based genome editing, single-cell transcriptomics, epigenomics, high-content imaging, and computational approaches to identify disease mechanisms and therapeutic targets. These technologies have been applied to studies of hypoxic brain injury, 22q11.2 deletion syndrome, Trisomy 21 (Down Syndrome), Trisomy 18, narcolepsy, Alzheimer's and Parkinson's Disease. -
Yang Hu, MD, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsThe ultimate goal of the laboratory is to develop efficient therapeutic strategies to achieve CNS neural repair, through promoting neuroprotection, axon regeneration and functional recovery.
More specifically, we study retinal ganglion cell (RGC) and optic nerve in various optic neuropathies including traumatic, glaucomatous and inflammatory optic nerve injuries to fully understand the molecular mechanisms of CNS neurodegeneration and axon regeneration failure. -
Ting-Ting Huang
Associate Professor (Research) of Neurology (Adult Neurology), Emerita
Current Research and Scholarly InterestsWe study the role of oxygen free radicals in oxidative tissue damage and degeneration. Our research tools include transgenic and knockout mice and tissue culture cells for in vitro gene expression.
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Andrew D. Huberman
Associate Professor of Neurobiology and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsAndrew Huberman is a tenured associate professor of neurobiology and of ophthalmology at Stanford University School of Medicine, where he directs the Huberman Lab. After earning his B.A. from the University of California, Santa Barbara and completing M.A. and Ph.D. degrees in neuroscience at UC Berkeley and UC Davis, he conducted post-doctoral work at Stanford.
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John Huguenard
Professor of Neurology and Neurological Sciences (Neurology Research), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology
Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.
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Keith Humphreys
Esther Ting Memorial Professor and Professor, by courtesy, of Health Policy
Current Research and Scholarly InterestsDr. Humphreys researches individual and societal level interventions for addictive and psychiatric disorders. He focuses particularly on evaluating the outcomes of professionally-administered treatments and peer-operated self-help groups (e.g., Alcoholics Anonymous), and, analyzing the impact of public policies touching addiction, mental health, public health, and public safety.