Wu Tsai Neurosciences Institute
Showing 281-300 of 672 Results
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Peter K. Jackson
Professor of Microbiology and Immunology (Baxter Labs) and of Pathology
Current Research and Scholarly InterestsDr. Jackson’s lab studies how primary cilia organize hormone, metabolite, and growth factor signaling in metabolic tissues and how their disruption causes obesity and diabetes. A second focus is defining the KRAS driven secreted factor networks that rewire the tumor microenvironment in lung and pancreatic cancers to promote immune evasion and therapeutic resistance. This work is revealing new secreted drug targets and combination strategies for precision oncology and metabolic disease.
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Abhi Jain
Clinical Assistant Professor, Radiology
BioDr. Jain is a neuroradiologist and a Certified Imaging Informatics Professional (CIIP) whose academic work bridges day-to-day neuroradiology practice with imaging informatics and clinically grounded artificial intelligence (AI).
His clinical research interests include quantitative imaging and radiomics in cerebrovascular disease, with particular emphasis on intracerebral hemorrhage (ICH), and imaging biomarkers in the aging brain and neurodegeneration, including limbic-predominant age-related TDP-43 encephalopathy (LATE).
His AI/informatics and quality-improvement interests include large language models (LLMs) for radiology reporting support and clinical decision support, with an emphasis on real-world evaluation and workflow integration.
His education interests focus on modern, technology-enabled neuroradiology teaching, including tailored language models and extended reality (XR; augmented/virtual/mixed reality) approaches to strengthen trainee learning. -
Siddhartha Jaiswal
Associate Professor of Pathology
Current Research and Scholarly InterestsWe identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.
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Daniel Jarosz
Senior Associate Dean, Basic Science, Professor of Chemical and Systems Biology and of Developmental Biology
Current Research and Scholarly InterestsMy laboratory studies conformational switches in evolution, disease, and development. We focus on how molecular chaperones, proteins that help other biomolecules to fold, affect the phenotypic output of genetic variation. To do so we combine classical biochemistry and genetics with systems-level approaches. Ultimately we seek to understand how homeostatic mechanisms influence the acquisition of biological novelty and identify means of manipulating them for therapeutic and biosynthetic benefit.
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Booil Jo
Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsLatent Variable Modeling, Causal Inference, Longitudinal Data Analysis, Missing Data Analysis, Mixture and Growth Mixture Modeling, Prevention Science Methodology.
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Julia Kaltschmidt
Professor of Neurosurgery
Current Research and Scholarly InterestsThe lab’s primary research interest is to understand how specific neuronal circuits are established. We use mouse genetics, combinatorial immunochemical labeling and high-resolution laser scanning microscopy to identify, manipulate, and quantitatively analyze synaptic contacts within the complex neuronal milieu of the spinal cord and the enteric nervous system.
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Tahereh Kamali
Instructor, Adult Neurology
Current Research and Scholarly InterestsAI for Healthcare, Neuroimaging, Biomarkers Development
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Spyros Karadimas, MD, PhD
Assistant Professor of Neurosurgery
BioDr. Spyridon Karadimas is a board-certified, fellowship-trained cerebrovascular neurosurgeon and physician-scientist with Stanford Health Care. He is also an assistant professor in the Department of Neurosurgery at Stanford University School of Medicine.
Dr. Karadimas offers advanced, personalized treatment for complex vascular disorders of the brain, neck, and spine in both adults and children. His expertise spans brain aneurysms, arteriovenous malformations, cavernous malformations, arteriovenous fistulas, Moyamoya disease, stroke, and carotid artery disease. Dr. Karadimas is a rare combination of surgeon, scientist, and innovator dedicated to advancing patient care and shaping the future of cerebrovascular neurosurgery.
Dr. Karadimas directs a basic and translational research program focused on the neural circuits of motor control and stroke recovery. His laboratory integrates systems neuroscience, in vivo imaging, electrophysiology, and brain-computer interface development to uncover the principles of neuroplasticity, or how the brain adapts to change. This knowledge allows him to create new ways to help people move again after a brain injury.
Dr. Karadimas has published his research as first author in peer-reviewed journals such as Nature, Nature Neuroscience and Science Translational Medicine. His work has received editorial highlight at Nature Reviews Neuroscience. He has presented to his peers at international, national, and regional meetings, including those of the American Academy of Neurological Surgery, American Association of Neurological Surgeons (AANS), European Association of Neurosurgical Societies, and World Federation of Skull Base Societies.
Dr. Karadimas is a fellow of the Royal College of Surgeons of Canada and American Association of Neurological Surgeons as well as member of the Congress of Neurological Surgeons, and the North American Skull Base Society. -
Maya M. Kasowski
Assistant Professor of Pathology, of Medicine (Pulmonary, Allergy and Critical Care Medicine) and, by courtesy, of Genetics
BioI am a clinical pathologist and assistant professor in the Departments of Medicine, Pathology, and Genetics (by courtesy) at Stanford. I completed my MD-PhD training at Yale University and my residency training and a post-doctoral fellowship in the Department of Genetics at Stanford University. My experiences as a clinical pathologist and genome scientist have made me passionate about applying cutting-edge technologies to primary patient specimens in order to characterize disease pathologies at the molecular level. The core focus of my lab is to study the mechanisms by which genetic variants influence the risk of disease through effects on intermediate molecular phenotypes.
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Noa Katz
Research Professional, Chemical Engineering
BioNoa Katz is a Stanford Science Fellow and an EMBO and Fulbright postdoctoral scholar at Stanford University. She implements biomolecular gene circuits to study and manipulate the central nervous system to promote therapeutic applications for neural repair and autism.
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Makoto Kawai
Clinical Professor, Psychiatry and Behavioral Sciences - Sleep Medicine
BioI am a physician scientist in the field of sleep medicine in aging and brain function. Using combined polysomnogram and novel neuroimaging technology, I aim to identify potential sleep biomarkers to investigate the mechanism of progression from normal aging to Mild Cognitive Impairment (MCI) or dementia. I also investigate the impact of sleep on cognitive/affective function or behavior abnormality in various neurodevelopmental and neurodegenerative disorders.
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Mark A. Kay, M.D., Ph.D.
Dennis Farrey Family Professor of Pediatrics, and Professor of Genetics
Current Research and Scholarly InterestsMark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.
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Corey Keller, MD, PhD
Associate Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
Current Research and Scholarly InterestsThe goal of my lab is to understand the fundamental principles of human brain plasticity and build trans-diagnostic real-time monitoring platforms for personalized neurotherapeutics.
We use an array of neuroscience methods to better understand the basic principles of how to create change in brain circuits. We use this knowledge to develop more effective treatment strategies for depression and other psychiatric disorders. -
Kevin Kelley
Assistant Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology)
BioAs a neuroscientist and psychiatrist, I am motivated by how little we understand about the pathophysiology of psychiatric disorders and hope that further knowledge will help to alleviate the ongoing distress of many of our patients. My research program leverages computational genomics, human brain cellular models, and molecular neuroscience techniques to understand the cellular and molecular mechanisms of human brain development and how dysfunction in these processes lead to psychiatric disorders.
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Oussama Khatib
Weichai Professor and Professor, by courtesy, of Electrical Engineering
BioRobotics research on novel control architectures, algorithms, sensing, and human-friendly designs for advanced capabilities in complex environments. With a focus on enabling robots to interact cooperatively and safely with humans and the physical world, these studies bring understanding of human movements for therapy, athletic training, and performance enhancement. Our work on understanding human cognitive task representation and physical skills is enabling transfer for increased robot autonomy. With these core capabilities, we are exploring applications in healthcare and wellness, industry and service, farms and smart cities, and dangerous and unreachable settings -- deep in oceans, mines, and space.
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Chaitan Khosla
Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry
Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.
For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.
For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine. -
Butrus Khuri-Yakub
Professor (Research) of Electrical Engineering, Emeritus
BioButrus (Pierre) T. Khuri-Yakub is a Professor of Electrical Engineering at Stanford University. He received the BS degree from the American University of Beirut, the MS degree from Dartmouth College, and the Ph.D. degree from Stanford University, all in electrical engineering. His current research interests include medical ultrasound imaging and therapy, ultrasound neuro-stimulation, chemical/biological sensors, gas flow and energy flow sensing, micromachined ultrasonic transducers, and ultrasonic fluid ejectors. He has authored over 600 publications and has been principal inventor or co-inventor of 107 US and international issued patents. He was awarded the Medal of the City of Bordeaux in 1983 for his contributions to Nondestructive Evaluation, the Distinguished Advisor Award of the School of Engineering at Stanford University in 1987, the Distinguished Lecturer Award of the IEEE UFFC society in 1999, a Stanford University Outstanding Inventor Award in 2004, Distinguished Alumnus Award of the School of Engineering of the American University of Beirut in 2005, Stanford Biodesign Certificate of Appreciation for commitment to educate, mentor and inspire Biodesgin Fellows, 2011, and 2011 recipient of IEEE Rayleigh award.
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Mathew Kiang
Assistant Professor of Epidemiology and Population Health (Epidemiology)
BioI am an assistant professor in the Department of Epidemiology and Population Health. My research lies at the intersection of computational epidemiology and social epidemiology. Methodologically, my work revolves around combining disparate data sources in epidemiologically meaningful ways. For example, I work with individual-level, non-health data (e.g., GPS, accelerometer, and other sensor data from smartphones), traditional health data (e.g., survey, health systems, or death certificate data), and third-party data (e.g., cellphone providers or ad-tech data). To do this, I use a variety of methods such as joint Bayesian spatial models, traditional epidemiologic models, dynamical models, microsimulation, and demographic analysis. Substantively, my work focuses on socioeconomic and racial/ethnic inequities, substance use, and child health. For example, recently, my work has examined inequities in COVID-19 vaccine distribution, cause-specific excess mortality, and drug poisonings. Other work has examined the impact of changing vaccination rates on the reemergence of infectious diseases and the prevalence of parental death among children.
